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Bayesian experimental design (BED) is a principled framework for data-efficient design of sequential experiments. However, existing BED methods are unable to adapt to dynamic constraints inherent in real-world tasks due to budget…

Machine Learning · Statistics 2026-05-27 Yujia Guo , Daolang Huang , Xinyu Zhang , Sammie Katt , Samuel Kaski , Ayush Bharti

We propose a variance-penalized formulation of Bayesian optimal experimental design for nonlinear models that augments the classical expected utility criterion with a penalty on utility variability, yielding a mean--variance objective that…

Methodology · Statistics 2026-04-07 Wanggang Shen , Xun Huan

We address a physics-informed neural network based on the concept of random projections for the numerical solution of IVPs of nonlinear ODEs in linear-implicit form and index-1 DAEs, which may also arise from the spatial discretization of…

Numerical Analysis · Mathematics 2024-11-05 Gianluca Fabiani , Evangelos Galaris , Lucia Russo , Constantinos Siettos

We present a unified, finite-element-native variational inference framework for very high-dimensional Bayesian spatial field reconstruction in physics-based problems governed by partial differential equations (PDEs) that are nonlinear in…

Computational Engineering, Finance, and Science · Computer Science 2026-05-26 Jonas Nitzler , Maximilian Bergbauer , Phaedon-Stelios Koutsourelakis , Wolfgang A. Wall

Bayesian experimental design involves the optimal allocation of resources in an experiment, with the aim of optimising cost and performance. For implicit models, where the likelihood is intractable but sampling from the model is possible,…

Machine Learning · Statistics 2019-02-26 Steven Kleinegesse , Michael Gutmann

A critical decision process in data acquisition for mineral and energy resource exploration is how to efficiently combine a variety of sensor types and to minimize total cost. We propose a probabilistic framework for multi-objective…

Geophysics · Physics 2020-10-13 Sebastian Haan , Fabio Ramos , Dietmar Müller

A classic problem is the estimation of a set of parameters from measurements collected by only a few sensors. The number of sensors is often limited by physical or economical constraints and their placement is of fundamental importance to…

Information Theory · Computer Science 2015-06-16 Juri Ranieri , Amina Chebira , Martin Vetterli

Experimental design is a classical statistics problem and its aim is to estimate an unknown $m$-dimensional vector $\beta$ from linear measurements where a Gaussian noise is introduced in each measurement. For the combinatorial experimental…

Machine Learning · Statistics 2024-12-06 Mohit Singh , Weijun Xie

In optimal experimental design, the objective is to select a limited set of experiments that maximizes information about unknown model parameters based on factor levels. This work addresses the generalized D-optimal design problem, allowing…

Data Structures and Algorithms · Computer Science 2024-11-05 Aditya Pillai , Gabriel Ponte , Marcia Fampa , Jon Lee , and Mohit Singh , Weijun Xie

This work introduces a new method to efficiently solve optimization problems constrained by partial differential equations (PDEs) with uncertain coefficients. The method leverages two sources of inexactness that trade accuracy for speed:…

Optimization and Control · Mathematics 2019-05-20 Matthew J. Zahr , Kevin T. Carlberg , Drew P. Kouri

Efficient and effective Out-of-Distribution (OOD) detection is essential for the safe deployment of AI systems. Existing feature space methods, while effective, often incur significant computational overhead due to their reliance on…

Machine Learning · Computer Science 2024-06-05 Litian Liu , Yao Qin

The experimental design problem concerns the selection of k points from a potentially large design pool of p-dimensional vectors, so as to maximize the statistical efficiency regressed on the selected k design points. Statistical efficiency…

Machine Learning · Statistics 2017-11-15 Zeyuan Allen-Zhu , Yuanzhi Li , Aarti Singh , Yining Wang

In computational PDE-based inverse problems, a finite amount of data is collected to infer unknown parameters in the PDE. In order to obtain accurate inferences, the collected data must be informative about the unknown parameters. How to…

Numerical Analysis · Mathematics 2021-05-04 Tan Bui-Thanh , Qin Li , Leonardo Zepeda-Núñez

In the development of model predictive controllers for PDE-constrained problems, the use of reduced order models is essential to enable real-time applicability. Besides local linearization approaches, Proper Orthogonal Decomposition (POD)…

Optimization and Control · Mathematics 2020-12-15 Sebastian Peitz , Stefan Klus

Gaussian process regression uses data measured at sensor locations to reconstruct a spatially dependent function with quantified uncertainty. However, if only a limited number of sensors can be deployed, it is important to determine how to…

Numerical Analysis · Mathematics 2026-01-29 Jessie Chen , Hangjie Ji , Arvind K. Saibaba

We propose new machine learning schemes for solving high dimensional nonlinear partial differential equations (PDEs). Relying on the classical backward stochastic differential equation (BSDE) representation of PDEs, our algorithms estimate…

Probability · Mathematics 2020-06-08 Côme Huré , Huyên Pham , Xavier Warin

Designing a cost-effective sensor placement plan for sewage surveillance is a crucial task because it allows cost-effective early pandemic outbreak detection as supplementation for individual testing. However, this problem is…

Computers and Society · Computer Science 2024-09-26 Sunyu Wang , Yutong Xia , Huanfa Chen , Xinyi Tong , Yulun Zhou

Given n experiment subjects with potentially heterogeneous covariates and two possible treatments, namely active treatment and control, this paper addresses the fundamental question of determining the optimal accuracy in estimating the…

Machine Learning · Statistics 2024-11-13 Jiachun Li , David Simchi-Levi , Yunxiao Zhao

Deep generative models have been demonstrated as problematic in the unsupervised out-of-distribution (OOD) detection task, where they tend to assign higher likelihoods to OOD samples. Previous studies on this issue are usually not…

Machine Learning · Computer Science 2024-01-04 Zezhen Zeng , Bin Liu

Bayesian experimental design (BED) is a framework that uses statistical models and decision making under uncertainty to optimise the cost and performance of a scientific experiment. Sequential BED, as opposed to static BED, considers the…

Machine Learning · Statistics 2020-03-23 Steven Kleinegesse , Christopher Drovandi , Michael U. Gutmann