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Within the framework of population genetics we consider the evolution of an asexual haploid population under the effect of a rapidly varying natural selection (microevolution). We focus on the case in which the environment exerting…

Populations and Evolution · Quantitative Biology 2015-06-22 Stefano Bo , Andrea Mazzolini , Antonio Celani

We reconsider the deterministic haploid mutation-selection equation with two types. This is an ordinary differential equation that describes the type distribution (forward in time) in a population of infinite size. This paper establishes…

Probability · Mathematics 2020-09-25 Ellen Baake , Fernando Cordero , Sebastian Hummel

The central goal of a dynamical theory of evolution is to abstract the mean evolutionary trajectory in the trait space by considering ecological processes at the level of the individual. In this work, we develop such a theory for a new…

Populations and Evolution · Quantitative Biology 2020-03-25 Vaibhav Madhok

We study a continuous-time dynamical system that models the evolving distribution of genotypes in an infinite population where genomes may have infinitely many or even a continuum of loci, mutations accumulate along lineages without…

Populations and Evolution · Quantitative Biology 2009-02-03 Aubrey Clayton , Steven N. Evans

Genetic drift is stochastic fluctuations of alleles frequencies in a population due to sampling effects. We consider a model of drift in an equilibrium population, with high mutation rates: few functional mutations per generation. Such…

Populations and Evolution · Quantitative Biology 2017-01-12 Alexey A. Shadrin , Dmitri V. Parkhomchuk

The dynamics of adaptation is difficult to predict because it is highly stochastic even in large populations. The uncertainty emerges from number fluctuations, called genetic drift, arising in the small number of particularly fit…

Populations and Evolution · Quantitative Biology 2015-06-30 Oskar Hallatschek , Lukas Geyrhofer

Naturally evolving proteins gradually accumulate mutations while continuing to fold to thermodynamically stable native structures. This process of neutral protein evolution is an important mode of genetic change, and forms the basis for the…

Populations and Evolution · Quantitative Biology 2007-05-23 Jesse D Bloom , Alpan Raval , Claus O Wilke

For a continuous state branching process with two types of individuals which are subject to selection and density dependent competition, we characterize the joint evolution of population size, type configurations and genealogies as the…

Probability · Mathematics 2022-11-11 Airam Blancas , Stephan Gufler , Sandra Kliem , Viet Chi Tran , Anton Wakolbinger

By exploiting an analogy between population genetics and statistical mechanics, we study the evolution of a polygenic trait under stabilizing selection, mutation, and genetic drift. This requires us to track only four macroscopic variables,…

Populations and Evolution · Quantitative Biology 2010-11-18 Harold P. de Vladar , Nick Barton

In this paper, under an abstract setting we establish the spreading properties and the existence, non-existence and global attractivity of spatially heterogeneous steady states for a large class of monotone evolution systems without the…

Dynamical Systems · Mathematics 2025-10-22 Taishan Yi , Xiao-Qiang Zhao

We seek models for the genotype evolution of agricultural animals, animals involved in primary production processes. Classical models for genotype evolution have tended to be very simple in order that analytic methods may be employed in…

Quantitative Methods · Quantitative Biology 2017-12-15 Vladimir Obolonkin , Anatoly Zherelo , George Krylov , Murray Jorgensen , Richard Spelman

We study a universal object for the genealogy of a sample in populations with mutations: the critical birth-death process with Poissonian mutations, conditioned on its population size at a fixed time horizon. We show how this process arises…

Probability · Mathematics 2014-07-30 G. Achaz , C. Delaporte , A. Lambert

The basic mechanics of evolution have been understood since Darwin. But debate continues over whether macroevolutionary phenomena are driven primary by the fitness structure of genotype space or by ecological interaction. In this paper we…

Populations and Evolution · Quantitative Biology 2012-10-22 David V. Foster , Mary M. Rorick , Tanja Gesell , Laura Feeney , Jacob G. Foster

By introducing the notions of living and dead nodes a new model of random tree evolution with continuous time parameter has been constructed. It is assumed that two random variables, the lifetime and the offspring number of living nodes…

Statistical Mechanics · Physics 2007-05-23 L. Pal

Large sets of genotypes give rise to the same phenotype because phenotypic expression is highly redundant. Accordingly, a population can accept mutations without altering its phenotype, as long as thegenotype mutates into another one on the…

Populations and Evolution · Quantitative Biology 2015-02-18 Susanna Manrubia , José A. Cuesta

The strong Allee effect plays an important role on the evolution of population in ecological systems. One important concept is the Allee threshold that determines the persistence or extinction of the population in a long time. In general, a…

Analysis of PDEs · Mathematics 2024-08-05 Fanze Kong , Juncheng Wei

We review and extend results for mutation, selection, genetic drift, and migration in a one-dimensional continuous population. The population is described by a continuous limit of the stepping stone model, which leads to the stochastic…

Populations and Evolution · Quantitative Biology 2011-04-14 K. S. Korolev , Mikkel Avlund , Oskar Hallatschek , David R. Nelson

Evolutionary dynamics is often viewed as a subtle process of change accumulation that causes a divergence among organisms and their genomes. However, this interpretation is an inheritance of a gradualistic view that has been challenged at…

Populations and Evolution · Quantitative Biology 2018-07-27 Jacobo Aguirre , Pablo Catalán , José A. Cuesta , Susanna Manrubia

Both evolution and ecology have long been concerned with the impact of variable environmental conditions on observed levels of genetic diversity within and between species. We model the evolution of a quantitative trait under selection that…

Populations and Evolution · Quantitative Biology 2014-11-17 Hannes Svardal , Claus Rueffler , Joachim Hermisson

A probability model is presented for the dynamics of mutation-selection balance in a haploid infinite-population infinite-sites setting sufficiently general to cover mutation-driven changes in full age-specific demographic schedules. The…

Populations and Evolution · Quantitative Biology 2007-05-23 David Steinsaltz , Steven N. Evans , Kenneth W. Wachter