English
Related papers

Related papers: Survival under high mutation rates

200 papers

In the long run, the eventual extinction of any biological population is an inevitable outcome. While extensive research has focused on the average time it takes for a population to go extinct under various circumstances, there has been…

Populations and Evolution · Quantitative Biology 2023-07-18 David Kessler , Nadav M. Shnerb

Individuals within any species exhibit differences in size, developmental state, or spatial location. These differences coupled with environmental fluctuations in demographic rates can have subtle effects on population persistence and…

Populations and Evolution · Quantitative Biology 2015-12-16 Gregory Roth , Sebastian J. Schreiber

We describe a simple model of evolution which incorporates the branching and extinction of species lines, and also includes abiotic influences. A first principles approach is taken in which the probability for speciation and extinction are…

adap-org · Physics 2008-02-03 D. A. Head , G. J. Rodgers

Some species exhibit very high levels of DNA sequence variability; there is also evidence for the existence of heritable epigenetic variants that experience state changes at a much higher rate than sequence variants. In both cases, the…

Populations and Evolution · Quantitative Biology 2016-01-13 Brian Charlesworth , Kavita Jain

Sexually reproducing populations with small number of individuals may go extinct by stochastic fluctuations in sex determination, causing all their members to become male or female in a generation. In this work we calculate the time to…

Populations and Evolution · Quantitative Biology 2012-10-24 David M. Schneider , Eduardo do Carmo , Yaneer Bar-Yam , Marcus A. M. de Aguiar

Understanding how stochastic and non-linear deterministic processes interact is a major challenge in population dynamics theory. After a short review, we introduce a stochastic individual-centered particle model to describe the evolution in…

Probability · Mathematics 2009-06-29 Regis Ferriere , Viet Chi Tran

I study a population model in which the reproduction rate lambda is inherited with mutation, favoring fast reproducers in the short term, but conflicting with a process that eliminates agglomerations of individuals. The model is a variant…

Statistical Mechanics · Physics 2021-06-02 Ronald Dickman

We study a simple model of DNA evolution in a growing population of cells. Each cell contains a nucleotide sequence which randomly mutates at cell division. Cells divide according to a branching process. Following typical parameter values…

Probability · Mathematics 2020-06-05 David Cheek , Tibor Antal

We present a stochastic model for the size of a taxon in paleobiology, in which we allow for the evolution of new taxon members, and both individual and catastrophic extinction events. The model uses ideas from the theory of birth and death…

Biological Physics · Physics 2007-05-23 Barry D. Hughes , William J. Reed

The forest of mutations associated to a multitype branching forest is obtained by merging together all vertices of its clusters and by preserving connections between them. We first show that the forest of mutations of any mulitype branching…

Probability · Mathematics 2015-10-06 Loïc Chaumont , Thi Ngoc Anh Nguyen

We study the dynamics of an age-structured population in which the life expectancy of an offspring may be mutated with respect to that of its parent. When advantageous mutation is favored, the average fitness of the population grows…

Statistical Mechanics · Physics 2009-10-31 W. Hwang , P. L. Krapivsky , S. Redner

We consider populations structured by a phenotypic trait and a space variable, in a non-homogeneous environment. In the case of sex- ual populations, we are able to derive models close to existing mod- els in theoretical biology, from a…

Analysis of PDEs · Mathematics 2011-05-11 Sepideh Mirrahimi , Gael Raoul

The question of whether a population will persist or go extinct is of key interest throughout ecology and biology. Various mathematical techniques allow us to generate knowledge regarding individual behaviour, which can be analysed to…

Populations and Evolution · Quantitative Biology 2021-04-28 Stuart T. Johnston , Matthew J. Simpson , Edmund J. Crampin

Population expansions trigger many biomedical and ecological transitions, from tumor growth to invasions of non-native species. Although population spreading often selects for more invasive phenotypes, we show that this outcome is far from…

Populations and Evolution · Quantitative Biology 2015-12-14 Kirill S. Korolev

A strong demographic Allee effect in which the expected population growth rate is negative below a certain critical population size can cause high extinction probabilities in small introduced populations. However, many species are…

Populations and Evolution · Quantitative Biology 2013-11-22 Meike J. Wittmann , Wilfried Gabriel , Dirk Metzler

In an attempt to explain the uniqueness of the coding mechanism of living cells as contrasted with multi-species structure of ecosystems we examine two models of individuals with some replicative properties. In the first model the system…

Statistical Mechanics · Physics 2009-10-31 A. Lipowski

Aging is thought to be a consequence of intrinsic breakdowns in how genetic information is processed. But mounting experimental evidence suggests that aging can be slowed. To help resolve this mystery, I derive a mortality equation which…

Populations and Evolution · Quantitative Biology 2022-09-01 Thomas Fink

Understanding how a diversity of plants in agroecosystems affects the adaptation of pathogens in a key issue in agroecology. We analyze PDE systems describing the dynamics of adaptation of two phenotypically structured populations, under…

Analysis of PDEs · Mathematics 2021-03-08 François Hamel , Florian Lavigne , Lionel Roques

We find that the hypothesis made by Jan, Stauffer and Moseley [Theory in Biosc., 119, 166 (2000)] for the evolution of sex, namely a strategy devised to escape extinction due to too many deleterious mutations, is sufficient but not…

Soft Condensed Matter · Physics 2009-11-07 Erkan Tuzel , Volkan Sevim , Ayse Erzan

Motivated by the wide range of known self-replicating systems, some far from genetics, we study a system composed by individuals having an internal dynamics with many possible states that are partially stable, with varying mutation rates.…

Biological Physics · Physics 2015-10-07 Tommaso Brotto , Guy Bunin , Jorge Kurchan