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Breast cancer screening plays a pivotal role in early detection and subsequent effective management of the disease, impacting patient outcomes and survival rates. This study aims to assess breast cancer screening rates nationwide in the…

Sparse reduced rank regression is an essential statistical learning method. In the contemporary literature, estimation is typically formulated as a nonconvex optimization that often yields to a local optimum in numerical computation. Yet,…

Methodology · Statistics 2022-12-06 Canhong Wen , Ruipeng Dong , Xueqin Wang , Weiyu Li , Heping Zhang

As much as data science is playing a pivotal role everywhere, healthcare also finds it prominent application. Breast Cancer is the top rated type of cancer amongst women; which took away 627,000 lives alone. This high mortality rate due to…

Machine Learning · Computer Science 2019-02-26 Vivek Kumar , Brojo Kishore Mishra , Manuel Mazzara , Dang N. H. Thanh , Abhishek Verma

To improve patient survival and treatment outcomes, early diagnosis of brain tumors is an essential task. It is a difficult task to evaluate the magnetic resonance imaging (MRI) images manually. Thus, there is a need for digital methods for…

Computer Vision and Pattern Recognition · Computer Science 2021-01-05 Ginni Garg , Ritu Garg

Machine learning method is being applied in cancer research. In this work, we propose a method to classify the small patch of triple-negative breast cancer (TNBC) tumor and use the overall percentage of "good" patches as a marker to predict…

Medical Physics · Physics 2018-09-25 Guangyuan Yu , Xuefei Li , Herbert Levine

In this paper, we present a new statistical approach to automatically identify cancer regions in pathological images. The proposed method is built from statistical theory in line with evidence-based medicine. The two core technologies are…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Toshiki Kindo

Background and Objective: Breast cancer, which accounts for 23% of all cancers, is threatening the communities of developing countries because of poor awareness and treatment. Early diagnosis helps a lot in the treatment of the disease. The…

Quantitative Methods · Quantitative Biology 2020-11-24 Hamza Saad , Nagendra Nagarur

To address an important risk classification issue that arises in clinical practice, we propose a new mixture model via latent cure rate markers for survival data with a cure fraction. In the proposed model, the latent cure rate markers are…

Applications · Statistics 2009-10-12 Sungduk Kim , Yingmei Xi , Ming-Hui Chen

Machine learning is widely used in developing computer-aided diagnosis (CAD) schemes of medical images. However, CAD usually computes large number of image features from the targeted regions, which creates a challenge of how to identify a…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Morteza Heidari , Sivaramakrishnan Lakshmivarahan , Seyedehnafiseh Mirniaharikandehei , Gopichandh Danala , Sai Kiran R. Maryada , Hong Liu , Bin Zheng

Five different threshold segmentation based approaches have been reviewed and compared over here to extract the tumor from set of brain images. This research focuses on the analysis of image segmentation methods, a comparison of five…

Computer Vision and Pattern Recognition · Computer Science 2015-03-10 Muhammad Ali Qadar , Yan Zhaowen

Objectives: Pancreatic cancer is a lethal disease, hard to diagnose and usually results in poor prognosis and high mortality. Developing an artificial intelligence (AI) algorithm to accurately and universally predict the early cancer risk…

Important objectives in cancer research are the prediction of a patient's risk based on molecular measurements such as gene expression data and the identification of new prognostic biomarkers (e.g. genes). In clinical practice, this is…

Applications · Statistics 2020-04-17 Katrin Madjar , Manuela Zucknick , Katja Ickstadt , Jörg Rahnenführer

This study enhances breast cancer prediction by using large language models to infer the likelihood of confounding diseases, namely diabetes, obesity, and cardiovascular disease, from routine clinical data. These AI-generated features…

Machine Learning · Computer Science 2025-11-25 Debmita Roy

In this paper we extend the principle of proportional representation to rankings. We consider the setting where alternatives need to be ranked based on approval preferences. In this setting, proportional representation requires that…

Computer Science and Game Theory · Computer Science 2016-12-06 Piotr Skowron , Martin Lackner , Markus Brill , Dominik Peters , Edith Elkind

The choice of the most effective treatment may eventually be influenced by breast cancer survival prediction. To predict the chances of a patient surviving, a variety of techniques were employed, such as statistical, machine learning, and…

Machine Learning · Computer Science 2023-04-18 Khaoula Chtouki , Maryem Rhanoui , Mounia Mikram , Kamelia Amazian , Siham Yousfi

In this paper, a mixed-effect modeling scheme is proposed to construct a predictor for different features of cancer tumor. For this purpose, a set of features is extracted from two groups of patients with the same type of cancer but with…

Applications · Statistics 2018-04-13 Fatemeh Nasiri , Oscar Acosta-Tamayo

Current histopathological grading of prostate cancer relies primarily on glandular architecture, largely overlooking the tumor microenvironment. Here, we present PROTAS, a deep learning framework that quantifies reactive stroma (RS) in…

In this paper, we propose a computationally efficient approach -- space(Sparse PArtial Correlation Estimation)-- for selecting non-zero partial correlations under the high-dimension-low-sample-size setting. This method assumes the overall…

Methodology · Statistics 2008-12-01 Jie Peng , Pei Wang , Nengfeng Zhou , Ji Zhu

We propose a method to accurately obtain the ratio of tumor cells over an entire histological slide. We use deep fully convolutional neural network models trained to detect and classify cells on images of H&E-stained tissue sections.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-29 Eric Cosatto , Kyle Gerard , Hans-Peter Graf , Maki Ogura , Tomoharu Kiyuna , Kanako C. Hatanaka , Yoshihiro Matsuno , Yutaka Hatanaka

Predicting risks of chronic diseases has become increasingly important in clinical practice. When a prediction model is developed in a given source cohort, there is often a great interest to apply the model to other cohorts. However, due to…

Methodology · Statistics 2020-03-05 Zheng Jiayin , Zheng Yingye , Hsu Li