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The epidemiological behavior of Plasmodium vivax malaria occurs across spatial scales including within-host, population, and metapopulation levels. On the within-host scale, P. vivax sporozoites inoculated in a host may form latent…

Populations and Evolution · Quantitative Biology 2023-12-12 Shoshana Elgart , Mark B. Flegg , Somya Mehra , Jennifer A. Flegg

Malaria is a serious global health problem which is especially devastating to the developing world. Mosquitoes are the carriers of the parasite responsible for the disease, and hence malaria control programs focus on controlling mosquito…

Dynamical Systems · Mathematics 2016-06-17 Bhushan Kotnis , Joy Kuri

Emerging marine infectious diseases pose a substantial threat to marine ecosystems and the conservation of their biodiversity. Compartmental models of epidemic transmission in marine sessile organisms, available only recently, are based on…

Populations and Evolution · Quantitative Biology 2022-11-03 Àlex Giménez-Romero , Federico Vazquez , Cristóbal López , Manuel A. Matías

Malaria is a vector-borne disease that exacts a grave toll in the Global South. The epidemiology of Plasmodium vivax, the most geographically expansive agent of human malaria, is characterised by the accrual of a reservoir of dormant…

Populations and Evolution · Quantitative Biology 2022-08-23 Somya Mehra , Peter G. Taylor , James M. McCaw , Jennifer A. Flegg

Malaria is a parasitic disease, transmitted by mosquito vectors. Plasmodium vivax presents particular challenges for disease control, in light of an undetectable reservoir of latent parasites (hypnozoites) within the host liver.…

Populations and Evolution · Quantitative Biology 2023-06-27 Somya Mehra , James M. McCaw , Peter G. Taylor

The motility of many parasites is critical for the infection process of their host, as exemplified by the transmission cycle of the blood fluke Schistosoma mansoni. In their human infectious stage, immature, submillimetre-scale forms of the…

Biological Physics · Physics 2016-05-16 Deepak Krishnamurthy , Georgios Katsikis , Arjun Bhargava , Manu Prakash

Plasmodium vivax is one of the most geographically widespread malaria parasites in the world due to its ability to remain dormant in the human liver as hypnozoites and subsequently reactivate after the initial infection (i.e. relapse…

Plasmodium falciparum is responsible for the majority of malaria morbidity and mortality each year. Malaria transmission rates vary by location and time of year due to climate and environmental conditions. We show the impact of these…

In vivo and in vitro cells rely on the support of an underlying biocompatible substrate, such as the extracellular matrix or a culture substrate, to spread and proliferate. The mechanical and chemical properties of such structures play a…

Soft Condensed Matter · Physics 2021-11-04 Diogo E. P. Pinto , Margarida M. Telo da Gama , Nuno A. M. Araujo

Bacteria living on surfaces use different types of motility mechanisms to move on the surface in search of food or to form micro-colonies. Twitching is one such form of motility employed by bacteria such as N. gonorrhoeae, in which the…

Biological Physics · Physics 2020-04-29 Konark Bisht , Rahul Marathe

Malaria is mosquito-borne blood disease caused by parasites of the genus Plasmodium. Conventional diagnostic tool for malaria is the examination of stained blood cell of patient in microscope. The blood to be tested is placed in a slide and…

Image and Video Processing · Electrical Eng. & Systems 2018-03-30 Suman Kunwar

Malaria is one of the most common mosquito-borne diseases widespread in tropical and subtropical regions, causing thousands of deaths every year in the world. In a previous paper, we formulated an age-structured model containing three…

Populations and Evolution · Quantitative Biology 2024-05-24 Quentin Richard , Marc Choisy , Ramsès Djidjou-Demasse , Thierry Lefèvre

We study the transport of bacteria in a porous media modeled by a square channel containing one cylindrical obstacle via molecular dynamics simulations coupled to a lattice Boltzmann fluid. Our bacteria model is a rod-shaped rigid body…

Soft Condensed Matter · Physics 2020-11-30 Miru Lee , Christoph Lohrmann , Kai Szuttor , Harold Auradou , Christian Holm

We introduce a generalized version of the frog model to describe the invasion of a parasite population in a spatially structured immobile host population with host immunity on the integer line. Parasites move according to simple symmetric…

Probability · Mathematics 2025-02-17 Sascha Franck , Cornelia Pokalyuk

Recent experiments suggest that the interplay between cells and the mechanics of their substrate gives rise to a diversity of morphological and migrational behaviors. Here, we develop a Cellular Potts Model of polarizing cells on a…

Bacteria commonly inhabit porous environments such as host tissues, soil, and marine sediments, where complex geometries constrain and redirect their motion. Although bacterial motility has been studied in porous media, the roles of cell…

Soft Condensed Matter · Physics 2025-12-22 David Gao , Zeyuan Wang , Mihika Jain , Arnold J. T. M. Mathijssen , Ran Tao

We extend a model for the morphology and dynamics of a crawling eukaryotic cell to describe cells on micropatterned substrates. This model couples cell morphology, adhesion, and cytoskeletal flow in response to active stresses induced by…

Cell Behavior · Quantitative Biology 2015-06-17 Brian A. Camley , Yanxiang Zhao , Bo Li , Herbert Levine , Wouter-Jan Rappel

Migratory and tissue resident cells exhibit highly branched morphologies to perform their function and to adapt to the microenvironment. Immune cells, for example, display transient branched shapes while exploring the surrounding tissues.…

Biological Physics · Physics 2024-04-02 Jiayi Liu , Javier Boix-Campos , Jonathan E. Ron , Johan M. Kux , Nir S. Gov , Pablo J. Sáez

Motility is a fundamental survival strategy of bacteria to navigate porous environments. Swimming cells thrive in quiescent wetlands and sediments at the bottom of the marine water column, where they mediate many essential biogeochemical…

Soft Condensed Matter · Physics 2022-01-11 Amin Dehkharghani , Nicolas Waisbord , Jeffrey S. Guasto

In this work, two mathematical models for malaria under resistance are presented. More precisely, the first model shows the interaction between humans and mosquitoes inside a patch under infection of malaria when the human population is…

Populations and Evolution · Quantitative Biology 2020-02-04 Cristhian Montoya , Jhoana P. Romero-Leiton
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