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Mutational signatures are powerful summaries of the mutational processes altering the DNA of cancer cells. The usual approach to mutational signature analysis consists of decomposing the matrix of mutation counts from a sample of patients…

Methodology · Statistics 2026-02-17 Alessandro Zito , Giovanni Parmigiani , Jeffrey W. Miller

We identify a new variational inference scheme for dynamical systems whose transition function is modelled by a Gaussian process. Inference in this setting has either employed computationally intensive MCMC methods, or relied on…

Machine Learning · Statistics 2019-06-14 Alessandro Davide Ialongo , Mark van der Wilk , James Hensman , Carl Edward Rasmussen

The symmetric Nonnegative Matrix Factorization (NMF), a special but important class of the general NMF, has found numerous applications in data analysis such as various clustering tasks. Unfortunately, designing fast algorithms for the…

Machine Learning · Computer Science 2023-01-26 Xiao Li , Zhihui Zhu , Qiuwei Li , Kai Liu

In this paper we propose the first non-parametric Bayesian model using Gaussian Processes to make inference on Poisson Point Processes without resorting to gridding the domain or to introducing latent thinning points. Unlike competing…

Machine Learning · Statistics 2015-06-30 Yves-Laurent Kom Samo , Stephen Roberts

Non-negative matrix factorization (NMF) is widely used for parts-based representations, yet formal inference for covariate effects is rarely available when the basis is learned under non-negativity. We introduce non-negative matrix…

Methodology · Statistics 2026-03-03 Kenichi Satoh

Poisson non-negative matrix factorization (NMF) is a widely used method to find interpretable "parts-based" decompositions of count data. While many variants of Poisson NMF exist, existing methods assume that the "parts" in the…

Machine Learning · Computer Science 2026-01-12 Eric Weine , Peter Carbonetto , Rafael A. Irizarry , Matthew Stephens

We characterize the combinatorial structure of conditionally-i.i.d. sequences of negative binomial processes with a common beta process base measure. In Bayesian nonparametric applications, such processes have served as models for latent…

Statistics Theory · Mathematics 2016-06-24 Creighton Heaukulani , Daniel M. Roy

Nonnegative Boltzmann machines (NNBMs) are recurrent probabilistic neural network models that can describe multi-modal nonnegative data. NNBMs form rectified Gaussian distributions that appear in biological neural network models, positive…

Machine Learning · Statistics 2016-03-09 Muneki Yasuda

We perform differential expression analysis of high-throughput sequencing count data under a Bayesian nonparametric framework, removing sophisticated ad-hoc pre-processing steps commonly required in existing algorithms. We propose to use…

Applications · Statistics 2017-05-04 Siamak Zamani Dadaneh , Xiaoning Qian , Mingyuan Zhou

Many popular Bayesian nonparametric priors can be characterized in terms of exchangeable species sampling sequences. However, in some applications, exchangeability may not be appropriate. We introduce a {novel and probabilistically coherent…

Statistics Theory · Mathematics 2015-03-17 Edoardo M. Airoldi , Thiago Costa , Federico Bassetti , Fabrizio Leisen , Michele Guindani

We introduce a new dynamical system for sequentially observed multivariate count data. This model is based on the gamma--Poisson construction---a natural choice for count data---and relies on a novel Bayesian nonparametric prior that ties…

Machine Learning · Statistics 2017-01-23 Aaron Schein , Mingyuan Zhou , Hanna Wallach

Non-negative matrix factorization (NMF) is a technique for finding latent representations of data. The method has been applied to corpora to construct topic models. However, NMF has likelihood assumptions which are often violated by real…

Machine Learning · Statistics 2017-11-22 Skyler Seto , Sarah Tan , Giles Hooker , Martin T. Wells

Non-negative Matrix Factorization (NMF) is one of the most popular techniques for data representation and clustering, and has been widely used in machine learning and data analysis. NMF concentrates the features of each sample into a…

Image and Video Processing · Electrical Eng. & Systems 2021-03-26 Mulin Chen , Maoguo Gong , Xuelong Li

We present a survey of some of our recent results on Bayesian nonparametric inference for a multitude of stochastic processes. The common feature is that the prior distribution in the cases considered is on suitable sets of piecewise…

Statistics Theory · Mathematics 2024-06-04 Denis Belomestny , Frank van der Meulen , Peter Spreij

We study a general factor analysis framework where the $n$-by-$p$ data matrix is assumed to follow a general exponential family distribution entry-wise. While this model framework has been proposed before, we here further relax its…

Methodology · Statistics 2025-12-02 Liang Wang , Luis Carvalho

We introduce a dynamic generative model, Bayesian allocation model (BAM), which establishes explicit connections between nonnegative tensor factorization (NTF), graphical models of discrete probability distributions and their Bayesian…

Machine Learning · Statistics 2019-03-12 Ali Taylan Cemgil , Mehmet Burak Kurutmaz , Sinan Yildirim , Melih Barsbey , Umut Simsekli

Stochastic variational inference (SVI) is emerging as the most promising candidate for scaling inference in Bayesian probabilistic models to large datasets. However, the performance of these methods has been assessed primarily in the…

Machine Learning · Statistics 2015-06-29 Amar Shah , David A. Knowles , Zoubin Ghahramani

Latent factor models are the canonical statistical tool for exploratory analyses of low-dimensional linear structure for an observation matrix with p features across n samples. We develop a structured Bayesian group factor analysis model…

Methodology · Statistics 2015-11-12 Shiwen Zhao , Chuan Gao , Sayan Mukherjee , Barbara E Engelhardt

We develop a Bayesian nonparametric approach to a general family of latent class problems in which individuals can belong simultaneously to multiple classes and where each class can be exhibited multiple times by an individual. We introduce…

Methodology · Statistics 2013-06-11 Tamara Broderick , Lester Mackey , John Paisley , Michael I. Jordan

This paper addresses the estimation of the latent dimensionality in nonnegative matrix factorization (NMF) with the \beta-divergence. The \beta-divergence is a family of cost functions that includes the squared Euclidean distance,…

Machine Learning · Statistics 2012-10-08 Vincent Y. F. Tan , Cédric Févotte