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In learning-phase clinical trials in drug development, adaptive designs can be efficient and highly informative when used appropriately. In this article, we extend the multiple comparison procedures with modeling techniques (MCP-Mod)…

Methodology · Statistics 2021-08-02 Shiyang Ma , Michael P. McDermott

The problem of distributed matrix-vector product is considered, where the server distributes the task of the computation among $n$ worker nodes, out of which $L$ are compromised (but non-colluding) and may return incorrect results.…

Information Theory · Computer Science 2023-05-12 Sarthak Jain , Martina Cardone , Soheil Mohajer

We examined the efficacy of AI-assisted learning in an introductory programming course at the university level by using a GPT-4 model to generate personalized hints for compiler errors within a platform for automated assessment of…

Software Engineering · Computer Science 2024-07-26 Maciej Pankiewicz , Ryan S. Baker

The test-and-set object is a fundamental synchronization primitive for shared memory systems. A test-and-set object stores a bit, initialized to 0, and supports one operation, test&set(), which sets the bit's value to 1 and returns its…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-08-23 George Giakkoupis , Maryam Helmi , Lisa Higham , Philipp Woelfel

Estimation using pooled sampling has long been an area of interest in the group testing literature. Such research has focused primarily on the assumed use of fixed sampling plans (i), although some recent papers have suggested alternative…

Statistics Theory · Mathematics 2017-03-27 Gregory Haber , Yaakov Malinovsky , Paul Albert

We study group-testing algorithms for resolving broadcast conflicts on a multiple access channel (MAC) and for identifying the dead sensors in a mobile ad hoc wireless network. In group-testing algorithms, we are asked to identify all the…

Data Structures and Algorithms · Computer Science 2009-05-13 Michael T. Goodrich , Daniel S. Hirschberg

With the rapid development of new anti-cancer agents which are cytostatic, new endpoints are needed to better measure treatment efficacy in phase II trials. For this purpose, Von Hoff (1998) proposed the growth modulation index (GMI), i.e.…

Methodology · Statistics 2021-11-01 Li Chen , Mark Burkard , Jianrong Wu , Jill M. Kolesar , Chi Wang

In nonadaptive combinatorial group testing (CGT), it is desirable to identify a small set of up to $d$ defectives from a large population of $n$ items with as few tests (i.e. large rate) and efficient identifying algorithm as possible. In…

Combinatorics · Mathematics 2020-10-08 Jinping Fan , Hung-Lin Fu , Yujie Gu , Ying Miao , Maiko Shigeno

In the pooled data problem, the goal is to identify the categories associated with a large collection of items via a sequence of pooled tests. Each pooled test reveals the number of items in the pool belonging to each category. A prominent…

Information Theory · Computer Science 2025-09-09 Nelvin Tan , Pablo Pascual Cobo , Ramji Venkataramanan

Motivated by certain applications from physics, biochemistry, economics, and computer science, in which the objects under investigation are not accessible because of various limitations, we propose a trial-and-error model to examine…

Computational Complexity · Computer Science 2013-04-19 Xiaohui Bei , Ning Chen , Shengyu Zhang

We study the problem of stabilizing an unknown partially observable linear time-invariant (LTI) system. For fully observable systems, leveraging an unstable/stable subspace decomposition approach, state-of-art sample complexity is…

Systems and Control · Electrical Eng. & Systems 2025-03-24 Ziyi Zhang , Yorie Nakahira , Guannan Qu

Consider a collection of objects, some of which may be `bad', and a test which determines whether or not a given sub-collection contains no bad objects. The non-adaptive pooling (or group testing) problem involves identifying the bad…

Combinatorics · Mathematics 2016-09-06 David J. Balding , David C. Torney

Non-proportional hazards (NPH) are often observed in clinical trials with time-to-event endpoints. A common example is a long-term clinical trial with a delayed treatment effect in immunotherapy for cancer. When designing clinical trials…

Methodology · Statistics 2025-09-18 Yujie Zhao , Yilong Zhang , Larry Leon , Keaven M. Anderson

A non-adaptive quantitative group testing (GT) scheme based on sparse codes-on-graphs in combination with low-complexity peeling decoding was introduced and analyzed by Karimi et al.. In this work, we propose a variant of this scheme based…

Information Theory · Computer Science 2024-04-18 Mgeni Makambi Mashauri , Alexandre Graell i Amat , Michael Lentmaier

Group testing is an efficient method for testing a large population to detect infected individuals. In this paper, we consider an efficient adaptive two stage group testing scheme. Using a straightforward analysis, we characterize the…

Methodology · Statistics 2020-08-26 Arjun Kodialam

We will discuss superimposed codes and non-adaptive group testing designs arising from the potentialities of compressed genotyping models in molecular biology. The given paper was motivated by the 30th anniversary of D'yachkov-Rykov…

Information Theory · Computer Science 2014-01-30 A. D'yachkov , V. Rykov , C. Deppe , V. Lebedev

Adversarial attack perturbs an image with an imperceptible noise, leading to incorrect model prediction. Recently, a few works showed inherent bias associated with such attack (robustness bias), where certain subgroups in a dataset (e.g.…

Computer Vision and Pattern Recognition · Computer Science 2022-05-06 Gaurav Kumar Nayak , Ruchit Rawal , Rohit Lal , Himanshu Patil , Anirban Chakraborty

This work is concerned with the derivation of a robust a posteriori error estimator for a discontinuous Galerkin method discretisation of linear non-stationary convection-diffusion initial/boundary value problems and with the implementation…

Numerical Analysis · Mathematics 2012-11-16 Andrea Cangiani , Emmanuil H. Georgoulis , Stephen Metcalfe

In clinical trials, there is potential to improve precision and reduce the required sample size by appropriately adjusting for baseline variables in the statistical analysis. This is called covariate adjustment. Despite recommendations by…

Methodology · Statistics 2022-06-20 Kelly Van Lancker , Joshua Betz , Michael Rosenblum

A common feature of many recent trials evaluating the effects of immunotherapy on survival is that non-proportional hazards can be anticipated at the design stage. This raises the possibility to use a statistical method tailored towards…

Applications · Statistics 2021-08-27 Dominic Magirr , José L. Jiménez
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