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We review a coarse-graining strategy (multiblob approach) for polymer solutions in which groups of monomers are mapped onto a single atom (a blob) and effective blob-blob interactions are obtained by requiring the coarse-grained model to…

Soft Condensed Matter · Physics 2015-03-19 Giuseppe D'Adamo , Andrea Pelissetto , Carlo Pierleoni

We present a coarse-grained model for linear polymers with a tunable number of effective atoms (blobs) per chain interacting by intra- and inter-molecular potentials obtained at zero density. We show how this model is able to accurately…

Soft Condensed Matter · Physics 2012-07-17 Giuseppe D'Adamo , Andrea Pelissetto , Carlo Pierleoni

We extend our previously developed coarse-graining strategy for linear polymers with a tunable number n of effective atoms (blobs) per chain [D'Adamo et al., J. Chem. Phys. 137, 4901 (2012)] to polymer systems in thermal crossover between…

Soft Condensed Matter · Physics 2014-11-07 Giuseppe D'Adamo , Andrea Pelissetto , Carlo Pierleoni

We propose a systematic coarse-grained representation of block copolymers, whereby each block is reduced to a single ``soft blob'' and effective intra- as well as intermolecular interactions act between centres of mass of the blocks. The…

Soft Condensed Matter · Physics 2009-11-11 C. I. Addison , J. P. Hansen , V. Krakoviack , A. A. Louis

We discuss the reliability of integral-equation methods based on several commonly used closure relations in determining the phase diagram of coarse-grained models of soft-matter systems characterized by mutually interacting soft and…

Soft Condensed Matter · Physics 2015-10-28 Roberto Menichetti , Andrea Pelissetto , Giuseppe D'Adamo , Carlo Pierleoni

Structural and thermodynamic consistency of coarse-graining models across multiple length scales is essential for the predictive role of multi-scale modeling and molecular dynamic simulations that use mesoscale descriptions. Our approach is…

Soft Condensed Matter · Physics 2014-07-04 J. McCarty , A. J. Clark , J. Copperman , M. G. Guenza

Certain sequences of peptoid polymers (synthetic analogs of peptides) assemble into bilayer nanosheets via a nonequilibrium assembly pathway of adsorption, compression, and collapse at an air-water interface. As with other large-scale…

Biological Physics · Physics 2014-10-01 Thomas K. Haxton , Ranjan V. Mannige , Ronald N. Zuckermann , Stephen Whitelam

Soft nanocomposites represent both a theoretical and an experimental challenge due to the high number of the microscopic constituents that strongly influence the behaviour of the systems. An effective theoretical description of such systems…

Soft Condensed Matter · Physics 2016-12-14 Emanuele Locatelli , Barbara Capone , Christos N. Likos

We critically discuss and review the general ideas behind single- and multi-site coarse-grained (CG) models as applied to macromolecular solutions in the dilute and semi-dilute regime. We first consider single-site models with zero-density…

Soft Condensed Matter · Physics 2015-10-28 Giuseppe D'Adamo , Roberto Menichetti , Andrea Pelissetto , Carlo Pierleoni

We show how to coarse grain polymers in a good solvent as single particles, interacting with density-independent or density-dependent interactions. These interactions can be between the centres of mass, the mid-points or end-points of the…

Soft Condensed Matter · Physics 2009-11-07 A. A. Louis , P. G. Bolhuis , R. Finken , V. Krakoviack , E. J. Meijer , J. P. Hansen

We present an extension to the iterative Boltzmann inversion method to generate coarse-grained models with three-body intramolecular potentials that can reproduce correlations in structural distribution functions. The coarse-grained…

Computational Physics · Physics 2023-11-27 Jianlan Ye , Vipin Agrawal , Minghao Liu , Jing Hu , Jay Oswald

We systematically studied the validity and transferability of effective, coarse-grained, pair potentials in ultrasoft colloidal systems. We focused on amphiphilic dendrimers, macromolecules which can aggregate into clusters of overlapping…

Soft Condensed Matter · Physics 2018-02-01 Marta Montes-Saralegui , Gerhard Kahl , Arash Nikoubashman

Solutions of interacting linear polymers are mapped onto a system of ``soft'' spherical particles interacting via an effective pair potential. This coarse-graining reduces the individual monomer-level description to a problem involving only…

Soft Condensed Matter · Physics 2007-05-23 V. Krakoviack , J. P. Hansen , A. A. Louis

Several recently proposed semi--automatic and fully--automatic coarse--graining schemes for polymer simulations are discussed. All these techniques derive effective potentials for multi--atom units or super--atoms from atomistic…

Soft Condensed Matter · Physics 2007-05-23 Roland Faller

A coarse-graining strategy for dilute and semi-dilute solutions of interacting polymers, and of colloid polymer mixtures is briefly described. Monomer degrees of freedom are traced out to derive an effective, state dependent pair potential…

Soft Condensed Matter · Physics 2009-11-11 J. -P. Hansen , C. I. Addison , A. A. Louis

The structure of polyelectrolytes is highly sensitive to small changes in the interactions between its monomers. In particular, interactions mediated by counterions play a significant role, and are affected by both specific molecular…

Soft Condensed Matter · Physics 2020-02-03 Pauline Bacle , Marie Jardat , Virginie Marry , Guillaume Mériguet , Guillaume Batôt , Vincent Dahirel

Coupled length and time scales determine the dynamic behavior of polymers and underlie their unique viscoelastic properties. To resolve the long-time dynamics it is imperative to determine which time and length scales must be correctly…

Soft Condensed Matter · Physics 2016-02-16 K. Michael Salerno , Anupriya Agrawal , Dvora Perahia , Gary S. Grest

We consider a coarse-grained model in which polymers under good-solvent conditions are represented by soft spheres whose radii, which should be identified with the polymer radii of gyrations, are allowed to fluctuate. The corresponding pair…

Soft Condensed Matter · Physics 2012-06-19 Giuseppe D'Adamo , Andrea Pelissetto , Carlo Pierleoni

Coarse-grained models are a core computational tool in theoretical chemistry and biophysics. A judicious choice of a coarse-grained model can yield physical insight by isolating the essential degrees of freedom that dictate the…

Statistical Mechanics · Physics 2023-04-12 Shriram Chennakesavalu , David J. Toomer , Grant M. Rotskoff

We investigate and provide optimal sets of reaction coordinates for mixed pairs of molecules displaying polar, uniaxial, or spherical symmetry in two and three dimensions. These coordinates are non-redundant, i.e., they implicitly involve…

Statistical Mechanics · Physics 2017-05-01 Thomas Heinemann , Sabine H. L. Klapp
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