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Measurements with an atomic force microscope (AFM) offer a direct way to probe elastic properties of lipid bilayer membranes locally: provided the underlying stress-strain relation is known, material parameters such as surface tension or…

Soft Condensed Matter · Physics 2007-05-23 Davood Norouzi , Martin Michael Mueller , Markus Deserno

Despite being the main tool to visualize molecules at the atomic scale, AFM with CO-functionalized metal tips is unable to chemically identify the observed molecules. Here we present a strategy to address this challenging task using deep…

Materials Science · Physics 2025-09-03 Jaime Carracedo-Cosme , Carlos Romero-Muñiz , Pablo Pou , Rubén Pérez

The widespread application of surface-attached nanobubbles and nanodroplets in biomedical engineering and nanotechnology is limited by numerous experimental challenges, in particular, the possibility of contamination in nucleation…

Soft Condensed Matter · Physics 2016-08-30 Hongjie An , Beng Hau Tan , Claus-Dieter Ohl

Atomic force microscopy (AFM) enables high-resolution imaging and quantitative force measurement, which is critical for understanding nanoscale mechanical, chemical, and biological interactions. In dynamic AFM modes, however, interaction…

Instrumentation and Detectors · Physics 2025-06-10 Simon Laflamme , Bugrahan Guner , Omur E. Dagdeviren

Interferometry is a prime technique for modern precision measurements. Atoms, unlike light, have significant interactions with electric, magnetic, and gravitational fields, making their use in interferometric applications particularly…

Quantum Gases · Physics 2023-07-12 Maren E. Mossman , Ryan A. Corbin , Michael McNeil Forbes , Peter Engels

The reconfiguration of soft, deformable particles upon adsorption at the interface between two fluids underpins many aspects of their dynamics and interactions, ultimately controlling the macroscopic properties of particle monolayers of…

Soft Condensed Matter · Physics 2022-04-21 Jacopo Vialetto , Shivaprakash N. Ramakrishna , Lucio Isa

The mechanical properties of collagen fibrils depend on the amount and the distribution of water molecules within the fibrils. Here, we use atomic force microscopy (AFM) to study the effect of hydration on the viscoelastic properties of…

Soft Condensed Matter · Physics 2019-10-03 Manuel R. Uhlig , Robert Magerle

Atomically-resolved imaging and force measurements using the atomic force microscope (AFM) are performed most commonly in a frequency-modulation (FM) mode. This has led to spectacular results, including direct observation of the atomic…

Mesoscale and Nanoscale Physics · Physics 2018-12-26 John E. Sader , Barry D. Hughes , Ferdinand Huber , Franz J. Giessibl

Far-UV photons (E<13.6 eV) from hot massive stars regulate, or at least influence, the heating, ionization, and chemistry of most of the neutral interstellar medium. Investigating the interaction between FUV radiation and interstellar…

Astrophysics of Galaxies · Physics 2018-09-12 Javier R. Goicoechea , S. Cuadrado , J. Pety , A. Aguado , J. H. Black , E. Bron , J. Cernicharo , E. Chapillon , A. Fuente , M. Gerin , C. Joblin

The static friction between crystalline surfaces separated by a molecularly thin layer of adsorbed molecules is calculated using molecular dynamics simulations. These molecules naturally lead to a finite static friction that is consistent…

Materials Science · Physics 2009-11-07 Gang He , Mark O. Robbins

Atomic Force Microscopy - Infrared (AFM-IR) spectroscopy allows spectroscopic studies in the mid-infrared spectral region with a spatial resolution better than 50 nm. We show that the high spatial resolution can be used to perform…

Quantitative Methods · Quantitative Biology 2017-04-06 Luca Quaroni , Katarzyna Pogoda , Joanna-Wiltowska Zuber , Wojciech Kwiatek

Atomic force microscopy (AFM) is one of the most promising methods for investigating the structure of materials at the micro and nanoscale levels, as well as their local physical-mechanical properties. The experimental data obtained with…

Materials Science · Physics 2018-05-07 Oleg K. Garishin , Roman I. Izyumov , Alexander L. Svistkov

We study long-range morphological changes in atomic monolayers on solid substrates induced by different types of defects; e.g., by monoatomic steps in the surface, or by the tip of an atomic force microscope (AFM), placed at some distance…

Soft Condensed Matter · Physics 2009-11-07 H. Schiessel , G. Oshanin , A. M. Cazabat , M. Moreau

Atomic Force Microscopy - Infrared (AFM-IR) has emerged as a useful technique for measuring absorption spectra with spatial resolution better than the optical diffraction limit. The technique relies on the movement of a probe for atomic…

Applied Physics · Physics 2024-01-17 Luca Quaroni

Conformational changes drive protein function, including catalysis, allostery, and signaling. X-ray diffuse scattering from protein crystals has frequently been cited as a probe of these correlated motions, with significant potential to…

Biological Physics · Physics 2018-03-28 Ariana Peck , Frédéric Poitevin , Thomas J. Lane

Intermodulation atomic force microscopy (ImAFM) is a mode of dynamic atomic force microscopy that probes the nonlinear tip-surface force by measurement of the mixing of multiple tones in a frequency comb. A high $Q$ cantilever resonance and…

Mesoscale and Nanoscale Physics · Physics 2013-02-06 Daniel Platz , Daniel Forchheimer , Erik A. Tholén , David B. Haviland

The atomic number contrast imaging technique reveals an increase in intensity at interfaces of a high and low-density material in case of relatively thick samples. Elastic scattering factors and absorption coefficients are incorporated in a…

Computational Physics · Physics 2019-12-25 Aniruddha Dutta , Helge Heinrich

Photoinduced force microscopy (PiFM) enables nanoscale visualization of optical responses by directly detecting photoinduced forces without relying on luminescence. In molecular assemblies, intermolecular polarization coupling can generate…

Optics · Physics 2026-05-21 Masayoshi Fujii , Mamoru Tamura , Hidemasa Yamane , Hajime Ishihara

Magnetic force microscopy (MFM) allows one to image the domain structure of ferromagnetic samples by probing the dipole forces between a magnetic probe tip and a magnetic sample. The magnetic domain structure of the sample depends on the…

Instrumentation and Detectors · Physics 2014-02-24 M. Schneiderbauer , F. J. Giessibl

We show that dressing polar molecules with a far-off-resonant optical field leads to new types of intermolecular potentials, which undergo a crossover from the inverse-power to oscillating behavior depending on the intermolecular distance,…

Atomic Physics · Physics 2011-06-01 Mikhail Lemeshko