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The growing number of dimensionality reduction methods available for data visualization has recently inspired the development of quality assessment measures, in order to evaluate the resulting low-dimensional representation independently…

Machine Learning · Computer Science 2011-10-19 Wouter Lueks , Bassam Mokbel , Michael Biehl , Barbara Hammer

With the availability of high dimensional genetic biomarkers, it is of interest to identify heterogeneous effects of these predictors on patients' survival, along with proper statistical inference. Censored quantile regression has emerged…

Methodology · Statistics 2021-07-26 Zhe Fei , Qi Zheng , Hyokyoung G. Hong , Yi Li

Dimension reduction techniques, such as Sufficient Dimension Reduction (SDR), are indispensable for analyzing high-dimensional datasets. This paper introduces a novel SDR method named Principal Square Response Forward Regression (PSRFR) for…

Methodology · Statistics 2024-09-05 Zheng Li , Yunhao Wang , Wei Gao , Hon Keung Tony Ng

This thesis responds to the challenges of using a large number, such as thousands, of features in regression and classification problems. There are two situations where such high dimensional features arise. One is when high dimensional…

Machine Learning · Statistics 2007-09-20 Longhai Li

Minimum divergence problems under integral constraints appear throughout statistics and probability, including sequential inference, bandit theory, and distributionally robust optimization. In many such settings, dual representations are…

Information Theory · Computer Science 2026-03-24 Shubhanshu Shekhar , Shubhada Agrawal

In ultrahigh dimensional setting, independence screening has been both theoretically and empirically proved a useful variable selection framework with low computation cost. In this work, we propose a two-step framework by using marginal…

Methodology · Statistics 2017-08-11 Haolei Weng , Yang Feng , Xingye Qiao

Dimensionality reduction is often used as an initial step in data exploration, either as preprocessing for classification or regression or for visualization. Most dimensionality reduction techniques to date are unsupervised; they do not…

Machine Learning · Statistics 2020-06-17 Jake S. Rhodes , Adele Cutler , Guy Wolf , Kevin R. Moon

This work is motivated by learning the individualized minimal clinically important difference, a vital concept to assess clinical importance in various biomedical studies. We formulate the scientific question into a high-dimensional…

Methodology · Statistics 2023-03-28 Huijie Feng , Jingyi Duan , Yang Ning , Jiwei Zhao

Fast and cheaper next generation sequencing technologies will generate unprecedentedly massive and highly-dimensional genomic and epigenomic variation data. In the near future, a routine part of medical record will include the sequenced…

Genomics · Quantitative Biology 2013-01-17 Momiao Xiong , Long Ma

In this paper we present several novel efficient techniques and multidimensional data structures which can improve the decision making process in many domains. We consider online range aggregation, range selection and range weighted median…

Computational Geometry · Computer Science 2010-01-12 Madalina Ecaterina Andreica , Mugurel Ionut Andreica , Nicolae Cataniciu

In recent years, mathematical models have become an indispensable tool in the planning, evaluation, and implementation of public health interventions. Models must often provide detailed information for many levels of population…

Dynamical Systems · Mathematics 2024-06-05 Alex Viguerie , Chiara Piazzola , Md Hafizul Islam , Evin Uzun Jacobson

The root-cause diagnostics of product quality defects in multistage manufacturing processes often requires a joint identification of crucial stages and process variables. To meet this requirement, this paper proposes a novel penalized…

Applications · Statistics 2020-06-11 Cheoljoon Jeong , Xiaolei Fang

Most linear dimension reduction methods proposed in the literature can be formulated using an appropriate pair of scatter matrices, see e.g. Ye and Weiss (2003), Tyler et al. (2009), Bura and Yang (2011), Liski et al. (2014) and Luo and Li…

Methodology · Statistics 2024-04-12 Klaus Nordhausen , Hannu Oja , David E. Tyler

In this paper, we study high-dimensional sparse Quadratic Discriminant Analysis (QDA) and aim to establish the optimal convergence rates for the classification error. Minimax lower bounds are established to demonstrate the necessity of…

Methodology · Statistics 2019-12-09 T. Tony Cai , Linjun Zhang

It is important to make robust inference of the conditional average treatment effect from observational data, but this becomes challenging when the confounder is multivariate or high-dimensional. In this article, we propose a double…

Methodology · Statistics 2020-09-01 Ming-Yueh Huang , Shu Yang

Modern data sets, such as those in healthcare and e-commerce, are often derived from many individuals or systems but have insufficient data from each source alone to separately estimate individual, often high-dimensional, model parameters.…

Machine Learning · Computer Science 2024-11-14 Maryann Rui , Thibaut Horel , Munther Dahleh

Random Projection (RP) technique has been widely applied in many scenarios because it can reduce high-dimensional features into low-dimensional space within short time and meet the need of real-time analysis of massive data. There is an…

Machine Learning · Computer Science 2017-06-20 Haozhe Xie , Jie Li , Qiaosheng Zhang , Yadong Wang

We present a collection of algorithms which utilize dimensional reduction to perform mesh refinement and study possibly singular solutions of time-dependent partial differential equations. The algorithms are inspired by constructions used…

Numerical Analysis · Mathematics 2007-06-21 Panagiotis Stinis

Large multidimensionality of high-throughput datasets pertaining to cell signaling and gene regulation renders it difficult to extract mechanisms underlying the complex kinetics involving various biochemical compounds (e.g., proteins,…

Quantitative Methods · Quantitative Biology 2012-01-25 Michael Dworkin , Sayak Mukherjee , Ciriyam Jayaprakash , Jayajit Das

Modern clinical trials and cohort studies gather low-cost data on all participants but may have limited resources to assess expensive exposures such as biomarkers or genomic data. When interest lies in associations involving expensive…

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