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Providing examples is one of the most common way for end-users to interact with program synthesizers. However, program synthesis systems assume that examples consistent with the program are chosen at random, and do not exploit the fact that…

Artificial Intelligence · Computer Science 2022-04-07 Saujas Vaduguru , Kevin Ellis , Yewen Pu

Humans excel at continually acquiring, consolidating, and retaining information from an ever-changing environment, whereas artificial neural networks (ANNs) exhibit catastrophic forgetting. There are considerable differences in the…

Neural and Evolutionary Computing · Computer Science 2023-04-17 Fahad Sarfraz , Elahe Arani , Bahram Zonooz

Catastrophic forgetting has been the leading issue in the domain of lifelong learning in artificial systems. Current artificial systems are reasonably good at learning domains they have seen before; however, as soon as they encounter…

Machine Learning · Computer Science 2024-12-02 Ram Zaveri

Insect vision supports complex behaviors including associative learning, navigation, and object detection, and has long motivated computational models for understanding biological visual processing. However, many contemporary models…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Adam D. Hines , Karin Nordström , Andrew B. Barron

Motivation: The design of enzymes is as challenging as it is consequential for making chemical synthesis in medical and industrial applications more efficient, cost-effective and environmentally friendly. While several aspects of this…

Despite recent molecular technique improvements, biological knowledge remains incomplete. Reasoning on living systems hence implies to integrate heterogeneous and partial informations. Although current investigations successfully focus on…

Quantitative Methods · Quantitative Biology 2009-09-29 Jérémie Bourdon , Damien Eveillard , Samuel Gabillard , Theo Merle

Living systems, from single cells to higher vertebrates, receive a continuous stream of non-stationary inputs that they sense, e.g., via cell surface receptors or sensory organs. Integrating these time-varying, multi-sensory, and often…

Other Quantitative Biology · Quantitative Biology 2024-04-17 Daniel Koch , Akhilesh Nandan , Gayathri Ramesan , Aneta Koseska

Synthetic data becomes crucial for large language model training, but its effectiveness is highly inconsistent. We provide an information-theoretic account of this inconsistency: synthetic data improves a model only when the…

Machine Learning · Computer Science 2026-05-19 Hanyu Li , Zhengqi Sun , Xiaotie Deng

Quantitatively predictive models of biomolecular circuits are important tools for the design of synthetic biology and molecular communication circuits. The information content of typical time-lapse single-cell data for the inference of…

Molecular Networks · Quantitative Biology 2021-01-11 Tim Prangemeier , Christian Wildner , Maleen Hanst , Heinz Koeppl

Bacteria have been a source of inspiration for the design of evolutionary algorithms. At the beginning of the 20th century synthetic biology was born, a discipline whose goal is the design of biological systems that do not exist in nature,…

Neural and Evolutionary Computing · Computer Science 2021-01-20 A. Gargantilla Becerra , M. Gutiérrez , R. Lahoz-Beltra

Complex systems are often characterized by the interplay of multiple interconnected dynamical processes operating across a range of temporal scales. This phenomenon is widespread in both biological and artificial scenarios, making it…

Statistical Mechanics · Physics 2025-09-08 Giorgio Nicoletti , Daniel M. Busiello

Experimental science is enabled by the combination of synthesis, imaging, and functional characterization. Synthesis of a new material is typically followed by a set of characterization methods aiming to provide feedback for optimization or…

Recently, we put forwarded a redox molecular hypothesis involving the natural biophysical substrate of visual perception and imagery. Here, we explicitly propose that the feedback and feedforward iterative operation processes can be…

Neurons and Cognition · Quantitative Biology 2011-03-31 I. Bokkon , V. Salari , J. Tuszynski

It is becoming widely accepted that very early in the origin of life, even before the emergence of genetic encoding, reaction networks of diverse small chemicals might have manifested key properties of life, namely self-propagation and…

Populations and Evolution · Quantitative Biology 2023-01-05 Zhen Peng , Alex Plum , Praful Gagrani , David A. Baum

Stochastic resetting, the procedure of stopping and re-initializing random processes, has recently emerged as a powerful tool for accelerating processes ranging from queuing systems to molecular simulations. However, its usefulness is…

Statistical Mechanics · Physics 2025-03-18 Tommer D. Keidar , Ofir Blumer , Barak Hirshberg , Shlomi Reuveni

This study introduces a novel theoretical framework, the Stacked Autoencoder Evolution Hypothesis, which proposes that biological evolutionary systems operate through multi-layered self-encoding and decoding processes, analogous to stacked…

Neural and Evolutionary Computing · Computer Science 2026-02-03 Hiroyuki Iizuka

Signal processing in biological systems is delicately executed by specialised networks, which are modular assemblies of network motifs. The motifs are independently functional circuits found in enormous numbers in any living cell. A very…

Molecular Networks · Quantitative Biology 2016-12-08 Tarunendu Mapder

Artificial chemistry simulations produce many intriguing emergent behaviors, but they are often difficult to steer or control. This paper proposes a method for steering the dynamics of a classic artificial chemistry model, known as AlChemy…

Formal Languages and Automata Theory · Computer Science 2025-09-05 Devansh Vimal , Cole Mathis , Westley Weimer , Stephanie Forrest

Causal inference seeks to identify cause-and-effect interactions in coupled systems. A recently proposed method by Liang detects causal relations by quantifying the direction and magnitude of information flow between time series. The…

Data Analysis, Statistics and Probability · Physics 2024-03-20 Dionissios T. Hristopulos

We study open-ended evolution by focusing on computational and information-processing dynamics underlying major evolutionary transitions. In doing so, we consider biological organisms as hierarchical dynamical systems that generate…