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In this study, we present a highly sensitive Surface Plasmon Resonance (SPR)-based biosensor integrated with a circular-lattice Photonic Crystal Fiber (PCF) for early-stage cancer detection. The proposed sensor leverages the synergy between…

Mycotoxins comprise a frequent type of toxins present in food and feed. The problem of mycotoxin contamination has been recently aggravated due to the increased complexity of the farm-to-fork chains, resulting in negative effects on human…

An ultra-sensitive sensor based on long-period fiber graings (LPFGs) has been fabricated for the detection of methanol and water content in ethanol. Our sensor is very compact in size, highly accurate and easy to fabricate making it very…

Applied Physics · Physics 2018-10-16 Krishnendu Dandapat , Indrajeet Kumar , Saurabh Mani Tripathi

We present a lithium niobate multi-functional platform (LN-MFP) that integrates photoacoustic and thermoelastic spectroscopy with photodetection on a single chip. Utilizing LN's piezoelectric and thermoelastic properties and an optimized…

Optics · Physics 2025-06-02 Haoyang Lin , Wenguo Zhu , Yongchun Zhong , Huihui Lu , Jianhui Yu , Huadan Zheng

In this work, we proposed a high resolution D-shaped photonic crystal fiber (PCF) surface plasmon resonance (SPR) sensor based on gold grating. Gold grating is introduced to modulate the resonance wavelength and enhance the refractive index…

Optics · Physics 2018-08-01 Junjie Lu , Yan Li , Yanhua Han , Yi Liu , Jianmin Gao

We present an innovative method to enhance Long Period Optical Fiber Gratings (LPGs) for refractive index sensing using microsphere-assisted superlens laser nanostructuring. This technique involves self-assembling a silica microsphere…

Optics · Physics 2023-11-13 Yiduo Chen , Liyang Yue , Zengbo Wang

The present work addressed in this thesis introduces, for the first time, the use of tilted fiber Bragg grating (TFBG) sensors for accurate, real-time, and in-situ characterization of CVD and ALD processes for noble metals, but with a…

Chemical Physics · Physics 2017-11-29 David J. Mandia

This paper presents a comprehensive study on a novel multilayer surface plasmon resonance (SPR) biosensor designed for detecting trace-level toxins in liquid samples with exceptional precision and efficiency. Leveraging the Kretschmann…

Systems and Control · Electrical Eng. & Systems 2025-01-31 Suripto Bhuiyan , Michael Geller

Surface plasmon resonance (SPR) sensors built on photonic crystal fibers (PCFs) have recently become a promising category of optical sensing platforms. This is primarily due to their high sensitivity, compact structural design and ability…

Simple and low-cost biosensing solutions are suitable for point-of-care applications aiming to overcome the gap between scientific concepts and technological production. To compete with sensitivity and selectivity of golden standards, such…

Electrical detection of messenger ribonucleic acid (mRNA) is a promising approach to enhancing transcriptomics and disease diagnostics because of its sensitivity, rapidity, and modularity. Reported here is a fast SARS-CoV-2 mRNA biosensor…

Biomolecules · Quantitative Biology 2022-05-12 Nicholas E. Fuhr , Mohamed Azize , David J. Bishop

The achievement of all-fibre functional nano-modules for subcellular label-free measurement has long been pursued due to the limitations of manufacturing techniques. In this paper, a compact all-fibre label-free nano-sensor composed of a…

Optical microcavity enhanced light-matter interaction offers a powerful tool to develop fast and precise sensing techniques, spurring applications in the detection of biochemical targets ranging from cells, nanoparticles, and large…

The selection of a suitable plasmonic material is extremely crucial for achieving high-performance photonic crystal fiber-based surface plasmon resonance (PCF-SPR) sensors. However, most numerical investigations to date are limited to…

Optics · Physics 2023-07-18 Tasmiah Tunazzina , Fairuz Areefin Khan , Anuva Chowdhury

A novel nanostructured electrochemical immunsensor for the determination of progesterone is reported. The approach combines the properties of gold nanoparticles with the use of a graphite-Teflon composite electrode matrix, into which gold…

Materials Science · Physics 2007-08-13 J. -M. Pingarron , P. Yanez-Sedeno , A. Gonzalez-Cortes , V. Carralero

Colorectal liver metastases (CRLM) are a major cause of cancer-related mortality, and reliable detection on CT remains challenging in multi-centre settings. We developed a foundation model-based AI pipeline for patient-level classification…

Limited sensitivity and sensing range are arguably the greatest challenges in microwave sensor design. Recent attempts to improve these properties have relied on metamaterial- (MTM-) inspired open-loop resonators (OLRs) coupled to…

Applied Physics · Physics 2018-10-01 Mohammad Abdolrazzaghi , Mojgan Daneshmand , Ashwin K. Iyer

The present generation of Micro-Pattern Gaseous Detectors (MPGDs) are radiation hard detectors, capable of detecting efficiently particle rates of several MHz/cm$^2$ , while exhibiting good spatial resolution ($\leq$ 50 $\mu$m) and modest…

The microfluidic optomechanical resonator (uFOMR) based on a thin-walled glass capillary supports high Q-factor (>1000) mechanical modes in the presence of liquids. In this Letter, the sensitivity of the uFOMR to the surface change is…

Optics · Physics 2015-09-01 Kyu Hyun Kim , Xudong Fan

Addressing the temperature and strain induced cross-talks simultaneously, we propose an inherently strain and temperature insensitive fiber-optic bio-sensor. The insensitivity has been achieved by properly adjusting the dopants and their…

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