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The dynamics of colloidal particles in potential energy landscapes have mainly been investigated theoretically. In contrast, here we discuss the experimental realization of potential energy landscapes with the help of light fields and the…

Inside cells, cargos such as vesicles and organelles are transported by molecular motors to their correct locations via active motion on cytoskeletal tracks and passive, Brownian diffusion. During the transportation of cargos, motor-cargo…

Soft Condensed Matter · Physics 2018-04-10 Supravat Dey , Kevin Ching , Moumita Das

Boolean networks are a popular modeling framework in computational biology to capture the dynamics of molecular networks, such as gene regulatory networks. It has been observed that many published models of such networks are defined by…

Molecular Networks · Quantitative Biology 2019-12-06 Elijah Paul , Gleb Pogudin , William Qin , Reinhard Laubenbacher

Channels are fundamental building blocks from biophysics to soft robotics, often used to transport or separate solutes. As solute particles inevitably transverse between streamlines along the channel by molecular diffusion, the effective…

Soft Condensed Matter · Physics 2020-02-10 Sophie Marbach , Karen Alim

This paper presents experimental results about transport of dilute suspensions of nano-objects in silicon-glass micrometric and sub-micrometric channels. Two kinds of objects are used: solid, rigid latex beads and spherical capsule-shaped,…

Describing the diffusion of particles through crowded, confined environments with which they can interact is of considerable biological and technological interest. Under conditions where the confinement dimensions become comparable to the…

Soft Condensed Matter · Physics 2009-11-13 Mark L. Henle , Brian DiDonna , Christian D. Santangelo , Ajay Gopinathan

We investigate a driven two-channel system where particles on different lanes mutually obstruct each others motion extending an earlier model by Popkov and Peschel [1]. This obstruction may occur in biological contexts due to steric…

Biological Physics · Physics 2015-03-13 Anna Melbinger , Tobias Reichenbach , Thomas Franosch , Erwin Frey

We investigate the transport of Brownian particles in a two-dimensional potential under the action of a uniform external force. The potential is periodic in one direction and confines the particle to a narrow channel of varying…

Statistical Mechanics · Physics 2016-05-04 Xinli Wang , German Drazer

Many living and physical systems such as cell aggregates, tissues or bacterial colonies behave as unconventional systems of particles that are strongly constrained by volume exclusion and shape interactions. Understanding how these…

Quantitative Methods · Quantitative Biology 2026-05-20 Antoine Diez , Jean Feydy

Particle transport through an open, discrete 1-D channel against a mechanical or chemical bias is analyzed within a master equation approach. The channel, externally driven by time dependent site energies, allows multiple occupation due to…

Statistical Mechanics · Physics 2015-05-18 Mario Einax , Gemma Solomon , Wolfgang Dieterich , Abraham Nitzan

Motivated by experiments in which a polynucleotide is driven through a proteinaceous pore by an electric field, we study the diffusive motion of a polymer threaded through a narrow channel with which it may have strong interactions. We show…

Biological Physics · Physics 2009-10-31 David K. Lubensky , David R. Nelson

In one-dimension, the diffusion of particles along a line is slowed by the addition of energy barriers. The same is true in two-dimensions, provided that the confining channel in which the particles move doesn't change shape. However, if…

Statistical Mechanics · Physics 2022-06-08 Thomas Gray , Claudio Castelnovo , Ee Hou Yong

Nuclear pore complexes are constantly confronted by large fluxes of macromolecules and macromolecular complexes that need to get into and out of the nucleus. Such bi-directional traffic occurring in a narrow channel can easily lead to…

Biological Physics · Physics 2008-07-22 Ruti Kapon , Alon Topchik , David Mukamel , and Ziv Reich

A salient feature of topological phases are surface states and many of the widely studied physical properties are directly tied to their existence. Although less explored, a variety of topological phases can however similarly be…

Mesoscale and Nanoscale Physics · Physics 2021-08-11 Toshikaze Kariyado , Robert-Jan Slager

Gas permeation through nanoscale pores is ubiquitous in nature and plays an important role in a plethora of technologies. Because the pore size is typically smaller than the mean free path of gas molecules, their flow is conventionally…

Mesoscale and Nanoscale Physics · Physics 2018-06-25 A. Keerthi , A. K. Geim , A. Janardanan , A. P. Rooney , A. Esfandiar , S. Hu , S. A. Dar , I. V. Grigorieva , S. J. Haigh , F. C. Wang , B. Radha

We discuss various models of ion transport through cell membrane channels. Recent experimental data shows that sizes of ion channels are compared to those of ions and that only few ions may be simultaneously in any single channel.…

Subcellular Processes · Quantitative Biology 2007-06-06 Jan Gomulkiewicz , Jacek Miekisz , Stanislaw Miekisz

The transport and dispersion of multiple species of charged ions are central to many biological and physical processes, including electrokinetic ion separation. However, most theoretical studies of dispersion in channels have focused on…

Soft Condensed Matter · Physics 2026-05-04 Thakurdas Mahata , Anirban Chatterjee , Ameeya Kumar Nayak

Complex systems often have features that can be modeled by advanced mathematical tools [1]. Of special interests are the features of complex systems that have a network structure as such systems are important for modeling technological and…

Classical Physics · Physics 2019-06-13 Nikolay K. Vitanov , Kaloyan N. Vitanov , Zlatinka I. Dimitrova

It has long been accepted that the multiple-ion single-file transport model is appropriate for many kinds of ion channels. However, most of the purely theoretical works in this field did not capture all of the important features of the…

Biological Physics · Physics 2013-09-02 Kuo Kan Liang

The statistical-mechanical study of the equilibrium properties of fluids, starting from the knowledge of the interparticle interaction potential, is essential to understand the role that microscopic interaction between individual particles…

Soft Condensed Matter · Physics 2025-10-07 Ana M. Montero