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The variation in DNA copy number carries information on the modalities of genome evolution and misregulation of DNA replication in cancer cells; its study can be helpful to localize tumor suppressor genes, distinguish different populations…

Methodology · Statistics 2012-03-20 Zhongyang Zhang , Kenneth Lange , Chiara Sabatti

We propose a novel method called deep convolutional decision jungle (CDJ) and its learning algorithm for image classification. The CDJ maintains the structure of standard convolutional neural networks (CNNs), i.e. multiple layers of…

Computer Vision and Pattern Recognition · Computer Science 2018-05-21 Seungryul Baek , Kwang In Kim , Tae-Kyun Kim

Cut generation and lifting are key components for the performance of state-of-the-art mathematical programming solvers. This work proposes a new general cut-and-lift procedure that exploits the combinatorial structure of 0-1 problems via a…

Optimization and Control · Mathematics 2022-01-28 Margarita P. Castro , Andre A. Cire , J. Christopher Beck

Divide-and-conquer is a general strategy to deal with large scale problems. It is typically applied to generate ensemble instances, which potentially limits the problem size it can handle. Additionally, the data are often divided by random…

Machine Learning · Computer Science 2019-11-19 Ke Alexander Wang , Xinran Bian , Pan Liu , Donghui Yan

Exchange type chromosome aberrations (ETCAs) are rearrangements of the genome that occur when chromosomes break and the resulting fragments rejoin with other fragments from other chromosomes. ETCAs are commonly observed in cancer cells and…

Applications · Statistics 2014-06-03 Javier Arsuaga , Ido Heskia , Serkan Hosten , Tatsiana Maskalevich

Array-Based Comparative Genomic Hybridization (aCGH) is a method used to search for genomic regions with copy numbers variations. For a given aCGH profile, one challenge is to accurately segment it into regions of constant copy number.…

Quantitative Methods · Quantitative Biology 2009-10-08 Kevin Bleakley , Jean-Philippe Vert

As a powerful engine, vanilla convolution has promoted huge breakthroughs in various computer tasks. However, it often suffers from sample and content agnostic problems, which limits the representation capacities of the convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2022-11-14 Longbin Yan , Yunxiao Qin , Shumin Liu , Jie Chen

An iterative decoding algorithm for convolutional codes is presented. It successively processes $N$ consecutive blocks of the received word in order to decode the first block. A bound is presented showing which error configurations can be…

Information Theory · Computer Science 2009-08-07 H. Gluesing-Luerssen , U. Helmke , J. I. Iglesias Curto

With the rapid advancements in digital imaging systems and networking, low-cost hand-held image capture devices equipped with network connectivity are becoming ubiquitous. This ease of digital image capture and sharing is also accompanied…

Multimedia · Computer Science 2019-06-20 Vinay Verma , Nikita Agarwal , Nitin Khanna

Genome rearrangement distances are an established method in genome comparison. Works in this area may include various rearrangement operations representing large-scale mutations, gene orientation information, the number of nucleotides in…

Data Structures and Algorithms · Computer Science 2026-01-01 Gabriel Siqueira , Alexsandro Oliveira Alexandrino , Zanoni Dias

We live in a period where bio-informatics is rapidly expanding, a significant quantity of genomic data has been produced as a result of the advancement of high-throughput genome sequencing technology, raising concerns about the costs…

Quantitative Methods · Quantitative Biology 2023-03-10 Mehedi Hasan Sarkar , Adnan Ferdous Ashrafi

We study a class of integer bilevel programs with second-order cone constraints at the upper-level and a convex-quadratic objective function and linear constraints at the lower-level. We develop disjunctive cuts (DCs) to separate…

Optimization and Control · Mathematics 2023-06-06 Elisabeth Gaar , Jon Lee , Ivana Ljubić , Markus Sinnl , Kübra Tanınmış

A novel mechanism for cell differentiation is proposed, based on the dynamic clustering in a globally coupled chaotic system. A simple model with metabolic reaction, active transport of chemicals from media, and cell division is found to…

adap-org · Physics 2009-10-22 Kunihiko Kaneko , Tetsuya Yomo

Goulden and Jackson first introduced the cut-and-join operator. The cut-and-join is widely used in studying the Hurwitz number and many other topological recursion problems. Mironov, Morosov and Natanzon give a more general construction and…

Combinatorics · Mathematics 2020-10-22 Hao Sun

An alternative foundation for 2-categories is explored by studying graph-theoretically a partial operation on 2-cells named juncture, which can replace vertical and horizontal composition. Juncture is a generalized vertical composition of…

Combinatorics · Mathematics 2015-05-07 Kosta Dosen , Zoran Petric

We call change-point problem (CPP) the identification of changes in the probabilistic behavior of a sequence of observations. Solving the CPP involves detecting the number and position of such changes. In genetics the study of how and what…

Applications · Statistics 2017-01-18 Murilo S. Pinheiro , Benilton S. Carvalho , Aluísio S. Pinheiro

Using the precursor map in AdS/CFT, the renormalization group cutoff function is mapped to the dual theory. The resulting flow equations on the two sides of the duality are compared.

High Energy Physics - Theory · Physics 2019-09-04 Farhad Ardalan

In this paper we present the construction of explicit quasi-isomorphisms that compute the cyclic homology and periodic cyclic homology of crossed-product algebras associated with (discrete) group actions. In the first part we deal with…

K-Theory and Homology · Mathematics 2017-09-26 Raphael Ponge

We propose DualConvMesh-Nets (DCM-Net) a family of deep hierarchical convolutional networks over 3D geometric data that combines two types of convolutions. The first type, geodesic convolutions, defines the kernel weights over mesh surfaces…

Computer Vision and Pattern Recognition · Computer Science 2020-04-03 Jonas Schult , Francis Engelmann , Theodora Kontogianni , Bastian Leibe

Clusters of genes that have evolved by repeated segmental duplication present difficult challenges throughout genomic analysis, from sequence assembly to functional analysis. Improved understanding of these clusters is of utmost importance,…

Machine Learning · Computer Science 2010-01-25 Tomáš Vinař , Broňa Brejová , Giltae Song , Adam Siepel
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