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Most infectious diseases spread on a dynamic network of human interactions. Recent studies of social dynamics have provided evidence that spreading patterns may depend strongly on detailed micro-dynamics of the social system. We have…

Physics and Society · Physics 2015-09-23 Arkadiusz Stopczynski , Alex Sandy Pentland , Sune Lehmann

Bacteria can adjust the structure of colonies and biofilms to enhance their survival rate under external stress. Here, we explore the link between bacterial interaction forces and colony structure. We show that the activity of extracellular…

Signal propagation over long distances is a ubiquitous feature of multicellular communities. In biofilms of the bacterium Bacillus subtilis, we recently discovered that some, but not all, cells participate in the propagation of an…

Biological Physics · Physics 2020-07-01 Xiaoling Zhai , Joseph W. Larkin , Kaito Kikuchi , Samuel E. Redford , Gürol M. Süel , Andrew Mugler

Biological organisms are simple at heart: cells, their basic units, perform a variety of behaviors by expressing proteins from DNA-encoded genes. Gene expression though depends on sets of often-convoluted regulatory interactions known as…

Molecular Networks · Quantitative Biology 2025-08-19 Kyle R. Allison

Bacteria organize in a variety of collective states, from swarming, which has been attributed to rapid surface exploration, to biofilms, which are highly dense immobile communities attributed to stress resistance. It has been suggested that…

Microscopic organisms, such as bacteria, have the ability of colonizing surfaces and developing biofilms that can determine diseases and infections. Most bacteria secrete a significant amount of extracellular polymer substances that are…

Biological Physics · Physics 2021-05-19 Francisco Javier Lobo-Cabrera , Alessandro Patti , Fernando Govantes , Alejandro Cuetos

As cells grow and divide under a given environment, they become crowded and resources are limited, as seen in bacterial biofilms and multicellular aggregates. These cells often show strong interactions through exchanging chemicals, as in…

Cell Behavior · Quantitative Biology 2017-02-08 Jumpei F Yamagishi , Nen Saito , Kunihiko Kaneko

Immotile microbes inhabit nearly every environment on Earth, from soils and sediments to food matrices -- yet how they disperse through these physically confining environments is poorly understood. Here, we show that immotile microbial…

Many bacterial species readily develop biofilms that act as a protective matrix against external challenge, e.g. from antimicrobial treatment. Therefore, biofilms are often responsible for persistent and recurring infections. Established…

Microbiomes, which are collections of interacting microbes in an environment, often substantially impact the environmental patches or living hosts that they occupy. In microbiome models, it is important to consider both the local dynamics…

Dynamical Systems · Mathematics 2025-07-18 Michael Johnson , Mason A. Porter

Systems of dynamical interactions between competing species can be used to model many complex systems, and can be mathematically described by {\em random} networks. Understanding how patterns of activity arise in such systems is important…

Adaptation and Self-Organizing Systems · Physics 2016-01-21 Nick McCullen , Thomas Wagenknecht

During colony growth, complex interactions regulate the bacterial orientation, leading to the formation of large-scale ordered structures, including topological defects and microdomains. These structures may benefit bacterial strains,…

Biological Physics · Physics 2024-04-10 Mustafa Başaran , Y. Ilker Yaman , Tevfik Can Yuce , Roman Vetter , Askin Kocabas

Non-equilibrium thermodynamics has long been an area of substantial interest to ecologists because most fundamental biological processes, such as protein synthesis and respiration, are inherently energy-consuming. Microbial communities are…

Populations and Evolution · Quantitative Biology 2022-01-19 Jacob Cook , Samraat Pawar , Robert G. Endres

Multicellular self-organization drives development in biological organisms, yet a comprehensive theory is lacking as basic properties of cells can complicate common approaches. Framing such properties by dynamic graphs led to new…

Molecular Networks · Quantitative Biology 2026-05-26 Kyle R. Allison

Cells self-organize into functional, ordered structures during tissue morphogenesis, a process that is evocative of colloidal self-assembly into engineered soft materials. Understanding how inter-cellular mechanical interactions may drive…

Biofilms inhabit a range of environments, such as dental plaques or soil micropores, often characterized by intricate, non-even surfaces. However, the impact of surface irregularities on the population dynamics of biofilms remains elusive…

Populations and Evolution · Quantitative Biology 2023-08-31 Witold Postek , Klaudia Staskiewicz , Elin Lilja , Bartlomiej Waclaw

Bacteria generally live in complicated structures called biofilms, consisting of communicating bacterial colonies and extracellular polymeric substance (EPS). Since biofilms are related to detrimental effects such as infection or antibiotic…

Quantitative Methods · Quantitative Biology 2023-11-07 Fatih Gulec , Andrew W. Eckford

Microfiltration technology is a widely used engineering strategy for fresh water production and water treatment. The major concern in many applications is the formation of a biological fouling layer leading to increased hydraulic resistance…

Biological Physics · Physics 2021-04-12 V. Luongo , M. R. Mattei , L. Frunzo , B. D'Acunto , K. Gupta , S. Chellam , N. G. Cogan

In some conditions, bacteria self-organise into biofilms, supracellular structures made of a self-produced embedding matrix, mainly composed on polysaccharides, DNA, proteins and lipids. It is known that bacteria change their colony/matrix…

Previous work has shown that species interacting in an ecosystem and actors transacting in an economic context may have notable similarities in behavior. However, the specific mechanism that may underlie similarities in nature and human…

Physics and Society · Physics 2011-10-04 Serguei Saavedra , Felix Reed-Tsochas , Brian Uzzi