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We present a sequential Monte Carlo sampler for coalescent based Bayesian hierarchical clustering. The model is appropriate for multivariate non-\iid data and our approach offers a substantial reduction in computational cost when compared…

Applications · Statistics 2016-08-11 Ricardo Henao , Joseph E. Lucas

Clustering is part of unsupervised analysis methods that consist in grouping samples into homogeneous and separate subgroups of observations also called clusters. To interpret the clusters, statistical hypothesis testing is often used to…

Methodology · Statistics 2022-10-25 Benjamin Hivert , Denis Agniel , Rodolphe Thiébaut , Boris P Hejblum

In the design of clinical trials, it is essential to assess the design operating characteristics (e.g., power and the type I error rate). Common practice for the evaluation of operating characteristics in Bayesian clinical trials relies on…

Methodology · Statistics 2026-03-17 Luke Hagar , Shirin Golchi

Consider a population consisting of clusters of sampling units, evolving temporally, spatially, or according to other dynamics. We wish to monitor the evolution of its means, medians, or other parameters. For administrative convenience and…

Methodology · Statistics 2020-04-30 Jiahua Chen , Yukun Liu , James Zidek

Clustering is widely used in unsupervised learning to find homogeneous groups of observations within a dataset. However, clustering mixed-type data remains a challenge, as few existing approaches are suited for this task. This study…

Machine Learning · Statistics 2025-11-26 Badih Ghattas , Alvaro Sanchez San-Benito

A sensitivity analysis in an observational study assesses the robustness of significant findings to unmeasured confounding. While sensitivity analyses in matched observational studies have been well addressed when there is a single outcome…

Methodology · Statistics 2015-11-05 Colin B. Fogarty , Dylan S. Small

We investigate a generalized empirical likelihood approach in a two-group setting where the constraints on parameters have a form of U-statistics. In this situation, the summands that consist of the constraints for the empirical likelihood…

Methodology · Statistics 2015-05-04 Jihnhee Yu , Luge Yang , Albert Vexler , Alan D. Hutson

Many decision problems cannot be solved exactly and use several estimation algorithms that assign scores to the different available options. The estimation errors can have various correlations, from low (e.g. between two very different…

Machine Learning · Computer Science 2023-09-06 Theo Delemazure , François Durand , Fabien Mathieu

Some large scale inference problems are considered based on using the relative belief ratio as a measure of statistical evidence. This approach is applied to the multiple testing problem. A particular application of this is concerned with…

Statistics Theory · Mathematics 2016-09-22 Michael Evans , Jabed Tomal

The problem of testing mutually exclusive hypotheses with dependent test statistics is considered. Bayesian and frequentist approaches to multiplicity control are studied and compared to help gain understanding as to the effect of test…

Statistics Theory · Mathematics 2016-11-21 Sean Chang , James O. Berger

The problem of large scale multiple testing arises in many contexts, including testing for pairwise interaction among large numbers of neurons. With advances in technologies, it has become common to record from hundreds of neurons…

Computation · Statistics 2017-11-02 Bin Liu , Giuseppe Vinci , Adam C. Snyder , Robert E. Kass

In multivariate or spatial extremes, inference for max-stable processes observed at a large collection of locations is among the most challenging problems in computational statistics, and current approaches typically rely on less expensive…

Computation · Statistics 2015-08-20 Stefano Castruccio , Raphaël Huser , Marc Genton

There is a growing proportion of people with several disease conditions ("multimorbidity"), placing increasing demands on healthcare systems. One hypothesis is that clusters of diseases may arise from shared underlying disease processes…

Methodology · Statistics 2025-08-15 Anthony J. Webster

Multiple testing of a single hypothesis and testing multiple hypotheses are usually done in terms of p-values. In this paper we replace p-values with their natural competitor, e-values, which are closely related to betting, Bayes factors,…

Statistics Theory · Mathematics 2021-10-26 Vladimir Vovk , Ruodu Wang

In this article, a general family of bivariate distributions is used to model competing risks data with dependent factors. The general structure of competing risks data considered here includes ties. A comprehensive inferential framework…

Methodology · Statistics 2022-06-22 Aakash Agrawal , Ayon Ganguly , Debanjan Mitra

Gaussian processes (GPs) are powerful models for human-in-the-loop experiments due to their flexibility and well-calibrated uncertainty. However, GPs modeling human responses typically ignore auxiliary information, including a priori domain…

Machine Learning · Computer Science 2025-03-07 Kaiwen Wu , Craig Sanders , Benjamin Letham , Phillip Guan

Recent work on overfitting Bayesian mixtures of distributions offers a powerful framework for clustering multivariate data using a latent Gaussian model which resembles the factor analysis model. The flexibility provided by overfitting…

Methodology · Statistics 2019-08-29 Panagiotis Papastamoulis

Determining the number of clusters is a fundamental issue in data clustering. Several algorithms have been proposed, including centroid-based algorithms using the Euclidean distance and model-based algorithms using a mixture of probability…

Machine Learning · Computer Science 2024-07-30 Ryosuke Motegi , Yoichi Seki

In cancer research, clustering techniques are widely used for exploratory analyses and dimensionality reduction, playing a critical role in the identification of novel cancer subtypes, often with direct implications for patient management.…

Methods for quantifying the similarity of datasets are relevant in applications where two or more datasets, or their underlying distributions, need to be compared, ranging from two- and k-sample testing to applications in machine learning…

Methodology · Statistics 2026-04-15 Marieke Stolte , Jörg Rahnenführer , Andrea Bommert
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