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Diffusion models have shown incredible capabilities as generative models; indeed, they power the current state-of-the-art models on text-conditioned image generation such as Imagen and DALL-E 2. In this work we review, demystify, and unify…

Machine Learning · Computer Science 2022-08-26 Calvin Luo

Magnetic Resonance Imaging generally requires long exposure times, while being sensitive to patient motion, resulting in artifacts in the acquired images, which may hinder their diagnostic relevance. Despite research efforts to decrease the…

Image and Video Processing · Electrical Eng. & Systems 2025-02-04 Paolo Angella , Vito Paolo Pastore , Matteo Santacesaria

We propose a new method, Patch-CNN, for diffusion tensor (DT) estimation from only six-direction diffusion weighted images (DWI). Deep learning-based methods have been recently proposed for dMRI parameter estimation, using either voxel-wise…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Tobias Goodwin-Allcock , Ting Gong , Robert Gray , Parashkev Nachev , Hui Zhang

Diffusion models are widely used in applications ranging from image generation to inverse problems. However, training diffusion models typically requires clean ground-truth images, which are unavailable in many applications. We introduce…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Chicago Y. Park , Shirin Shoushtari , Hongyu An , Ulugbek S. Kamilov

Diffusion model has emerged as the \emph{de-facto} model for image generation, yet the heavy training overhead hinders its broader adoption in the research community. We observe that diffusion models are commonly trained to learn all…

Computer Vision and Pattern Recognition · Computer Science 2023-11-29 Jiachen Lei , Qinglong Wang , Peng Cheng , Zhongjie Ba , Zhan Qin , Zhibo Wang , Zhenguang Liu , Kui Ren

Purpose: To propose a deep learning-based reconstruction framework for ultrafast and robust diffusion tensor imaging and fiber tractography. Methods: We propose SuperDTI to learn the nonlinear relationship between diffusion-weighted images…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Hongyu Li , Zifei Liang , Chaoyi Zhang , Ruiying Liu , Jing Li , Weihong Zhang , Dong Liang , Bowen Shen , Xiaoliang Zhang , Yulin Ge , Jiangyang Zhang , Leslie Ying

Denoising diffusion models, a class of generative models, have garnered immense interest lately in various deep-learning problems. A diffusion probabilistic model defines a forward diffusion stage where the input data is gradually perturbed…

Image and Video Processing · Electrical Eng. & Systems 2023-06-06 Amirhossein Kazerouni , Ehsan Khodapanah Aghdam , Moein Heidari , Reza Azad , Mohsen Fayyaz , Ilker Hacihaliloglu , Dorit Merhof

Each voxel in a diffusion MRI (dMRI) image contains a spherical signal corresponding to the direction and strength of water diffusion in the brain. This paper advances the analysis of such spatio-spherical data by developing convolutional…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Axel Elaldi , Guido Gerig , Neel Dey

Tractography from high-dimensional diffusion magnetic resonance imaging (dMRI) data allows brain's structural connectivity analysis. Recent dMRI studies aim to compare connectivity patterns across subject groups and disease populations to…

Mild Traumatic Brain Injury (mTBI) is a significant public health problem. The most troubling symptoms after mTBI are cognitive complaints. Studies show measurable differences between patients with mTBI and healthy controls with respect to…

Image and Video Processing · Electrical Eng. & Systems 2019-11-12 Tongda Xu , Xiyan Cai , Yao Wang , Xiuyuan Wang , Sohae Chung , Els Fieremans , Joseph Rath , Steven Flanagan , Yvonne W Lui

Diffusion Magnetic Resonance Imaging (DMRI) is the only non-invasive imaging technique which is able to detect the principal directions of water diffusion as well as neurites density in the human brain. Exploiting the ability of Spherical…

Computer Vision and Pattern Recognition · Computer Science 2017-09-04 Mauro Zucchelli , Maxime Descoteaux , Gloria Menegaz

Measuring fibre dispersion in white matter with diffusion magnetic resonance imaging (MRI) is limited by an inherent degeneracy between fibre dispersion and microscopic diffusion anisotropy (i.e., the diffusion anisotropy expected for a…

The structure of grey matter has long been a key focus in neuroscience, as cell morphology varies by type and can be affected by neurological conditions. Understanding these variations is essential for studying brain function and disease.…

Biological Physics · Physics 2025-08-27 Charlie Aird-Rossiter , Hui Zhang , Daniel C. Alexander , Derek K. Jones , Marco Palombo

Advanced diffusion MRI models are being explored to study the complex microstructure of the brain with higher accuracy. However, these techniques require long acquisition times. Simultaneous multi-slice (SMS) accelerates data acquisition by…

Medical Physics · Physics 2022-01-26 L. Tugan Muftuler , Andrew S. Nencka , Kevin M. Koch

The understanding of neurodegenerative diseases undoubtedly passes through the study of human brain white matter fiber tracts. To date, diffusion magnetic resonance imaging (dMRI) is the unique technique to obtain information about the…

Machine Learning · Computer Science 2012-07-04 Romain Giot , Christophe Charrier , Maxime Descoteaux

Today the gold standard for in vivo imaging through scattering tissue is the point-scanning two-photon microscope (PSTPM). Especially in neuroscience, PSTPM is widely used for deep-tissue imaging in the brain. However, due to sequential…

Image and Video Processing · Electrical Eng. & Systems 2020-01-03 Zhun Wei , Josiah R. Boivin , Yi Xue , Xudong Chen , Peter T. C. So , Elly Nedivi , Dushan N. Wadduwage

Diffusion probabilistic models have made their way into a number of high-profile applications since their inception. In particular, there has been a wave of research into using diffusion models in the prediction and design of biomolecular…

Biomolecules · Quantitative Biology 2024-06-05 Trevor Norton , Debswapna Bhattacharya

Diffusion models (DMs) have been adopted across diverse fields with its remarkable abilities in capturing intricate data distributions. In this paper, we propose a Fast Diffusion Model (FDM) to significantly speed up DMs from a stochastic…

Computer Vision and Pattern Recognition · Computer Science 2023-10-05 Zike Wu , Pan Zhou , Kenji Kawaguchi , Hanwang Zhang

Purpose: To facilitate the implementation/validation of signal representations and models using parametric matrix-variate distributions to approximate the diffusion tensor distribution (DTD) $\mathcal{P}(\mathbf{D})$. Theory: We establish…

Computational Engineering, Finance, and Science · Computer Science 2020-05-25 A. Reymbaut