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A quantum Matter-Photonics framework is adapted to help scrutinize chemical reaction mechanisms and used to explore a process mapped from chemical tree topological model. The chemical concept of bond knitting/breaking is reformulated via…

Chemical Physics · Physics 2014-11-03 O. Tapia

Automated identification of protein conformational states from simulation of an ensemble of structures is a hard problem because it requires teaching a computer to recognize shapes. We adapt the naive Bayes classifier from the machine…

Computational Physics · Physics 2020-12-02 David M. Rogers

We theoretically investigate the quantum correlations (in terms of concurrence of indistinguishable electrons) in a prototype molecular system (hydrogen molecule). With the assistance of the standard approximations of the linear combination…

Quantum Physics · Physics 2016-11-18 Nikos Iliopoulos , Andreas F. Terzis

The bond graph approach to modelling biochemical networks is extended to allow hierarchical construction of complex models from simpler components. This is made possible by representing the simpler components as thermodynamically open…

Molecular Networks · Quantitative Biology 2018-08-14 Peter J. Gawthrop , Joseph Cursons , Edmund J. Crampin

Recently supervised machine learning has been ascending in providing new predictive approaches for chemical, biological and materials sciences applications. In this Perspective we focus on the interplay of machine learning algorithm with…

Situationally-aware artificial agents operating with competence in natural environments face several challenges: spatial awareness, object affordance detection, dynamic changes and unpredictability. A critical challenge is the agent's…

Robotics · Computer Science 2025-07-29 Mihai Pomarlan , Stefano De Giorgis , Rachel Ringe , Maria M. Hedblom , Nikolaos Tsiogkas

Hydrogen bonding to chloride ions has been frequently discussed over the past 5 decades. Still, the possible role of such secondary intermolecular bonding interactions in hydrogen bonded networks has not been investigated in any detail.…

Chemical Physics · Physics 2020-05-22 Ildikó Pethes , Imre Bakó , László Pusztai

Evaluating the (dis)similarity of crystalline, disordered and molecular compounds is a critical step in the development of algorithms to navigate automatically the configuration space of complex materials. For instance, a structural…

Materials Science · Physics 2020-02-06 Sandip De , Albert P. Bartók , Gábor Csányi , Michele Ceriotti

Machine learning holds the promise of learning the energy functional via examples, bypassing the need to solve complicated quantum-chemical equations and realizing efficient computing of molecular electronic properties.

Chemical Physics · Physics 2018-05-25 Ruobing Wang

Molecular structure recognition is the task of translating a molecular image into its graph structure. Significant variation in drawing styles and conventions exhibited in chemical literature poses a significant challenge for automating…

Computer Vision and Pattern Recognition · Computer Science 2023-03-22 Yujie Qian , Jiang Guo , Zhengkai Tu , Zhening Li , Connor W. Coley , Regina Barzilay

Cognition is the process of knowing. As carried out by a dynamical system, it is the process by which the system absorbs information into its state. A complex network of agents cognizes knowledge about its environment, internal dynamics and…

Multiagent Systems · Computer Science 2022-07-13 Jack Hall

The thermodynamic binding networks (TBN) model is a tool for studying engineered molecular systems. The TBN model allows one to reason about their behavior through a simplified abstraction that ignores details about molecular composition,…

Emerging Technologies · Computer Science 2021-05-13 David Haley , David Doty

Statistical learning algorithms are finding more and more applications in science and technology. Atomic-scale modeling is no exception, with machine learning becoming commonplace as a tool to predict energy, forces and properties of…

Chemical Physics · Physics 2020-12-09 Félix Musil , Michele Ceriotti

One of the main applications of atomistic computer simulations is the calculation of ligand binding energies. The accuracy of these calculations depends on the force field quality and on the thoroughness of configuration sampling. Sampling…

Computational Physics · Physics 2021-01-11 Valerio Rizzi , Luigi Bonati , Narjes Ansari , Michele Parrinello

Identifying the chemical structure from a graphical representation, or image, of a molecule is a challenging pattern recognition task that would greatly benefit drug development. Yet, existing methods for chemical structure recognition do…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Martijn Oldenhof , Edward De Brouwer , Adam Arany , Yves Moreau

Generative AI models, such as score-based diffusion models, have recently advanced the field of computational materials science by enabling the generation of new materials with desired properties. In addition, these models could also be…

Materials Science · Physics 2026-01-06 Timo Reents , Arianna Cantarella , Marnik Bercx , Pietro Bonfà , Giovanni Pizzi

Entanglement constitutes a key characteristic feature of quantum matter. Its detection, however, still faces major challenges. In this letter, we formulate a framework for probing entanglement based on machine learning techniques. The…

Quantum Physics · Physics 2021-08-18 Jun Yong Khoo , Markus Heyl

The present manuscript revisits one of the earliest approaches to treating molecular systems within the Schr\"odinger formalism of quantum mechanics: the Heitler-London (HL) model. Originally proposed in 1927 and based on a linear…

Chemical Physics · Physics 2025-11-12 Washington P. da Silva , Daniel Vieira , Jonas Maziero , Edgard P. M. Amorim

A plausible definition of "reasoning" could be "algebraically manipulating previously acquired knowledge in order to answer a new question". This definition covers first-order logical inference or probabilistic inference. It also includes…

Artificial Intelligence · Computer Science 2011-02-14 Leon Bottou

Intermolecular and long-range interactions are central to phenomena as diverse as gene regulation, topological states of quantum materials, electrolyte transport in batteries, and the universal solvation properties of water. We present a…