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The experimental achievements and the current program with the LPCTrap device installed at the LIRAT beam line of the SPIRAL1-GANIL facility are presented. The device is dedicated to the study of the weak interaction at low energy by means…

Nuclear Experiment · Physics 2013-07-15 G. Ban , D. Durand , X. Fléchard , E. Liénard , O. Naviliat-Cuncic

This study presents a proof-of-concept for a novel Bayesian inverse method in a one-dimensional setting, aimed at proton beam therapy treatment verification. Our methodology is predicated on a hypothetical scenario wherein strategically…

Applications · Statistics 2023-11-21 Alexander M. G. Cox , Laura Hattam , Andreas E. Kyprianou , Tristan Pryer

We study the inverse problem of localization (imaging) of a laser beam from measurements of the intensity of light scattered off-axis by a Poisson cloud of small particles. Starting from the wave equation, we analyze the microscopic…

Data Analysis, Statistics and Probability · Physics 2017-07-27 Liliana Borcea , Josselin Garnier

Particle therapy is an established method to treat deep-seated tumours using accelerator-produced ion beams. For treatment planning, the precise knowledge of the relative stopping power (RSP) within the patient is vital. Conversion errors…

Two full rotating gantry with different nozzles (Multipurpose nozzle with MLC, Scanning Dedicated nozzle) with conventional cyclotron system is installed and under commissioning for various proton treatment options at Samsung Medical Center…

In the context of particle therapy monitoring, we are developing a gamma-ray detector to determine the ion range in vivo from the measurement of particle time-of-flight. For this application, a beam monitor capable to tag in time the…

We recently proposed a new approach for the real-time monitoring of particle therapy treatments with the goal of achieving high sensitivities on the particle range measurement already at limited counting statistics. This method extends the…

The first purpose of this paper is to shed some new light on the old question of selecting the number of beams in intensity-modulated radiation therapy (IMRT). The second purpose is to illuminate the related issue of discrete static beam…

Medical Physics · Physics 2015-05-14 Thomas Bortfeld

Background: Ultra-high dose rate proton therapy shows promise in tissue sparing by enhancing therapeutic ratio through the FLASH effect. In radiotherapy, accurate in vivo dosimetry is crucial for quality assurance, but remains challenging…

We present an application of a quadrature phase interferometer to the measurement of the angular position of a parallel laser beam with interferometric precision. In our experimental realization we reach a resolution of 6.8e-10 rad (1.4e-4…

Instrumentation and Detectors · Physics 2007-10-16 Pierdomenico Paolino , Ludovic Bellon

We describe here a compact gantry system, when the lying patient is slowly moved in horizontal and vertical directions in accordance with rotation of transport channel around its axis so that the region, irradiated from different…

Accelerator Physics · Physics 2016-12-13 Alexander Mikhailichenko

Fast procedures for the beam quality assessment and for the monitoring of beam energy modulations during the irradiation are among the most urgent improvements in particle therapy. Indeed, the online measurement of the particle beam energy…

Aligning beamlines at synchrotron light sources is a high-dimensional, expensive-to-sample optimization problem, as beams are focused using a series of dynamic optical components. Bayesian Optimization is an efficient machine learning…

Accelerator Physics · Physics 2024-08-14 Megha R. Narayanan , Thomas W. Morris

Laser-electron beam collisions that aim to generate electron-positron pairs require laser intensities $I \gtrsim 10^{21} ~\textrm{W/cm}^2$, which can be obtained by focusing a 1-PW optical laser to a spot smaller than 10 $~\mu$m. Spatial…

Plasma Physics · Physics 2021-11-17 Óscar Amaro , Marija Vranic

Carbon ion beam radiotherapy enables a very localised dose deposition. However, already small changes in the patient geometry or positioning errors can significantly distort the dose distribution. A live monitoring system of the beam…

The intra-beam repulsions play a significant role in determining the performances of free-electron devices when an high brilliance of the beam is required. The transversal and longitudinal spread of the beam, its energy and density are…

Plasma Physics · Physics 2012-10-29 B. Paroli

Focused ion beams are indispensable tools in the semiconductor industry because of their ability to image and modify structures at the nanometer length scale. Here we report on performance predictions of a new type of focused ion beam based…

Accelerator Physics · Physics 2015-01-27 G. ten Haaf , S. H. W. Wouters , S. B. van der Geer , E. J. D. Vredenbregt , P. H. A. Mutsaers

We propose and analyze in detail a method to measure the in-air spatial spread parameter of clinical electron beams. Measurements are performed at the center of the beam and below the adjustable collimators sited in asymmetrical…

Medical Physics · Physics 2009-10-31 M. Vilches , J. C. Zapata , D. Guirado , D. Fernández , D. Burgos , A. M. Lallena

Particle beams focused to micrometer-sized spots play a crucial role in forefront research using low-energy positrons. Their expedient and wide application, however, requires highly-resolved, fast beam diagnostics. We have developed two…

The photoelectron spectroscopy beamline at National Synchrotron Radiation Laboratory (NSRL) is equipped with a spherical grating monochromator with the included angle of 174 deg. Three gratings with line density of 200, 700 and 1200…

Instrumentation and Detectors · Physics 2015-06-15 Chaoyang Li , Hanbin Pan , Shen Wen , Congyuan Pan , Ning An , Xuewei Du , Junfa Zhu , Qiuping Wang