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Reconstructing pathogen dynamics from genetic data as they become available during an outbreak or epidemic represents an important statistical scenario in which observations arrive sequentially in time and one is interested in performing…

Populations and Evolution · Quantitative Biology 2020-02-04 Mandev S. Gill , Philippe Lemey , Marc A. Suchard , Andrew Rambaut , Guy Baele

Many applications in medical statistics as well as in other fields can be described by transitions between multiple states (e.g. from health to disease) experienced by individuals over time. In this context, multi-state models are a popular…

Epidemic models are useful tools in the fight against infectious diseases, as they allow policy makers to test and compare various strategies to limit disease transmission while mitigating collateral damage on the economy. Epidemic models…

Populations and Evolution · Quantitative Biology 2021-08-18 Joseph D. Peterson , Ronojoy Adhikari

We study the problem of non-parametric Bayesian estimation of the intensity function of a Poisson point process. The observations are $n$ independent realisations of a Poisson point process on the interval $[0,T]$. We propose two related…

Methodology · Statistics 2020-03-31 Shota Gugushvili , Frank van der Meulen , Moritz Schauer , Peter Spreij

Infectious disease surveillance is of great importance for the prevention of major outbreaks. Syndromic surveillance aims at developing algorithms which can detect outbreaks as early as possible by monitoring data sources which allow to…

Machine Learning · Computer Science 2021-02-01 Moritz Kulessa , Eneldo Loza Mencía , Johannes Fürnkranz

This paper develops a class of Bayesian non- and semiparametric methods for estimating regression curves and surfaces. The main idea is to model the regression as locally linear, and then place suitable local priors on the local parameters.…

Methodology · Statistics 2026-02-26 Nils Lid Hjort

There is a growing interest in the so-called Bayesian Predictive Inference approach, which allows to perform Bayesian inference without specifying the likelihood and prior of the model, or the need of any MCMC. Instead, only a sequence of…

Statistics Theory · Mathematics 2025-09-30 Marco Battiston , Lorenzo Cappello

Our main goal in this paper is to quantitatively compare the performance of classical methods to XGBoost and convolutional neural networks in a parameter estimation problem for epidemic spread. As we use flexible two-layer random graphs as…

Social and Information Networks · Computer Science 2024-07-11 Ágnes Backhausz , Edit Bognár , Villő Csiszár , Damján Tárkányi , András Zempléni

Forecasting the occurrence and absence of novel disease outbreaks is essential for disease management. Here, we develop a general model, with no real-world training data, that accurately forecasts outbreaks and non-outbreaks. We propose a…

Machine Learning · Computer Science 2024-04-16 Shan Gao , Amit K. Chakraborty , Russell Greiner , Mark A. Lewis , Hao Wang

Based on a novel dynamic Whittle likelihood approximation for locally stationary processes, a Bayesian nonparametric approach to estimating the time-varying spectral density is proposed. This dynamic frequency-domain based likelihood…

Methodology · Statistics 2023-03-22 Yifu Tang , Claudia Kirch , Jeong Eun Lee , Renate Meyer

Multidimensional continuous-time Markov jump processes $(Z(t))$ on $\mathbb{Z}^p$ form a usual set-up for modeling $SIR$-like epidemics. However, when facing incomplete epidemic data, inference based on $(Z(t))$ is not easy to be achieved.…

Methodology · Statistics 2014-01-03 Romain Guy , Catherine Larédo , Elisabeta Vergu

This study extends the Bayesian nonparametric instrumental variable regression model to determine the structural effects of covariates on the conditional quantile of the response variable. The error distribution is nonparametrically…

Methodology · Statistics 2016-08-30 Genya Kobayashi , Kota Ogasawara

In many cases, tainted information in a computer network can spread in a way similar to an epidemics in the human world. On the other had, information processing paths are often redundant, so a single infection occurrence can be easily…

Physics and Society · Physics 2024-03-07 Franco Bagnoli , Emanuele Bellini , Emanuele Massaro

Estimation of epidemiological and population parameters from molecular sequence data has become central to the understanding of infectious disease dynamics. Various models have been proposed to infer details of the dynamics that describe…

Populations and Evolution · Quantitative Biology 2014-12-25 Alex Popinga , Tim Vaughan , Tanja Stadler , Alexei Drummond

The massive employment of computational models in network epidemiology calls for the development of improved inference methods for epidemic forecast. For simple compartment models, such as the Susceptible-Infected-Recovered model, Belief…

Physics and Society · Physics 2017-07-05 Jacopo Bindi , Alfredo Braunstein , Luca Dall'Asta

Uncertainty can be classified as either aleatoric (intrinsic randomness) or epistemic (imperfect knowledge of parameters). The majority of frameworks assessing infectious disease risk consider only epistemic uncertainty. We only ever…

We consider the efficient estimation of the semiparametric additive transformation model with current status data. A wide range of survival models and econometric models can be incorporated into this general transformation framework. We…

Statistics Theory · Mathematics 2011-05-09 Guang Cheng , Xiao Wang

Using the continuous-time susceptible-infected-susceptible (SIS) model on networks, we investigate the problem of inferring the class of the underlying network when epidemic data is only available at population-level (i.e. the number of…

Populations and Evolution · Quantitative Biology 2019-12-05 F. Di Lauro , J. -C. Croix , M. Dashti , L. Berthouze , I. Z. Kiss

When an infectious disease strikes a population, the number of newly reported cases is often the only available information that one can obtain during early stages of the outbreak. An important goal of early outbreak analysis is to obtain a…

Quantitative Methods · Quantitative Biology 2013-05-30 Bahman Davoudi , Babak Pourbohloul , Joel Miller , Rafael Meza , Lauren Ancel Meyers , David J. D. Earn

Epidemiological models for the spread of pathogens in a population are usually only able to describe a single pathogen. This makes their application unrealistic in cases where multiple pathogens with similar symptoms are spreading…

Social and Information Networks · Computer Science 2018-05-16 Nir Levy , Michael Iv , Elad Yom-Tov
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