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Related papers: Droplet Formation via Solvent Shifting in a Microf…

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Solvent exchange is a process involving mixing between a good solvent with dissolved solute and a poor solvent. The process creates local oversaturation which causes the nucleation of minute solute droplets. Such ternary systems on a…

Fluid Dynamics · Physics 2022-06-07 You-An Lee , Chao Sun , Sander G. Huisman , Detlef Lohse

In this article, we have developed a computational model to determine the droplet formation regime and its transition in a square microfluidic flow-focusing device that eventually dictate the droplet shape, size, and its formation…

Fluid Dynamics · Physics 2025-10-28 Somasekhara Goud Sontti , Arnab Atta

The design of strategies to generate efficient mixing is crucial for a variety of applications, particularly digital microfluidic devices that use small "discrete" fluid volumes (droplets) as fluid carriers and microreactors. In recent…

Chaotic Dynamics · Physics 2008-09-03 R. Chabreyrie , D. Vainchtein , C. Chandre , P. Singh , N. Aubry

How liquid transport occurs in confined spaces is relevant to many industrial and lab-scale processes, ranging from enhanced oil recovery to drug delivery systems. In this work, we investigate propelling microdroplets that form from…

Soft Condensed Matter · Physics 2021-06-15 Gilmar F. Arends , John M. Shaw , Xuehua Zhang

In this work, we investigate crystallization from droplets formed on micro-patterned surfaces. By solvent exchange in a micro-chamber, a ternary solution consisting of a model compound beta-alanine, water, and isopropanol, was displaced by…

Soft Condensed Matter · Physics 2021-04-16 Howon Choi , Zixiang Wei , Jae Bem You , Huaiyu Yang , Xuehua Zhang

In this work, we used a coupled level set and volume of fluid (CLSVOF) computational method for studying the generation of microdroplets in a two dimensional circular co-flow microfluidic device. The fundamental understanding of shear…

Fluid Dynamics · Physics 2025-07-17 Manohar Jammula , Somasekhara Goud Sontti

Droplet formation in oiling-out crystallization has important implication for separation and purification of pharmaceutical active ingredients by using an antisolvent. In this work, we report the crystallization processes of oiling-out…

Soft Condensed Matter · Physics 2020-09-14 Xuehua Zhang , Zixiang Wei , Howon Choi , Hao Hao , Huaiyu Yang

Droplet-based microfluidics turned out to be an efficient and adjustable platform for digital analysis, encapsulation of cells, drug formulation, and polymerase chain reaction. Typically, for most biomedical applications, the handling of…

Soft Condensed Matter · Physics 2018-01-30 Enrico Chiarello , Anupam Gupta , Giampaolo Mistura , Mauro Sbragaglia , Matteo Pierno

The migration characteristics of a suspended deformable droplet in a parallel plate microchannel is studied, both analytically and numerically, under the combined influence of a constant temperature gradient in the transverse direction and…

Fluid Dynamics · Physics 2017-05-05 Sayan Das , Shubhadeep Mandal , Suman Chakraborty

Droplet-based microfluidics has emerged as a powerful technology for the miniaturization and automation of biochemical assays. The replacement of surfactants by nanoparticles as interfacial stabilizers has gained increasing interest.…

Soft Condensed Matter · Physics 2019-06-21 Laura Andreina Chacon Orellana , Jean-Christophe Baret

This study investigates the hydrodynamics of droplet formation in a T-shaped cylindrical microfluidic device using micro-PIV experiments and CFD simulations. Devices of 150 micro-m internal diameter were fabricated from PDMS via a…

Fluid Dynamics · Physics 2026-03-04 Pratibha Dogra , Ram Prakash Bharti , Gaurav Sharma

We present a mesoscale representation of near-contact interactions between colliding droplets which permits to reach up to the scale of full microfluidic devices, where such droplets are produced. The method is demonstrated for the case of…

Computational Physics · Physics 2020-06-23 Andrea Montessori , Marco Lauricella , Adriano Tiribocchi , Sauro Succi

The ability to transfer microdroplets between fluid phases offers numerous advantages in various fields, enabling better control, manipulation, and utilization of small volumes of fluids in pharmaceutical formulations, microfluidics, and…

Fluid Dynamics · Physics 2024-03-26 Haichang Yang , Binglin Zeng , Qiuyun Lu , Yaowen Xing , Xiahui Gui , Yijun Cao , Ben Bin Xu , Xuehua Zhang

The present study deals with the numerical as well as asymptotic analysis of the electrohydrodynamic interaction between two deformable droplets in a confined shear flow. Considering both the phases as leaky dielectric, we have performed…

Fluid Dynamics · Physics 2019-03-27 Somnath Santra , Diptendu Sen , Sayan Das , Suman Chakraborty

Dripping, jetting and tip streaming have been studied up to a certain point separately by both fluid mechanics and microfluidics communities, the former focusing on fundamental aspects while the latter on applications. Here, we intend to…

Fluid Dynamics · Physics 2020-06-22 Jose M. Montanero , Alfonso M. Ganan-Calvo

A three-dimensional, volume-of-fluid (VOF) based CFD model is presented to investigate droplet formation in a microfluidic T-junction. Genesis of Newtonian droplets in non-Newtonian liquid is numerically studied and characterized in three…

Fluid Dynamics · Physics 2025-10-09 Somasekhara Goud Sontti , Arnab Atta

Three-dimensional, time-dependent direct simulations of step emulsification micro-devices highlight two essential mechanisms for droplet formation: first, the onset of an adverse pressure gradient driving a back-flow of the continuous phase…

Computational Physics · Physics 2020-06-22 Andrea Montessori , Marco Lauricella , Sauro Succi , Elad Stolovicki , David A. Weitz

Step-emulsification is a microfluidic technique for droplet generation which relies on the abrupt decrease of confinement of a liquid filament surrounded by a continuous phase. A striking feature of this geometry is the transition between…

Fluid Dynamics · Physics 2014-09-19 M. Hein , S. Afkhami , R. Seemann , L. Kondic

We have developed a coupled level set and volume of fluid-based computational fluid dynamics model to analyze the droplet formation mechanism in a square flow-focusing microchannel. We demonstrate a flexible manipulation of droplet…

Fluid Dynamics · Physics 2025-10-09 Somasekhara Goud Sontti , Arnab Atta

Hypothesis: Immiscible liquids are commonly used to achieve unique functions in many applications, where the breakup of compound droplets in airflow is an important process. Due to the existence of the liquid-liquid interface, compound…

Fluid Dynamics · Physics 2023-12-27 Zhikun Xu , Yue Zhang , Tianyou Wang , Zhizhao Che
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