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We successfully combine Expectation-Maximization algorithm and variational approaches for parameter learning and computing inference on Markov random felds. This is a general method that can be applied to many computer vision tasks. In this…

Computer Vision and Pattern Recognition · Computer Science 2018-05-16 Francisco Cruz , Oriol Ramos Terrades

Technology aided platforms provide reliable tools in almost every field these days. These tools being supported by computational power are significant for applications that need sensitive and precise data analysis. One such important…

Computer Vision and Pattern Recognition · Computer Science 2020-03-16 Muhammad Ali Farooq , Muhammad Aatif Mobeen Azhar , Rana Hammad Raza

In this research, we have two serum SELDI (surface-enhanced laser desorption and ionization) mass spectra (MS) datasets to be used to select features amongst them to identify proteomic cancerous serums from normal serums. Features selection…

Machine Learning · Computer Science 2021-05-06 Ahmed Farag Seddik , Hassan Mostafa Ahmed

In this study, the combination of a developing data mining technique called statistical decision tree analysis method and Raman spectroscopy was proposed to differentiate human normal leukocytes from malignant tumor cells. Statistical…

Optics · Physics 2020-12-01 Yixin Dai , Wenxue Li , Liu Wang , Chuan Luo , Qing Huang , Lin Pang

It is increasingly common clinically for cancer specimens to be examined using techniques that identify somatic mutations. In principle these mutational profiles can be used to diagnose the tissue of origin, a critical task for the 3-5% of…

Methodology · Statistics 2020-07-14 Saptarshi Chakraborty , Colin B. Begg , Ronglai Shen

MALDI mass spectrometry imaging (MALDI MSI) is a spatially resolved analytical tool for biological tissue analysis by measuring mass-to-charge ratios of ionized molecules. With increasing spatial and mass resolution of MALDI MSI data,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-04 Florian Lieb , Tobias Boskamp , Hans-Georg Stark

The application of machine learning (ML) algorithms in the intelligent diagnosis of three-phase engines has the potential to significantly enhance diagnostic performance and accuracy. Traditional methods largely rely on signature analysis,…

Signal Processing · Electrical Eng. & Systems 2024-11-14 Stepan Svirin , Artem Ryzhikov , Saraa Ali , Denis Derkach

Machine learning models for medical image analysis often suffer from poor performance on important subsets of a population that are not identified during training or testing. For example, overall performance of a cancer detection model may…

Machine Learning · Computer Science 2019-11-18 Luke Oakden-Rayner , Jared Dunnmon , Gustavo Carneiro , Christopher Ré

Automatic diagnosis of malignant melanoma highly depends on the segmentation methods used for the suspicious lesion. We suggest the parameter selection method (PSM) and maximum area method (MAM) for the segmentation of the lesion to be…

Image and Video Processing · Electrical Eng. & Systems 2020-05-05 Seungmin Park , Hyunju Lee , Kiwoon Kwon

Detecting cancers at early stages can dramatically reduce mortality rates. Therefore, practical cancer screening at the population level is needed. Here, we develop a comprehensive detection system to classify all common cancer types. By…

Molecular Networks · Quantitative Biology 2021-03-30 Anyou Wang , Rong Hai , Paul J Rider , Qianchuan He

Machine learning can precisely identify different cancer tumors at any stage by classifying cancerous and healthy samples based on their genomic profile. We have developed novel methods of MLAC (Machine Learning Against Cancer) achieving…

Genomics · Quantitative Biology 2020-09-15 Arash Hooshmand

This paper explores interpretability techniques for two of the most successful learning algorithms in medical decision-making literature: deep neural networks and random forests. We applied these algorithms in a real-world medical dataset…

Machine Learning · Computer Science 2020-02-24 Catarina Moreira , Renuka Sindhgatta , Chun Ouyang , Peter Bruza , Andreas Wichert

To improve patient survival and treatment outcomes, early diagnosis of brain tumors is an essential task. It is a difficult task to evaluate the magnetic resonance imaging (MRI) images manually. Thus, there is a need for digital methods for…

Computer Vision and Pattern Recognition · Computer Science 2021-01-05 Ginni Garg , Ritu Garg

Motivation: Biomarker discovery from high-dimensional data is a crucial problem with enormous applications in biology and medicine. It is also extremely challenging from a statistical viewpoint, but surprisingly few studies have…

Quantitative Methods · Quantitative Biology 2012-09-17 Anne-Claire Haury , Pierre Gestraud , Jean-Philippe Vert

One of the deadliest cancers, lung cancer necessitates an early and precise diagnosis. Because patients have a better chance of recovering, early identification of lung cancer is crucial. This review looks at how to diagnose lung cancer…

Machine Learning · Computer Science 2025-01-22 Omid Shahriyar , Babak Nuri Moghaddam , Davoud Yousefi , Abbas Mirzaei , Farnaz Hoseini

An early detection of different tumor subtypes is crucial for an effective guidance to personalized therapy. While much efforts focus on decoding the sequence of DNA basis to detect the genetic mutations related to cancer, it is becoming…

Molecular data from tumor profiles is high dimensional. Tumor profiles can be characterized by tens of thousands of gene expression features. Due to the size of the gene expression feature set machine learning methods are exposed to noisy…

Machine Learning · Computer Science 2020-07-14 Martin Palazzo , Pierre Beauseroy , Patricio Yankilevich

Multi-state models of cancer natural history are widely used for designing and evaluating cancer early detection strategies. Calibrating such models against longitudinal data from screened cohorts is challenging, especially when fitting…

Computation · Statistics 2025-08-14 Raphael Morsomme , Shannon Holloway , Marc Ryser , Jason Xu

Deep learning classifiers for characterization of whole slide tissue morphology require large volumes of annotated data to learn variations across different tissue and cancer types. As is well known, manual generation of digital pathology…

Image and Video Processing · Electrical Eng. & Systems 2019-07-10 Shahira Abousamra , Le Hou , Rajarsi Gupta , Chao Chen , Dimitris Samaras , Tahsin Kurc , Rebecca Batiste , Tianhao Zhao , Shroyer Kenneth , Joel Saltz

Segmentation of regions of interest (ROIs) for identifying abnormalities is a leading problem in medical imaging. Using machine learning for this problem generally requires manually annotated ground-truth segmentations, demanding extensive…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Jay J. Yoo , Khashayar Namdar , Matthias W. Wagner , Liana Nobre , Uri Tabori , Cynthia Hawkins , Birgit B. Ertl-Wagner , Farzad Khalvati