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This letter is concerned with asymptotic analysis of a PDE model for motility of a eukaryotic cell on a substrate. This model was introduced in [1], where it was shown numerically that it successfully reproduces experimentally observed…

Analysis of PDEs · Mathematics 2016-04-12 Leonid Berlyand , Mykhailo Potomkin , Volodymyr Rybalko

We consider a system of two PDEs arising in modeling of motility of eukariotic cells on substrates. This system consists of the Allen-Cahn equation for the scalar phase field function coupled with another vectorial parabolic equation for…

Analysis of PDEs · Mathematics 2016-06-24 Leonid Berlyand , Volodymyr Rybalko , Mykhailo Potomkin

Phase-field models have recently had great success in describing the dynamic morphologies and motility of eukaryotic cells. In this work we investigate the minimal phase-field model introduced in [Berlyand, Potomkin, Rybalko (2017)].…

Cell Behavior · Quantitative Biology 2020-08-03 Nicolas Bolle , Matthew S. Mizuhara

This paper deals with the evolution equation of a curve obtained as the sharp interface limit of a non-linear system of two reaction-diffusion PDEs. This system was introduced as a phase-field model of (crawling) motion of eukaryotic cells…

Analysis of PDEs · Mathematics 2016-03-23 Matthew S. Mizuhara , Leonid Berlyand , Volodymyr Rybalko , Lei Zhang

We consider sharp interface asymptotics for a phase field model of two phase near spherical biomembranes involving a coupling between the local mean curvature and the local composition proposed by the first and second authors. The model is…

Analysis of PDEs · Mathematics 2020-12-24 Charles M. Elliott , Luke Hatcher , Björn Stinner

The use of continuum phase-field models to describe the motion of well-defined interfaces is discussed for a class of phenomena, that includes order/disorder transitions, spinodal decomposition and Ostwald ripening, dendritic growth, and…

Soft Condensed Matter · Physics 2009-10-31 K. R. Elder , Martin Grant , Nikolas Provatas , J. M. Kosterlitz

We study a non-linear and non-local evolution equation for curves obtained as the sharp interface limit of a phase-field model for crawling motion of eukaryotic cells on a substrate. We establish uniqueness of solutions to the sharp…

Analysis of PDEs · Mathematics 2017-03-03 Matthew S. Mizuhara , Peng Zhang

The sharp-interface limits of a phase-field model with a generalized Navier slip boundary condition for moving contact line problem are studied by asymptotic analysis and numerical simulations. The effects of the {mobility} number as well…

Analysis of PDEs · Mathematics 2019-11-12 Xianmin Xu , Yana Di , Haijun Yu

In this letter, we derive the sharp-interface limit of the Cahn-Hilliard-Biot equations using formal matched asymptotic expansions. We find that in each sub-domain, the quasi-static Biot equations are obtained with domain-specific material…

Analysis of PDEs · Mathematics 2024-12-06 Erlend Storvik , Carina Bringedal

In order to study the effect of cell elastic properties on the behavior of assemblies of motile cells, this paper describes an alternative to the cell phase field (CPF) \cite{Palmieri2015} we have previously proposed. The CPF is a…

Soft Condensed Matter · Physics 2019-05-23 Yony Bresler , Benoit Palmieri , Martin Grant

A new approach is developed to derive an analytical form for mobility corrections in phase-field models for pure material solidification. Similar to the thin interface limit approach (Karma and Rappel, 1996) it seeks to remove systematic…

Computational Physics · Physics 2019-05-09 Stephan Hubig , Raphael Schiedung , Ingo Steinbach

We discuss the sharp interface limit of a diffuse interface model for a two-phase flow of two partly miscible viscous Newtonian fluids of different densities, when a certain parameter \epsilon>0 related to the interface thickness tends to…

Analysis of PDEs · Mathematics 2012-12-24 Helmut Abels , Daniel Lengeler

We construct gradient structures for free boundary problems with nonlinear elasticity and study the impact of moving contact lines. In this context, we numerically analyze how phase-field models converge to certain sharp-interface limits…

Analysis of PDEs · Mathematics 2024-06-26 Leonie Schmeller , Dirk Peschka

We investigate the convergence of solutions of a recently proposed diffuse interface/phase field model for cell blebbing by means of matched asymptotic expansions. It is a biological phenomenon that increasingly attracts attention by both…

Analysis of PDEs · Mathematics 2023-02-10 Philipp Nöldner , Martin Burger , Harald Garcke

We investigate the asymptotic behavior of solutions for quasilinear parabolic equations in bounded intervals. In particular, we are concerned with a special class of solutions, called interface solutions, which exhibit e metastable…

Analysis of PDEs · Mathematics 2015-06-30 Linda De Cave , Marta Strani

We analyze a two-dimensional phase field model designed to describe the dynamics of crystalline grains. The phenomenological free energy is a functional of two order parameters. The first one reflects the orientational order while the…

Materials Science · Physics 2009-10-31 Alexander E. Lobkovsky , James A. Warren

In this work, the sharp interface limit of the degenerate Cahn-Hilliard equation (in two space dimensions) with a polynomial double well free energy and a quadratic mobility is derived via a matched asymptotic analysis involving…

Mathematical Physics · Physics 2015-07-10 Alpha Albert Lee , Andreas Münch , Endre Süli

We formulate a general shape and topology optimization problem in structural optimization by using a phase field approach. This problem is considered in view of well-posedness and we derive optimality conditions. We relate the diffuse…

Optimization and Control · Mathematics 2025-08-06 Luise Blank , Harald Garcke , Claudia Hecht , Christoph Rupprecht

We propose a sharp-interface model for a hyperelastic material consisting of two phases. In this model, phase interfaces are treated in the deformed configuration, resulting in a fully Eulerian interfacial energy. In order to penalize large…

Analysis of PDEs · Mathematics 2024-02-16 Katharina Brazda , Martin Kružík , Fabian Rupp , Ulisse Stefanelli

The finite solid-liquid interface width in phase field models results in non-equilibrium effects, including solute trapping. Prior phase field modeling has shown that this extra degree of freedom, when compared to sharp-interface models,…

Materials Science · Physics 2023-04-07 Arnab Mukherjee , James A. Warren , Peter W. Voorhees
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