English
Related papers

Related papers: Shaping Pulses to Control Bistable Biological Syst…

200 papers

The temporal shape of a pulse in transcranial magnetic stimulation (TMS) influences which neuron populations are activated preferentially as well as the strength and even direction of neuromodulation effects. Furthermore, various pulse…

Medical Physics · Physics 2022-02-15 Z. Li , J. Zhang , A. V. Peterchev , S. M. Goetz

Symbolic approaches to the control design over complex systems employ the construction of finite-state models that are related to the original control systems, then use techniques from finite-state synthesis to compute controllers…

Optimization and Control · Mathematics 2013-02-18 Majid Zamani , Peyman Mohajerin Esfahani , Rupak Majumdar , Alessandro Abate , John Lygeros

We uncover a dynamical entanglement transition in a monitored quantum system that is heralded by a local order parameter. Classically, chaotic systems can be stochastically controlled onto unstable periodic orbits and exhibit controlled and…

Disordered Systems and Neural Networks · Physics 2022-08-10 Thomas Iadecola , Sriram Ganeshan , J. H. Pixley , Justin H. Wilson

Efficient quantum control is a cornerstone for the advancement of quantum technologies, from computation to sensing and communications. Several approaches in quantum control, e.g. optimal control and inverse engineering, use pulse amplitude…

Quantum Physics · Physics 2025-11-21 Ivo S. Mihov , Nikolay V. Vitanov

This paper gives an overview of the use of control systems engineering in synthetic biology, motivated by applications such as cell therapy and cell fate reprogramming for regenerative medicine. A ubiquitous problem in these and other…

Systems and Control · Electrical Eng. & Systems 2026-01-29 Domitilla Del Vecchio

We study a mechanism for reliable switching in biomolecular signal-transduction cascades. Steady bistable states are created by system-size cooperative effects in populations of proteins, in spite of the fact that the phosphorylation-state…

Subcellular Processes · Quantitative Biology 2015-05-30 Eric Smith , Supriya Krishnamurthy , Walter Fontana , David Krakauer

The stability of complex networks, from power grids to biological systems, is crucial for their proper functioning. It is thus important to control such systems to maintain or restore their stability. Traditional approaches rely on…

Optimization and Control · Mathematics 2025-09-23 Yuzhen Qin , Fabio Pasqualetti , Danielle S. Bassett , Marcel van Gerven

The dynamics of an ensemble of bistable elements with global time-delayed coupling under the influence of noise is studied analytically and numerically. Depending on the noise level the system undergoes ordering transitions and demonstrates…

Statistical Mechanics · Physics 2009-11-10 D. Huber , L. S. Tsimring

This paper presents an algorithm for approximating certain types of dynamical systems given by a system of ordinary delay differential equations by a Boolean network model. Often Boolean models are much simpler to understand than complex…

Molecular Networks · Quantitative Biology 2011-05-10 Franziska Hinkelmann , Reinhard Laubenbacher

In this paper, the finite-time control and bumpless transfer control are investigated for switched systems under asynchronously switching. First, a class of dynamic output feedback controllers are designed to stabilize the switched system…

Systems and Control · Electrical Eng. & Systems 2024-07-29 Mo-Ran Liu , Zhen Wu , Xian Du , Zhongyang Fei

We consider a coupled bistable N-particle system driven by a Brownian noise, with a strong coupling corresponding to the synchronised regime. Our aim is to obtain sharp estimates on the metastable transition times between the two stable…

Probability · Mathematics 2010-03-01 Florent Barret , Anton Bovier , Sylvie Méléard

Birhythmicity arises in several physical, biological and chemical systems. Although, many control schemes are proposed for various forms of multistability, only a few exist for controlling birhythmicity. In this paper we investigate the…

Chaotic Dynamics · Physics 2016-11-09 Debabrata Biswas , Tanmoy Banerjee , Jürgen Kurths

Flexible modulation of temporal dynamics in neural sequences underlies many cognitive processes. For instance, we can adaptively change the speed of motor sequences and speech. While such flexibility is influenced by various factors such as…

Neurons and Cognition · Quantitative Biology 2025-04-15 Tomoki Kurikawa , Kunihiko Kaneko

We consider the problem of regulating by means of external control inputs the ratio of two cell populations. Specifically, we assume that these two cellular populations are composed of cells belonging to the same strain which embeds some…

Systems and Control · Computer Science 2020-03-18 Davide Salzano , Davide Fiore , Mario di Bernardo

We analyze the physical mechanisms leading either to synchronization or to the formation of spatio-temporal patterns in a lattice model of pulse-coupled oscillators. In order to make the system tractable from a mathematical point of view we…

Statistical Mechanics · Physics 2009-10-30 Albert Diaz-Guilera , Conrad J. Perez , Alex Arenas

Almost sure asymptotic stabilization of a discrete-time switched stochastic system is investigated. Information on the active operation mode of the switched system is assumed to be available for control purposes only at random time…

Systems and Control · Computer Science 2014-09-10 Ahmet Cetinkaya , Tomohisa Hayakawa

Multistability is an inseparable feature of many physical, chemical and biological systems which are driven far from equilibrium. In these nonequilibrium systems, stochastic dynamics often induces switching between distinct states on…

Adaptation and Self-Organizing Systems · Physics 2017-11-01 Guram Gogia , Justin Burton

Numerical simulations are used to study how fiber supercontinuum generation seeded by picosecond pulses can be actively controlled through the use of input pulse modulation. By carrying out multiple simulations in the presence of noise, we…

Optics · Physics 2009-11-13 G. Genty , J. M. Dudley , B. J. Eggleton

In this paper, we present a provably correct controller synthesis approach for switched stochastic control systems with metric temporal logic (MTL) specifications with provable probabilistic guarantees. We first present the stochastic…

Systems and Control · Electrical Eng. & Systems 2021-03-29 Zhe Xu , Yichen Zhang

We design realizable time-dependent semiclassical pulses to invert the population of a two-level system faster than adiabatically when the rotating-wave approximation cannot be applied. Different approaches, based on the counterdiabatic…

Quantum Physics · Physics 2016-01-06 S. Ibáñez , Yi-Chao Li , Xi Chen , J. G. Muga