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Understanding the behavior of biomolecules such as proteins requires understanding the critical influence of the surrounding fluid (solvent) environment--water with mobile salt ions such as sodium. Unfortunately, for many studies, fully…

Soft Condensed Matter · Physics 2015-05-27 J. P. Bardhan , D. A. Tejani , N. S. Wieckowski , A. Ramaswamy , M. G. Knepley

This paper tests a dielectric model for variation of hydration free energy with geometry of complex solutes in water. It works out some basic aspects of the theory of boundary integral methods for these problems. One aspect of the…

chem-ph · Physics 2008-02-03 L. R. Pratt , G. J. Tawa , G. Hummer , A. E. Garcia , S. A. Corcelli

In this chapter we review the electrostatic properties of charged membranes in aqueous solutions, with or without added salt, employing simple physical models. The equilibrium ionic profiles close to the membrane are governed by the…

Soft Condensed Matter · Physics 2023-01-05 Tomer Markovich , David Andelman , Rudi Podgornik

For charged systems in heterogeneous dielectric media, a key obstacle for molecular dynamics (MD) simulations is the need to solve the Poisson equation in the media. This obstacle can be bypassed using MD methods that treat the local…

Soft Condensed Matter · Physics 2013-09-27 Vikram Jadhao , Francisco J. Solis , Monica Olvera de la Cruz

Cellular electrophysiology is often modeled using the cable equations. The cable model can only be used when ionic concentration effects and three dimensional geometry effects are negligible. The Poisson model, in which the electrostatic…

Neurons and Cognition · Quantitative Biology 2009-01-27 Yoichiro Mori

The problem of the one dimensional electro-diffusion of ions in a strong binary electrolyte is considered. In such a system the solute dissociates completely into two species of ions with unlike charges. The mathematical description…

Chemical Physics · Physics 2012-03-28 Sandip Ghosal , Zhen Chen

The description of a conducting medium in thermal equilibrium, such as an electrolyte solution or a plasma, involves nonlinear electrostatics, a subject rarely discussed in the standard electricity and magnetism textbooks. We consider in…

Chemical Physics · Physics 2018-08-01 C. G. Gray , P. J. Stiles

We implement a well-established concept to consider dispersion effects within a Poisson-Boltzmann approach of continuum solvation of proteins. The theoretical framework is particularly suited for boundary element methods. Free parameters…

Biological Physics · Physics 2007-11-28 Parimal Kar , Max Seel , Ulrich H. E. Hansmann , Siegfried Hoefinger

Poisson-Boltzmann theory is the cornerstone for soft matter electrostatics. We provide novel exact analytical solutions to this non-linear mean-field approach, for the diffuse layer of ions in the vicinity of a planar or a cylindrical…

Soft Condensed Matter · Physics 2020-01-29 L. Samaj , E. Trizac

In a continuum model of the solvation of charged molecules in an aqueous solvent, the classical Poisson-Boltzmann (PB) theory is generalized to include the solute point charges and the dielectric boundary that separates the high-dielectric…

Optimization and Control · Mathematics 2021-09-29 Bo Li , Zhengfang Zhang , Shenggao Zhou

Treating water as a linearly responding dielectric continuum on molecular length scales allows very simple estimates of solvation structure and thermodynamics for charged and polar solutes. While this approach can successfully account for…

Statistical Mechanics · Physics 2021-07-07 Stephen J. Cox , Kranthi K. Mandadapu , Phillip L. Geissler

The Poisson-Boltzmann equation for a strongly charged plate inside a generic charge-asymmetric electrolyte is solved using the method of asymptotic matching. Both near field and far field asymptotic behaviors of the potential are…

Soft Condensed Matter · Physics 2015-06-05 Ming Han , Xiangjun Xing

We propose a model for the calculation of renormalized charges and osmotic properties of mixtures of highly charged colloidal particles. The model is a generalization of the cell model and the notion of charge renormalization as introduced…

Soft Condensed Matter · Physics 2009-03-19 Aldemar Torres , Gabriel Tellez , Rene van Roij

Numerical solution of the Poisson equation in metallic enclosures, open at one or more ends, is important in many practical situations such as High Power Microwave (HPM) or photo-cathode devices. It requires imposition of a suitable…

Computational Physics · Physics 2015-10-16 Debabrata Biswas , Gaurav Singh , Raghwendra Kumar

We consider the Poisson-Boltzmann equation in a periodic cell, representative of a porous medium. It is a model for the electrostatic distribution of $N$ chemical species diluted in a liquid at rest, occupying the pore space with charged…

Analysis of PDEs · Mathematics 2015-04-24 Gregoire Allaire , Jean-Francois Dufreche , Andro Mikelic , Andrey Piatnitski

Modeling the chemical, electric, and thermal transport as well as phase transitions and the accompanying mesoscale microstructure evolution within a material in an electronic device setting involves the solution of partial differential…

Numerical Analysis · Mathematics 2024-09-26 Xiaofeng Xu , Lian Zhang , Yin Shi , Long-Qing Chen , Jinchao Xu

We study the boundary layer solution to singular perturbation problems involving Poisson-Boltzmann (PB) type equations with a small parameter $\epsilon$ in general bounded smooth domains (including multiply connected domains) under the…

Analysis of PDEs · Mathematics 2025-06-27 Jhih-Hong Lyu , Tai-Chia Lin

The energy functional, the governing partial differential equation(s) (PDE), and the boundary conditions need to be consistent with each other in a modeling system. In electrolyte solution study, people usually use a free energy form of an…

Soft Condensed Matter · Physics 2017-02-07 Xuejiao Liu , Yu Qiao , Benzhuo Lu

This work considers charged systems described by the modified Poisson--Nernst--Planck (PNP) equations, which incorporate ionic steric effects and the Born solvation energy for dielectric inhomogeneity. Solving the steady-state modified PNP…

Numerical Analysis · Mathematics 2025-06-04 Zhonghua Qiao , Zhenli Xu , Qian Yin , Shenggao Zhou

Electrostatic correlations and variable permittivity of electrolytes are essential for exploring many chemical and physical properties of interfaces in aqueous solutions. We propose a continuum electrostatic model for the treatment of these…

Soft Condensed Matter · Physics 2015-06-23 Manman Ma , Zhenli Xu
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