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Imaging algorithms form powerful analysis tools for VLBI data analysis. However, these tools cannot measure certain image features (e.g., ring diameter) by their non-parametric nature. This is unfortunate since these image features are…
Automated breast cancer detection via computer vision techniques is challenging due to the complex nature of breast tissue, the subtle appearance of cancerous lesions, and variations in breast density. Mainstream techniques primarily focus…
This paper explores the automated analysis of palmar features using machine learning techniques. We present a computer vision pipeline that extracts key characteristics from palm images, such as principal line structures, texture, and shape…
Accurate reconstruction of missing morphological indicators of a city is crucial for urban planning and data-driven analysis. This study presents the spatial-morphological (SM) imputer tool, which combines data-driven morphological…
Feature selection of high-dimensional labeled data with limited observations is critical for making powerful predictive modeling accessible, scalable, and interpretable for domain experts. Spectroscopy data, which records the interaction…
This paper discusses an approach, based on the subsampling boostrap and FDR control, to improve the stability of feature selection. It furthermore presents the finite sample distribution of the correlation coefficient recently proposed by…
Local spectral similarity (LSS) algorithm has been developed for detecting homogeneous areas and edges in hyperspectral images (HSIs). The proposed algorithm transforms the 3-D data cube (within a spatial window) into a spectral similarity…
One of the founding paradigms of machine learning is that a small number of variables is often sufficient to describe high-dimensional data. The minimum number of variables required is called the intrinsic dimension (ID) of the data.…
We propose a new approach for clustering DNA features using array CGH data from multiple tumor samples. We distinguish data-collapsing: joining contiguous DNA clones or probes with extremely similar data into regions, from clustering:…
Radiomics analysis has emerged as a promising approach for extracting quantitative features from medical images to aid in cancer diagnosis and treatment. However, radiomics research currently lacks standardization, and radiomics features…
In this paper, we propose a methodology for extracting molecular tumor biomarkers from hyperspectral imaging (HSI), an emerging technology for intraoperative tissue assessment. To achieve this, we employ spectral unmixing, allowing to…
The effective management of brain tumors relies on precise typing, subtyping, and grading. This study advances patient care with findings from rigorous multiple instance learning experimentations across various feature extractors and…
Previous studies on computer aided detection/diagnosis (CAD) in 4D breast magnetic resonance imaging (MRI) regard lesion detection, segmentation and characterization as separate tasks, and typically require users to manually select 2D MRI…
This article addresses extraction of physically meaningful information from STEM EELS and EDX spectrum-images using methods of Multivariate Statistical Analysis. The problem is interpreted in terms of data distribution in a…
The diagnosis and segmentation of tumors using any medical diagnostic tool can be challenging due to the varying nature of this pathology. Magnetic Reso- nance Imaging (MRI) is an established diagnostic tool for various diseases and…
Molecular dynamics (MD) simulations have been widely applied to study macromolecules including proteins. However, high-dimensionality of the datasets produced by simulations makes it difficult for thorough analysis, and further hinders a…
Accelerator mass spectrometry (AMS) is a widely-used technique with multiple applications, including geology, molecular biology and archeology. In order to achieve a high dynamic range, AMS requires tandem accelerators and large magnets,…
In this study, we present a method of pattern mining based on network theory that enables the identification of protein structures or complexes from synthetic volume densities, without the knowledge of predefined templates or human biases…
In digital pathology, both detection and classification of cells are important for automatic diagnostic and prognostic tasks. Classifying cells into subtypes, such as tumor cells, lymphocytes or stromal cells is particularly challenging.…
The application of information theory in medical imaging, particularly in magnetic resonance imaging (MRI), offers powerful quantitative tools for analyzing structural differences in brain tissues. This study utilizes mutual information…