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Coarse-grained modeling and efficient computer simulations are critical to the study of complex molecular processes with many degrees of freedom and multiple spatiotemporal scales. Variational implicit-solvent model (VISM) for biomolecular…

Chemical Physics · Physics 2022-10-26 Shuang Liu , Zirui Zhang , Li-Tien Cheng , Bo Li

Current supercomputers often have a heterogeneous architecture using both CPUs and GPUs. At the same time, numerical simulation tasks frequently involve multiphysics scenarios whose components run on different hardware due to multiple…

Computational Engineering, Finance, and Science · Computer Science 2024-12-10 Samuel Kemmler , Christoph Rettinger , Ulrich Rüde , Pablo Cuéllar , Harald Köstler

Graph neural networks are increasingly adopted in trigger systems for collider experiments, where strict latency and throughput constraints render deployment on embedded platforms challenging. As detectors move towards higher granularity,…

Hardware Architecture · Computer Science 2026-05-12 Marc Neu , Frank Baptist , Thomas Lobmaier , Fabio Papagno , Torben Ferber , Jürgen Becker

Fault-tolerant Quantum Processing Units (QPUs) promise to deliver exponential speed-ups in select computational tasks, yet their integration into modern deep learning pipelines remains unclear. In this work, we take a step towards bridging…

Quantum Physics · Physics 2026-05-19 Arthur G. Rattew , Po-Wei Huang , Naixu Guo , Lirandë Pira , Patrick Rebentrost

We present a MATLAB script which can use GPU acceleration to simulate a trapped ion interacting with a low-density cloud of atoms. This script, called atomiongpu.m, can massively parallelize MD simulations of trajectories of a trapped ion…

Atomic Physics · Physics 2025-09-17 Saajid Chowdhury , Jesús Pérez-Ríos

As deep neural networks (DNNs) become deeper, the training time increases. In this perspective, multi-GPU parallel computing has become a key tool in accelerating the training of DNNs. In this paper, we introduce a novel methodology to…

Numerical Analysis · Mathematics 2024-07-08 Chang-Ock Lee , Youngkyu Lee , Jongho Park

Modern deep learning applications urge to push the model inference taking place at the edge devices for multiple reasons such as achieving shorter latency, relieving the burden of the network connecting to the cloud, and protecting user…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-07-05 Leyuan Wang , Zhi Chen , Yizhi Liu , Yao Wang , Lianmin Zheng , Mu Li , Yida Wang

Our fully kinetic, implicit Particle-in-Cell (PIC) simulations of global magnetospheres on up to 32,768 of El Capitan's AMD Instinct MI300A Accelerated Processing Units (APUs) represent an unprecedented computational capability that…

Computational Engineering, Finance, and Science · Computer Science 2025-07-29 Stefano Markidis , Andong Hu , Ivy Peng , Luca Pennati , Ian Lumsden , Dewi Yokelson , Stephanie Brink , Olga Pearce , Thomas R. W. Scogland , Bronis R. de Supinski , Gian Luca Delzanno , Michela Taufer

We provide a preliminary study on utilizing GPU (Graphics Processing Unit) to accelerate computation for three simulation optimization tasks with either first-order or second-order algorithms. Compared to the implementation using only CPU…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-04-19 Jinghai He , Haoyu Liu , Yuhang Wu , Zeyu Zheng , Tingyu Zhu

With large-scale Integral Field Spectroscopy (IFS) surveys of thousands of galaxies currently under-way or planned, the astronomical community is in need of methods, techniques and tools that will allow the analysis of huge amounts of data.…

Instrumentation and Methods for Astrophysics · Physics 2015-12-22 Georgios Bekiaris , Karl Glazebrook , Christopher J. Fluke , Roberto Abraham

To respond to the need of efficient training and inference of deep neural networks, a plethora of domain-specific hardware architectures have been introduced, such as Google Tensor Processing Units and NVIDIA Tensor Cores. A common feature…

Data Structures and Algorithms · Computer Science 2020-07-10 Rezaul Chowdhury , Francesco Silvestri , Flavio Vella

This paper presents a heterogeneous adaptive mesh refinement (AMR) framework for efficient simulation of moderately stiff reactive problems. This framework features an elaborate subcycling-in-time algorithm along with a specialized…

Computational Physics · Physics 2025-06-04 Yuqi Wang , Yadong Zeng , Ralf Deiterding , Jianhan Liang

Computational tools for rigorously verifying the performance of large-scale machine learning (ML) models have progressed significantly in recent years. The most successful solvers employ highly specialized, GPU-accelerated branch and bound…

Machine Learning · Computer Science 2023-09-11 Samuel Chevalier , Ilgiz Murzakhanov , Spyros Chatzivasileiadis

This paper presents a novel, high-performance, graphical processing unit-based algorithm for efficiently solving two-dimensional linear programs in batches. The domain of two-dimensional linear programs is particularly useful due to the…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-02-14 John Charlton , Steve Maddock , Paul Richmond

Adaptive finite elements combined with geometric multigrid solvers are one of the most efficient numerical methods for problems such as the instationary Navier-Stokes equations. Yet despite their efficiency, computations remain expensive…

Numerical Analysis · Mathematics 2025-12-23 Manuel Liebchen , Robert Jendersie , Utku Kaya , Christian Lessig , Thomas Richter

Bayesian networks (BNs) are attractive, because they are graphical and interpretable machine learning models. However, exact inference on BNs is time-consuming, especially for complex problems. To improve the efficiency, we propose a fast…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-03-14 Jiantong Jiang , Zeyi Wen , Atif Mansoor , Ajmal Mian

Matrix decompositions are ubiquitous in machine learning, including applications in dimensionality reduction, data compression and deep learning algorithms. Typical solutions for matrix decompositions have polynomial complexity which…

Machine Learning · Computer Science 2024-03-13 Łukasz Struski , Paweł Morkisz , Przemysław Spurek , Samuel Rodriguez Bernabeu , Tomasz Trzciński

Purpose: Very fast Monte Carlo (MC) simulations of proton transport have been implemented recently on GPUs. However, these usually use simplified models for non-elastic (NE) proton-nucleus interactions. Our primary goal is to build a…

Medical Physics · Physics 2015-06-11 H. Wan Chan Tseung , J. Ma , C. Beltran

Neural representations have emerged as a new paradigm for applications in rendering, imaging, geometric modeling, and simulation. Compared to traditional representations such as meshes, point clouds, or volumes they can be flexibly…

Computer Vision and Pattern Recognition · Computer Science 2021-05-07 Julien N. P. Martel , David B. Lindell , Connor Z. Lin , Eric R. Chan , Marco Monteiro , Gordon Wetzstein

We implement a quantum optimal control algorithm based on automatic differentiation and harness the acceleration afforded by graphics processing units (GPUs). Automatic differentiation allows us to specify advanced optimization criteria and…

Quantum Physics · Physics 2017-04-19 Nelson Leung , Mohamed Abdelhafez , Jens Koch , David I. Schuster