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A widely used approach for extracting information from gene expression data employ the construction of a gene co-expression network and the subsequent application of algorithms that discover network structure. In particular, a common goal…

Genomics · Quantitative Biology 2024-08-20 Niloofar Aghaieabiane , Ioannis Koutis

Clustering under pairwise constraints is an important knowledge discovery tool that enables the learning of appropriate kernels or distance metrics to improve clustering performance. These pairwise constraints, which come in the form of…

Machine Learning · Computer Science 2022-03-24 Benedikt Boecking , Vincent Jeanselme , Artur Dubrawski

Molecular sequence analysis is crucial for comprehending several biological processes, including protein-protein interactions, functional annotation, and disease classification. The large number of sequences and the inherently complicated…

Genomics · Quantitative Biology 2025-10-10 Sarwan Ali , Prakash Chourasia , Bipin Koirala , Murray Patterson

Clustering is a widely used unsupervised learning method for finding structure in the data. However, the resulting clusters are typically presented without any guarantees on their robustness; slightly changing the used data sample or…

Machine Learning · Statistics 2017-01-02 Andreas Henelius , Kai Puolamäki , Henrik Boström , Panagiotis Papapetrou

To cluster data is to separate samples into distinctive groups that should ideally have some cohesive properties. Today, numerous clustering algorithms exist, and their differences lie essentially in what can be perceived as ``cohesive…

Machine Learning · Statistics 2025-05-08 Louis Ohl , Pierre-Alexandre Mattei , Frédéric Precioso

We study the clustering problem for mixtures of bounded covariance distributions, under a fine-grained separation assumption. Specifically, given samples from a $k$-component mixture distribution $D = \sum_{i =1}^k w_i P_i$, where each $w_i…

Machine Learning · Computer Science 2023-12-20 Ilias Diakonikolas , Daniel M. Kane , Jasper C. H. Lee , Thanasis Pittas

This work aims at improving the quality of structural variant prediction from the mapped reads of a sequenced genome. We suggest a new model based on cluster editing in weighted graphs and introduce a new heuristic algorithm that allows to…

Data Structures and Algorithms · Computer Science 2013-10-15 Thomas Bellitto , Tobias Marschall , Alexander Schönhuth , Gunnar W. Klau

Clustering traditionally aims to reveal a natural grouping structure within unlabeled data. However, this structure may not always align with users' preferences. In this paper, we propose a personalized clustering method that explicitly…

Machine Learning · Computer Science 2025-05-28 Xiwen Geng , Suyun Zhao , Yixin Yu , Borui Peng , Pan Du , Hong Chen , Cuiping Li , Mengdie Wang

Clustering is a popular data mining technique that aims to partition an input space into multiple homogeneous regions. There exist several clustering algorithms in the literature. The performance of a clustering algorithm depends on its…

Human-Computer Interaction · Computer Science 2020-08-20 Sudip Poddar , Anirban Mukhopadhyay

Clustering provides a common means of identifying structure in complex data, and there is renewed interest in clustering as a tool for the analysis of large data sets in many fields. A natural question is how many clusters are appropriate…

Data Analysis, Statistics and Probability · Physics 2007-05-23 Susanne Still , William Bialek

We develop a novel algorithm, Predictive Hierarchical Clustering (PHC), for agglomerative hierarchical clustering of current procedural terminology (CPT) codes. Our predictive hierarchical clustering aims to cluster subgroups, not…

Methodology · Statistics 2017-08-03 Elizabeth C. Lorenzi , Stephanie L. Brown , Zhifei Sun , Katherine Heller

Many community detection algorithms are inherently stochastic, leading to variations in their output depending on input parameters and random seeds. This variability makes the results of a single run of these algorithms less reliable.…

Social and Information Networks · Computer Science 2025-02-25 Yasamin Tabatabaee , Eleanor Wedell , Minhyuk Park , Tandy Warnow

Genome wide comparisons between enteric bacteria yield large sets of conserved putative regulatory sites on a gene by gene basis that need to be clustered into regulons. Using the assumption that regulatory sites can be represented as…

Biological Physics · Physics 2009-11-07 Erik van Nimwegen , Mihaela Zavolan , Nikolaus Rajewsky , Eric D. Siggia

Clustering ensemble has emerged as an important research topic in the field of machine learning. Although numerous methods have been proposed to improve clustering quality, most existing approaches overlook the need for interpretability in…

Machine Learning · Computer Science 2025-06-09 Hang Lv , Lianyu Hu , Mudi Jiang , Xinying Liu , Zengyou He

Clustering is a popular machine learning technique for data mining that can process and analyze datasets to automatically reveal sample distribution patterns. Since the ubiquitous categorical data naturally lack a well-defined metric space…

Machine Learning · Computer Science 2025-09-01 Yiqun Zhang , Mingjie Zhao , Hong Jia , Yang Lu , Mengke Li , Yiu-ming Cheung

Research on cluster analysis for categorical data continues to develop, with new clustering algorithms being proposed. However, in this context, the determination of the number of clusters is rarely addressed. In this paper, we propose a…

Methodology · Statistics 2014-09-29 Cláudia Silvestre , Margarida G. M. S. Cardoso , Mário A. T. Figueiredo

Algorithms for clustering points in metric spaces is a long-studied area of research. Clustering has seen a multitude of work both theoretically, in understanding the approximation guarantees possible for many objective functions such as…

Data Structures and Algorithms · Computer Science 2019-05-27 Maria-Florina Balcan , Travis Dick , Colin White

While traditional research on text clustering has largely focused on grouping documents by topic, it is conceivable that a user may want to cluster documents along other dimensions, such as the authors mood, gender, age, or sentiment.…

Information Retrieval · Computer Science 2014-01-22 Sajib Dasgupta , Vincent Ng

Finding clusters of well-connected nodes in a graph is an extensively studied problem in graph-based data analysis. Because of its many applications, a large number of distinct graph clustering objective functions and algorithms have…

Social and Information Networks · Computer Science 2019-03-14 Nate Veldt , David F. Gleich , Anthony Wirth

State-of-the-art clustering algorithms use heuristics to partition the feature space and provide little insight into the rationale for cluster membership, limiting their interpretability. In healthcare applications, the latter poses a…

Machine Learning · Statistics 2018-12-04 Dimitris Bertsimas , Agni Orfanoudaki , Holly Wiberg
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