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PET image reconstruction is challenging due to the ill-poseness of the inverse problem and limited number of detected photons. Recently deep neural networks have been widely and successfully used in computer vision tasks and attracted…

Computer Vision and Pattern Recognition · Computer Science 2017-10-11 Kuang Gong , Jiahui Guan , Kyungsang Kim , Xuezhu Zhang , Georges El Fakhri , Jinyi Qi , Quanzheng Li

Identifying concentrations of components from an observed mixture is a fundamental problem in signal processing. It has diverse applications in fields ranging from hyperspectral imaging to denoising biomedical sensors. This paper focuses on…

Computational Engineering, Finance, and Science · Computer Science 2016-11-17 Shahin Mohammadi , Neta Zuckerman , Andrea Goldsmith , Ananth Grama

In positron emission tomography (PET), a clear theoretical model describing how system sensitivity varies as a source is moved trans-axially within the field of view (FOV) is lacking. The current understanding and practical intuition often…

Medical Physics · Physics 2026-01-26 Boheng Lin , Zizhuo Xie , Bo Zhang , Lin Wan , Ao Qiu , Qingguo Xie

Over the past years, pseudo-healthy reconstruction for unsupervised anomaly detection has gained in popularity. This approach has the great advantage of not requiring tedious pixel-wise data annotation and offers possibility to generalize…

Image and Video Processing · Electrical Eng. & Systems 2024-01-30 Ravi Hassanaly , Camille Brianceau , Maëlys Solal , Olivier Colliot , Ninon Burgos

The purpose of this study was to show how advanced concepts of compact, lossless and "Time Of Flight" (TOF) capable electronics similar to those foreseen for the LHC and ILC experiments could be fairly and easily transferred to the medical…

Instrumentation and Detectors · Physics 2009-08-03 P. -E. Vert , J. Lecoq , G. Montarou , N. Pauna , B. Joly , M. Boutemeur , H. Mathez , R. Gaglione , P. Le Dû

We propose an image-based flow decomposition developed from the two-dimensional (2D) tensor empirical wavelet transform (EWT) (Gilles 2013). The idea is to decompose the instantaneous flow data, or its visualisation, adaptively according to…

Fluid Dynamics · Physics 2020-12-24 Jie Ren , Xuerui Mao , Song Fu

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Huidong Xie , Weijie Gan , Bo Zhou , Xiongchao Chen , Qiong Liu , Xueqi Guo , Liang Guo , Hongyu An , Ulugbek S. Kamilov , Ge Wang , Chi Liu

Positron Emission Tomography (PET) scan images are one of the bio medical imaging techniques similar to that of MRI scan images but PET scan images are helpful in finding the development of tumors.The PET scan images requires expertise in…

Neural and Evolutionary Computing · Computer Science 2013-02-27 A. Meena , K. Raja

In positron emission tomography (PET), it is indispensable to perform attenuation correction in order to obtain the quantitatively accurate activity map (tracer distribution) in the body. Generally, this is carried out based on the…

Medical Physics · Physics 2025-10-16 Liyang Hu , Chong Chen

Background: In medical imaging, images are usually treated as deterministic, while their uncertainties are largely underexplored. Purpose: This work aims at using deep learning to efficiently estimate posterior distributions of imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-03-20 Xiaofeng Liu , Thibault Marin , Tiss Amal , Jonghye Woo , Georges El Fakhri , Jinsong Ouyang

Purpose: In surgical navigation, pre-operative organ models are presented to surgeons during the intervention to help them in efficiently finding their target. In the case of soft tissue, these models need to be deformed and adapted to the…

Graphics · Computer Science 2019-04-02 Micha Pfeiffer , Carina Riediger , Jürgen Weitz , Stefanie Speidel

Dynamic positron emission tomography (PET) and kinetic modeling are pivotal in advancing tracer development research in small animal studies. Accurate kinetic modeling requires precise input function estimation, traditionally achieved via…

Computed Tomography (CT) is widely used in engineering and medicine for imaging the interior of objects, patients, or animals. If the employed X-ray source is monoenergetic, image reconstruction essentially means the inversion of a ray…

Optimization and Control · Mathematics 2022-06-08 Georgios Papanikos , Benedikt Wirth

A standard dose of radioactive tracer must be delivered into the patients body to obtain high-quality Positron Emission Tomography (PET) images for diagnostic purposes, which raises the risk of radiation harm. A reduced tracer dose, on the…

Synthetic PET images are valuable for quantitative imaging workflow development, scalable virtual imaging trials, and deep learning model training, but conventional physics-based simulation approaches are computationally intensive, limited…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Suya Li , Kaushik Dutta , Debojyoti Pal , Jingqin Luo , Kooresh I. Shoghi

Cell tracking is a subject of active research gathering great interest in medicine and biology. Positron emission tomography (PET) is well suited for tracking radio-labeled cells in vivo due to its exceptional sensitivity and whole-body…

Medical Physics · Physics 2025-09-26 Nils Marquardt , Tobias Hengsbach , Marco Mauritz , Benedikt Wirth , Klaus Schäfers

The aim of this paper is to establish a nonlinear variational approach to the reconstruction of moving density images from indirect dynamic measurements. Our approach is to model the dynamics as a hyperelastic deformation of an initial…

Numerical Analysis · Mathematics 2015-12-01 Martin Burger , Jan Modersitzki , Sebastian Suhr

EEG is a non-invasive, safe, and low-risk method to record electrophysiological signals inside the brain. Especially with recent technology developments like dry electrodes, consumer-grade EEG devices, and rapid advances in machine…

Machine Learning · Computer Science 2025-06-23 Tri Duc Ly , Gia H. Ngo

PET imaging is widely employed for observing biological metabolic activities within the human body. However, numerous benign conditions can cause increased uptake of radiopharmaceuticals, confounding differentiation from malignant tumors.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-31 Ran Hong , Yuxia Huang , Lei Liu , Zhonghui Wu , Bingxuan Li , Xuemei Wang , Qiegen Liu

Multi-modal data comprising imaging (MRI, fMRI, PET, etc.) and non-imaging (clinical test, demographics, etc.) data can be collected together and used for disease prediction. Such diverse data gives complementary information about the…

Machine Learning · Computer Science 2018-12-27 Anees Kazi , S. Arvind krishna , Shayan Shekarforoush , Karsten Kortuem , Shadi Albarqouni , Nassir Navab