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Diffusion magnetic resonance imaging, a non-invasive tool to infer white matter fiber connections, produces a large number of streamlines containing a wealth of information on structural connectivity. The size of these tractography outputs…

Computer Vision and Pattern Recognition · Computer Science 2018-04-17 Kuldeep Kumar , Kaleem Siddiqi , Christian Desrosiers

Confocal histology provides an opportunity to establish intra-voxel fiber orientation distributions that can be used to quantitatively assess the biological relevance of diffusion weighted MRI models, e.g., constrained spherical…

Diffusion tensor imaging (DTI) is a novel modality of magnetic resonance imaging that allows noninvasive mapping of the brain's white matter. A particular map derived from DTI measurements is a map of water principal diffusion directions,…

Applications · Statistics 2008-12-18 Armin Schwartzman , Robert F. Dougherty , Jonathan E. Taylor

Tractography is typically performed for each subject using the diffusion tensor imaging (DTI) data in its native subject space rather than in some space common to the entire study cohort. Despite performing tractography on a population…

Accurate detection and segmentation of brain tumors from magnetic resonance imaging (MRI) are essential for diagnosis, treatment planning, and clinical monitoring. While convolutional architectures such as U-Net have long been the backbone…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Arman Behnam

Fiber tractography is an important tool of computational neuroscience that enables reconstructing the spatial connectivity and organization of white matter of the brain. Fiber tractography takes advantage of diffusion Magnetic Resonance…

Image and Video Processing · Electrical Eng. & Systems 2020-09-08 Tomer Weiss , Sanketh Vedula , Ortal Senouf , Oleg Michailovich , AlexBronstein

Axons in white matter have been shown to have varying geometries within a bundle using ex vivo imaging techniques, but what does this mean for diffusion MRI (dMRI) based spherical deconvolution (SD)? SD attempts to estimate the fibre…

Medical Physics · Physics 2022-03-04 Ross Callaghan , Daniel C. Alexander , Marco Palombo , Hui Zhang

Background: Diffusion tensor imaging (DTI) has been used to characterize forearm muscle architecture. Since only uniform sampling is performed for seed points rather than fiber tracts, the tracts may be unevenly distributed in the muscle…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Yang Li , Shihan Ma , Jiamin Zhao , Qing Li , Xinjun Sheng

Tractography fiber clustering using diffusion MRI (dMRI) is a crucial strategy for white matter (WM) parcellation. Current methods primarily use the geometric information of fibers (i.e., the spatial trajectories) to group similar fibers…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Jin Wang , Bocheng Guo , Yijie Li , Junyi Wang , Yuqian Chen , Jarrett Rushmore , Nikos Makris , Yogesh Rathi , Lauren J O'Donnell , Fan Zhang

Diffusion models have demonstrated significant potential in producing high-quality images in medical image translation to aid disease diagnosis, localization, and treatment. Nevertheless, current diffusion models have limited success in…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Yunxiang Li , Hua-Chieh Shao , Xiaoxue Qian , You Zhang

We performed a PubMed search to find 148 papers published between January 2010 and December 2019 related to human brain, Diffusion Tensor Imaging (DTI), and Machine Learning (ML). The studies focused on healthy cohorts (n = 15), mental…

Machine Learning · Computer Science 2020-12-22 Ashirbani Saha , Pantea Fadaiefard , Jessica E. Rabski , Alireza Sadeghian , Michael D. Cusimano

Diffusion-weighted MRI is increasingly used to study the normal and abnormal development of fetal brain in-utero. Recent studies have shown that dMRI can offer invaluable insights into the neurodevelopmental processes in the fetal stage.…

Diffusion MRI tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections. White matter parcellation classifies tractography streamlines into clusters or anatomically meaningful tracts.…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Tengfei Xue , Fan Zhang , Chaoyi Zhang , Yuqian Chen , Yang Song , Alexandra J. Golby , Nikos Makris , Yogesh Rathi , Weidong Cai , Lauren J. O'Donnell

Diffusion MRI (dMRI) is an advanced imaging technique characterizing tissue microstructure and white matter structural connectivity of the human brain. The demand for high-quality dMRI data is growing, driven by the need for better…

Image and Video Processing · Electrical Eng. & Systems 2024-08-26 Xi Zhu , Wei Zhang , Yijie Li , Lauren J. O'Donnell , Fan Zhang

Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections at macro scale. Over the last two decades, the study of brain connectivity using…

Quantitative Methods · Quantitative Biology 2021-04-26 Fan Zhang , Alessandro Daducci , Yong He , Simona Schiavi , Caio Seguin , Robert Smith , Chun-Hung Yeh , Tengda Zhao , Lauren J. O'Donnell

\hspace{2mm} Diffusion-weighted magnetic resonance imaging (dMRI) of the brain offers unique capabilities including noninvasive probing of tissue microstructure and structural connectivity. It is widely used for clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Davood Karimi , Simon K. Warfield

Diffusion magnetic resonance imaging offers unique in vivo sensitivity to tissue microstructure in brain white matter, which undergoes significant changes during development and is compromised in virtually every neurological disorder. Yet,…

Magnetic resonance diffusion tensor imaging (DTI) is a critical tool for neural disease diagnosis. However, long scan time greatly hinders the widespread clinical use of DTI. To accelerate image acquisition, a feature-enhanced joint…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Lang Zhang , Jinling He , Dong Liang , Hairong Zheng , Yanjie Zhu

Deep learning approaches for diffusion MRI have so far focused primarily on voxel-based segmentation of lesions or white-matter fiber tracts. A drawback of representing tracts as volumetric labels, rather than sets of streamlines, is that…

Image and Video Processing · Electrical Eng. & Systems 2020-09-10 Christian Ewert , David Kügler , Anastasia Yendiki , Martin Reuter

In vivo cardiac diffusion tensor imaging (cDTI) is a promising Magnetic Resonance Imaging (MRI) technique for evaluating the micro-structure of myocardial tissue in the living heart, providing insights into cardiac function and enabling the…