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Face detection is a computer vision application that increasingly demands lightweight models to facilitate deployment on devices with limited computational resources. Neural network pruning is a promising technique that can effectively…

Computer Vision and Pattern Recognition · Computer Science 2025-01-29 Nikolaos Kaparinos , Vasileios Mezaris

Sequence alignment data is often ordered by coordinate (id of the reference sequence plus position on the sequence where the fragment was mapped) when stored in BAM files, as this simplifies the extraction of variants between the mapped…

Genomics · Quantitative Biology 2014-06-24 German Tischler , Steven Leonard

There is increasing demand for specialized hardware for training deep neural networks, both in edge/IoT environments and in high-performance computing systems. The design space of such hardware is very large due to the wide range of…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-05-03 Yangjie Qi , Shuo Zhang , Tarek M. Taha

Linked-Reads technologies, such as 10x Genomics, combine both the high-quality and low cost of short-reads sequencing and a long-range information, through the use of barcodes able to tag reads which originate from a common long DNA…

Genomics · Quantitative Biology 2021-03-30 Pierre Morisse , Claire Lemaitre , Fabrice Legeai

In this paper, we propose StruM, a novel structured mixed-precision-based deep learning inference method, co-designed with its associated hardware accelerator (DPU), to address the escalating computational and memory demands of deep…

Hardware Architecture · Computer Science 2025-05-20 Michael Wu , Arnab Raha , Deepak A. Mathaikutty , Martin Langhammer , Engin Tunali , Daksha Sharma

In this paper, we propose a scalable approximate multiplier design, scaleTRIM, that approximates the multiplication operation using fitted linear functions, also referred to as linearization. We show that multiplication operations can be…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-14 Ebrahim Farahmand , Mohammad Javad Askarizadeh , Ali Mahani , Behnam Ghavami , Hassan Ghasemzadeh , Muhammad Abdullah Hanif , Muhammad Shafique

High-dimensional vector similarity search (HVSS) is critical for many data processing and AI applications. However, traditional HVSS methods often require extensive data access for distance calculations, leading to inefficiencies.…

Databases · Computer Science 2025-08-26 Yitong Song , Pengcheng Zhang , Chao Gao , Bin Yao , Kai Wang , Zongyuan Wu , Lin Qu

We present an efficient and expressive tool for the instrumentation of Java programs at the bytecode-level. BISM (Bytecode-Level Instrumentation for Software Monitoring) is a light-weight Java bytecode instrumentation tool that features an…

Programming Languages · Computer Science 2021-06-04 Chukri Soueidi , Marius Monnier , Ali Kassem , Yliès Falcone

Bayesian Neural Networks (BNNs) can overcome the problem of overconfidence that plagues traditional frequentist deep neural networks, and are hence considered to be a key enabler for reliable AI systems. However, conventional hardware…

Neural and Evolutionary Computing · Computer Science 2024-01-30 Prabodh Katti , Nicolas Skatchkovsky , Osvaldo Simeone , Bipin Rajendran , Bashir M. Al-Hashimi

We develop a fast, tractable technique called Net-Trim for simplifying a trained neural network. The method is a convex post-processing module, which prunes (sparsifies) a trained network layer by layer, while preserving the internal…

Machine Learning · Computer Science 2019-02-27 Alireza Aghasi , Afshin Abdi , Justin Romberg

Large Language Models (LLMs) present significant computational and memory challenges due to their extensive size, making pruning essential for their efficient deployment. Existing one-shot pruning methods often apply uniform sparsity…

Computation and Language · Computer Science 2025-10-14 Florentin Beck , William Rudman , Carsten Eickhoff

Genome sequence analysis has enabled significant advancements in medical and scientific areas such as personalized medicine, outbreak tracing, and the understanding of evolution. Unfortunately, it is currently bottlenecked by the…

Vision Transformers (ViTs) have become one of the dominant architectures in computer vision, and pre-trained ViT models are commonly adapted to new tasks via fine-tuning. Recent works proposed several parameter-efficient transfer learning…

Computer Vision and Pattern Recognition · Computer Science 2023-11-08 Imad Eddine Marouf , Enzo Tartaglione , Stéphane Lathuilière

In this paper, we present TrimTail, a simple but effective emission regularization method to improve the latency of streaming ASR models. The core idea of TrimTail is to apply length penalty (i.e., by trimming trailing frames, see Fig.…

Summary: BWA-MEM is a new alignment algorithm for aligning sequence reads or long query sequences against a large reference genome such as human. It automatically chooses between local and end-to-end alignments, supports paired-end reads…

Genomics · Quantitative Biology 2013-05-28 Heng Li

The Closest String Problem is an NP-hard problem that aims to find a string that has the minimum distance from all sequences that belong to the given set of strings. Its applications can be found in coding theory, computational biology, and…

Artificial Intelligence · Computer Science 2024-07-19 Alireza Abdi , Marko Djukanovic , Hesam Tahmasebi Boldaji , Hadis Salehi , Aleksandar Kartelj

Stochastic gradient descent-based algorithms are widely used for training deep neural networks but often suffer from slow convergence. To address the challenge, we leverage the framework of the alternating direction method of multipliers…

Machine Learning · Computer Science 2025-02-03 Ouya Wang , Shenglong Zhou , Geoffrey Ye Li

The paper introduces a new technique for compressing Binary Decision Diagrams in those cases where random access is not required. Using this technique, compression and decompression can be done in linear time in the size of the BDD and…

Artificial Intelligence · Computer Science 2008-12-18 Esben Rune Hansen , S. Srinivasa Rao , Peter Tiedemann

Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

Hardware Architecture · Computer Science 2021-11-04 Damla Senol Cali

Genome sequence alignment is the core of many biological applications. The advancement of sequencing technologies produces a tremendous amount of data, making sequence alignment a critical bottleneck in bioinformatics analysis. The existing…

Hardware Architecture · Computer Science 2023-01-26 Weihong Xu , Saransh Gupta , Niema Moshiri , Tajana Rosing