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DNA-mediated computing is a novel technology that seeks to capitalize on the enormous informational capacity of DNA and has tremendous computational ability to compete with the current silicon-mediated computing, due to massive parallelism…

Emerging Technologies · Computer Science 2017-09-01 Jian-Jun Shu , Qi-Wen Wang , Kian-Yan Yong

Complementary strands in DNA double helix show temporary fluctuational openings which are essential to biological functions such as transcription and replication of the genetic information. Such large amplitude fluctuations, known as the…

Biological Physics · Physics 2013-02-12 Marco Zoli

This paper shows how partial differential problems can be solved thanks to cellular computing and an adaptation of the Least Squares Finite Elements Method. As cellular computing can be implemented on distributed parallel architectures,…

Mathematical Physics · Physics 2014-04-03 Nicolas Fressengeas , Hervé Frezza-Buet

Technologies for sequencing (reading) and synthesizing (writing) DNA have progressed on a Moore's law-like trajectory over the last three decades. This has motivated the idea of using DNA for data storage. Theoretically, DNA-based storage…

Emerging Technologies · Computer Science 2023-07-07 Ajay Manicka , Andrew Stephan , Sriram Chari , Gemma Mendonsa , Peyton Okubo , John Stolzberg-Schray , Anil Reddy , Marc Riedel

The last decade has witnessed both quantitative and qualitative progresses in Shell Model studies, which have resulted in remarkable gains in our understanding of the structure of the nucleus. Indeed, it is now possible to diagonalize…

Nuclear Theory · Physics 2008-11-26 E. Caurier , G. Martínez-Pinedo , F. Nowacki , A. Poves , A. P. Zuker

Gel electrophoresis is a powerful experimental method to probe the topology of DNA and other biopolymers. While there is a large body of experimental work which allows us to accurately separate different topoisomers of a molecule, a full…

Soft Condensed Matter · Physics 2016-02-17 Davide Michieletto , Davide Marenduzzo , Enzo Orlandini

Binary mixtures of water with lower alcohols display non-linear phase behaviour upon mixing which are attributed to potential cluster formation at molecular level. Unravelling such elusive structures requires the investigation of…

Soft Condensed Matter · Physics 2023-10-09 Riccardo Morbidini , Robert M. Edkins , Mark Devonport , Gøran Nilsen , Tilo Seydel , Katharina Edkins

In genomics, pattern matching against a sequence of nucleotides plays a pivotal role for DNA sequence alignment and comparing genomes. This helps tackling some diseases, such as cancer in humans. The complexity of searching biological…

Quantitative Methods · Quantitative Biology 2017-10-04 Fereshte Mozafari , Hossein Babashah , Somayyeh Koohi , Zahra Kavehvash

In this paper we consider dipole-mediated correlations between DNA and enzymes in the context of their water environment. Such correlations emerge from electric dipole-dipole interactions between aromatic ring structures in DNA and in…

Biological Physics · Physics 2017-02-06 P. Kurian , A. Capolupo , T. J. A. Craddock , G. Vitiello

Because of DNA appealing features as perfect material, including minuscule size, defined structural repeat and rigidity, programmable DNA-mediated processing is a promising computing paradigm, which employs DNAs as information storing and…

Biological Physics · Physics 2015-08-17 Jian-Jun Shu , Qi-Wen Wang , Kian-Yan Yong , Fangwei Shao , Kee Jin Lee

DNA computing is an unconventional approach to computing that harnesses the parallelism and information storage capabilities of DNA molecules. It has emerged as a promising field with potential applications in solving a variety of…

Emerging Technologies · Computer Science 2024-06-04 Muhammad Asad Tariq , Rafay Junaid , Muhammad Mehdy Hasnain , Danyal Farhat

The appearance and disappearance of shells and subshells are determined using a previously introduced method of structural analysis. This work extends the approach and applies it to protons, in addition to neutrons, in an attempt to provide…

Nuclear Theory · Physics 2016-04-28 I. Bentley , Y. Colon Rodrıguez , S. Cunningham , A. Aprahamian

The approach for the description of the DNA conformational transformations on the mesoscopic scales in the frame of the double helix is presented. Due to consideration of the joint motions of DNA structural elements along the conformational…

Biomolecules · Quantitative Biology 2009-09-29 S. N. Volkov

DNA nanotechnology uses predictable interactions of nucleic acids to precisely engineer complex nanostructures. Characterizing these self-assembled structures at the single-structure level is crucial for validating their design and…

Biological Physics · Physics 2025-10-21 Wangwei Dong , Zezhou Liu , Ruiyao Liu , Deborah Kuchnir Fygenson , Walter Reisner

Today there are a plethora of many-body techniques for calculating nuclear wave functions and matrix elements. I review the status of that reliable workhorse, the interacting shell model, a.k.a. configuration-interaction methods, a.k.a.…

Nuclear Theory · Physics 2018-09-27 Calvin W. Johnson

ds-RNA and standard ds-DNA show specific structural differences in their di-nucleotide steps, piled along the helical axis. Modeling the helices of short fragments by a 3D mesoscopic Hamiltonian model, I use path integral techniques to…

Soft Condensed Matter · Physics 2023-09-11 Marco Zoli

The nuclear shell model is one of the prime many-body methods to study the structure of atomic nuclei, but it is hampered by an exponential scaling on the basis size as the number of particles increases. We present a shell-model quantum…

Quantum Physics · Physics 2023-09-18 A. Pérez-Obiol , A. M. Romero , J. Menéndez , A. Rios , A. García-Sáez , B. Juliá-Díaz

Efficiently solving NP-complete problems-such as protein structure prediction, cryptographic decryption, and vulnerability detection-remains a central challenge in computer science. Traditional electronic computers, constrained by the…

Data Structures and Algorithms · Computer Science 2025-07-18 Jin Xu , XiaoLong Shi , Xin Chen , Fang Wang , Sirui Li , Pali Ye , Boliang Zhang , Di Deng , Zheng Kou , Xiaoli Qiang

Nanoparticles tethered with DNA strands are promising building blocks for bottom-up nanotechnology, and a theoretical understanding is important for future development. Here we build on approaches developed in polymer physics to provide…

Soft Condensed Matter · Physics 2014-11-03 Chia Wei Hsu , Francesco Sciortino , Francis W. Starr

Deoxyribonucleic acid (DNA) has shown great promise in enabling computational applications, most notably in the fields of DNA digital data storage and DNA computing. Information is encoded as DNA strands, which will naturally bind in…

Machine Learning · Computer Science 2021-10-22 David Buterez