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Although timely sepsis diagnosis and prompt interventions in Intensive Care Unit (ICU) patients are associated with reduced mortality, early clinical recognition is frequently impeded by non-specific signs of infection and failure to detect…

Machine Learning · Computer Science 2018-06-28 Tony Wang , Tom Velez , Emilia Apostolova , Tim Tschampel , Thuy L. Ngo , Joy Hardison

Epilepsy is known to drastically alter brain dynamics during seizures (ictal periods), but its effects on background (non-ictal) brain dynamics remain poorly understood. To investigate this, we analyzed an in-house dataset of brain activity…

Topological Data Analysis (TDA) involves techniques of analyzing the underlying structure and connectivity of data. However, traditional methods like persistent homology can be computationally demanding, motivating the development of neural…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Dylan Peek , Matthew P. Skerritt , Siddharth Pritam , Stephan Chalup

Lung cancer is the number one cause of cancer deaths. Many early stage lung cancer patients have resectable tumors; however, their cardiopulmonary function needs to be properly evaluated before they are deemed operative candidates.…

Computers and Society · Computer Science 2017-07-27 Oleksiy Budilovsky , Golnaz Alipour , Andre Knoesen , Lisa Brown , Soheil Ghiasi

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Determining brain hemodynamics plays a critical role in the diagnosis and treatment of various cerebrovascular diseases. In this work, we put forth a physics-informed deep learning framework that augments sparse clinical measurements with…

Medical Physics · Physics 2021-08-27 Mohammad Sarabian , Hessam Babaee , Kaveh Laksari

With the growing adoption of AI-based systems across everyday life, the need to understand their decision-making mechanisms is correspondingly increasing. The level at which we can trust the statistical inferences made from AI-based…

Machine Learning · Statistics 2024-04-15 Adam Spannaus , Heidi A. Hanson , Lynne Penberthy , Georgia Tourassi

Lung Cancer is the most common cause of cancer-related death worldwide. Early and automatic diagnosis of Solitary Pulmonary Nodules (SPN) in Computer Tomography (CT) chest scans can provide early treatment as well as doctor liberation from…

Image and Video Processing · Electrical Eng. & Systems 2020-03-31 Ioannis D. Apostolopoulos

This work presents an algorithm for determining the parameters of a nonlinear dynamic model of the respiratory system in patients undergoing assisted ventilation. Using the pressure and flow signals measured at the mouth, the model's…

Systems and Control · Electrical Eng. & Systems 2024-03-01 Diego A. Riva , Carolina A. Evangelista , Paul F. Puleston , Luis Corsiglia , Nahuel Dargains

Objective: When patients develop acute respiratory failure, accurately identifying the underlying etiology is essential for determining the best treatment. However, differentiating between common medical diagnoses can be challenging in…

Machine Learning · Computer Science 2022-04-21 Sarah Jabbour , David Fouhey , Ella Kazerooni , Jenna Wiens , Michael W Sjoding

Pulmonary Tuberculosis (PTB) remains a major challenge for global health, especially in areas with poor medical resources, where access to specialized medical knowledge and diagnostic tools is limited. This paper presents an auxiliary…

Image and Video Processing · Electrical Eng. & Systems 2025-02-24 HaoYu Li

Lung cancer, particularly in its advanced stages, remains a leading cause of death globally. Though early detection via low-dose computed tomography (CT) is promising, the identification of high-risk factors crucial for surgical mode…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Xiaotong Fu , Xiangyu Meng , Jing Zhou , Ying Ji

This paper employs Topological Data Analysis (TDA) to detect extreme events (EEs) in the stock market at a continental level. Previous approaches, which analyzed stock indices separately, could not detect EEs for multiple time series in one…

Statistical Finance · Quantitative Finance 2024-05-28 Anish Rai , Buddha Nath Sharma , Salam Rabindrajit Luwang , Md. Nurujjaman , Sushovan Majhi

Electrocardiogram (ECG) is the most crucial monitoring modality to diagnose cardiovascular events. Precise and automatic detection of abnormal ECG patterns is beneficial to both physicians and patients. In the automatic detection of…

Signal Processing · Electrical Eng. & Systems 2020-09-10 Naoki Nonaka , Jun Seita

Topological Data Analysis (TDA) allows us to extract powerful topological and higher-order information on the global shape of a data set or point cloud. Tools like Persistent Homology or the Euler Transform give a single complex description…

Algebraic Topology · Mathematics 2025-11-04 Vincent P. Grande , Michael T. Schaub

Machine learning can be used to analyse physiological data for several purposes. Detection of cerebral ischemia is an achievement that would have high impact on patient care. We attempted to study if collection of continous physiological…

Patients with chronic obstructive pulmonary disease (COPD) have an increased risk of hospitalizations, strongly associated with decreased survival, yet predicting the timing of these events remains challenging and has received limited…

Recently, there has been an explosion in statistical learning literature to represent data using topological principles to capture structure and relationships. We propose a topological data analysis (TDA)-based framework, named Topological…

Machine Learning · Statistics 2025-11-10 Jordan Eckert , Elvan Ceyhan , Henry Schenck

Topological Data Analysis (TDA) combines computational topology and data science to extract and analyze intrinsic topological and geometric structures in data set in a metric space. While the persistent homology (PH), a widely used tool in…

Computational Geometry · Computer Science 2025-04-15 Chuanshen Hu , Yu Wang , Kelin Xia , Ke Ye , Yipeng Zhang

We propose and demonstrate machine learning algorithms to assess the severity of pulmonary edema in chest x-ray images of congestive heart failure patients. Accurate assessment of pulmonary edema in heart failure is critical when making…

Computer Vision and Pattern Recognition · Computer Science 2019-04-11 Ruizhi Liao , Jonathan Rubin , Grace Lam , Seth Berkowitz , Sandeep Dalal , William Wells , Steven Horng , Polina Golland
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