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Questions of `how best to acquire data' are essential to modeling and prediction in the natural and social sciences, engineering applications, and beyond. Optimal experimental design (OED) formalizes these questions and creates…

Methodology · Statistics 2026-05-01 Xun Huan , Jayanth Jagalur , Youssef Marzouk

Bayesian optimal design is considered for experiments where the response distribution depends on the solution to a system of non-linear ordinary differential equations. The motivation is an experiment to estimate parameters in the equations…

Methodology · Statistics 2019-05-02 Antony Overstall , David Woods , Ben Parker

We characterize $D$-optimal designs in the two-dimensional Poisson regression model with synergetic interaction and provide an explicit proof. The proof is based on the idea of reparameterization of the design region in terms of contours of…

Statistics Theory · Mathematics 2021-06-17 Fritjof Freise , Ulrike Graßhoff , Frank Röttger , Rainer Schwabe

Algorithms which compute locally optimal continuous designs often rely on a finite design space or on repeatedly solving a complex non-linear program. Both methods require extensive evaluations of the Jacobian Df of the underlying model.…

Methodology · Statistics 2021-01-18 Philipp Seufert , Jan Schwientek , Michael Bortz

In the last decade, decision diagrams (DDs) have been the basis for a large array of novel approaches for modeling and solving optimization problems. Many techniques now use DDs as a key tool to achieve state-of-the-art performance within…

Optimization and Control · Mathematics 2022-01-28 Margarita P. Castro , Andre A. Cire , J. Christopher Beck

In a previous paper it was shown that a machine learning regression problem can be solved within the framework of random function theory, with the optimal kernel analytically derived from symmetry and indifference principles and coinciding…

Machine Learning · Computer Science 2025-12-19 Yuriy N. Bakhvalov

Optimal prediction approximates the average solution of a large system of ordinary differential equations by a smaller system. We present how optimal prediction can be applied to a typical problem in the field of molecular dynamics, in…

Mathematical Physics · Physics 2008-11-15 Benjamin Seibold

One of the essential issues in decision problems and preference modeling is the number of comparisons and their pattern to ask from the decision maker. We focus on the optimal patterns of pairwise comparisons and the sequence including the…

Optimization and Control · Mathematics 2025-08-26 Zsombor Szádoczki , Sándor Bozóki , László Sipos , Zsófia Galambosi

In an order-of-addition experiment, each treatment is a permutation of m components. It is often unaffordable to test all the m! treatments, and the design problem arises. We consider a model that incorporates the order of each pair of…

Statistics Theory · Mathematics 2018-05-15 Jiayu Peng , Rahul Mukerjee , Dennis K. J. Lin

We consider repeated measurement designs when a residual or carry-over effect may be present in at most one later period. Since assuming an additive model may be unrealistic for some applications and leads to biased estimation of treatment…

Statistics Theory · Mathematics 2014-11-20 R. A. Bailey , P. Druilhet

We consider the problem of adding a fixed number of new edges to an undirected graph in order to minimize the diameter of the augmented graph, and under the constraint that the number of edges added for each vertex is bounded by an integer.…

Data Structures and Algorithms · Computer Science 2023-02-14 Florian Adriaens , Aristides Gionis

In this paper, we prove a theorem on the rate of convergence for the optimal cost computed using PS methods. It is a first proved convergence rate in the literature of PS optimal control. In addition to the high-order convergence rate, two…

Optimization and Control · Mathematics 2009-04-07 Wei Kang

The purpose of this short note is to show that the Christoffel-Darboux polynomial, useful in approximation theory and data science, arises naturally when deriving the dual to the problem of semi-algebraic D-optimal experimental design in…

Optimization and Control · Mathematics 2020-12-09 Yohann de Castro , Fabrice Gamboa , Didier Henrion , Jean Lasserre

Confidence sets play a fundamental role in statistical inference. In this paper, we consider confidence intervals for high dimensional linear regression with random design. We first establish the convergence rates of the minimax expected…

Statistics Theory · Mathematics 2015-11-30 T. Tony Cai , Zijian Guo

Twinned regression methods are designed to solve the dual problem to the original regression problem, predicting differences between regression targets rather then the targets themselves. A solution to the original regression problem can be…

Machine Learning · Computer Science 2023-01-05 Sebastian J. Wetzel

For biological experiments aiming at calibrating models with unknown parameters, a good experimental design is crucial, especially for those subject to various constraints, such as financial limitations, time consumption and physical…

Applications · Statistics 2014-07-22 Xiao Lin , Gabriel Terejanu

Standard optimality criteria (e.g. A-, D-optimality criterion, etc.) have been commonly used for obtaining optimal designs. For a given statistical model, standard criteria assume the error variance is known at the design stage. However, in…

Methodology · Statistics 2017-01-27 Md. Shaddam Hossain Bagmar , Wasimul Bari , A. H. M. Mahbub Latif

Optimal designs for generalized linear models require a prior knowledge of the regression parameters. At certain values of the parameters we propose particular assumptions which allow to derive a locally optimal design for a model without…

Statistics Theory · Mathematics 2019-06-26 Osama Idais

We consider the problem of estimating a dose-response curve. Continuous treatments arise often in practice, e.g. in the form of time spent on an operation, distance traveled to a location or dosage of a drug. Letting $A$ denote a continuous…

Methodology · Statistics 2026-04-14 Matteo Bonvini , Edward H. Kennedy

This paper addresses the problem of designing recommendation systems for social networks and e-commerce platforms from a control-theoretic perspective. We treat the design of recommendation systems as a state-feedback infinite-horizon…

Systems and Control · Electrical Eng. & Systems 2026-03-12 Simone Mariano , Paolo Frasca
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