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In oncology, treating cancer with a beam of photons is a well established therapeutic technique, developed over 100 years, and today over 50% of cancer patients will undergo traditional X-ray radiotherapy. However, ionizing radiation…

Medical Physics · Physics 2016-02-08 Mersini Makropoulou

We are in a golden age of progress in artificial intelligence (AI). Radiotherapy, due to its technology-intensive nature as well as direct human-machine interactions, is perfectly suited for benefitting from AI to enhance accuracy and…

Medical Physics · Physics 2022-11-21 Hao Peng , Chao Wu , Dan Nguyen , Jan Schuemann , Andrea Mairani , Yuehu Pu , Steve Jiang

Hadrontherapy is a novel technique of cancer radiation therapy which employs beams of charged hadrons, protons and carbon ions in particular. Due to their physical and radiobiological properties, they allow one to obtain a more conformal…

Medical Physics · Physics 2015-05-14 Saverio Braccini

The radiotherapy of malignant diseases has reached much progress during the past decade. Thus, intensity modulated radiation therapy (IMRT) and VMAT (Rapidarc) now belong to the standard modalities of tumor treatment with high energy…

Medical Physics · Physics 2016-11-15 W. Ulmer , A. Carabe-Fernandez

Radiotherapy is one of the main methods in the successful treatment of cancer. The tumor is irradiated with photons or charged particles (e.g. protons), and in the case of massive charged particles, the treatment results in less unnecessary…

Medical Physics · Physics 2019-03-20 Monika Varga-Kofarago

Almost since the time of the discovery of the neutron more than 70 years ago, efforts have been made to understand the effects of neutron radiation on tissue and, eventually, to use neutrons for cancer treatment. In contrast to charged…

Nuclear Experiment · Physics 2010-12-15 S. Pomp

It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with…

Plasma Physics · Physics 2014-05-13 K. W. D. Ledingham , P. R. Bolton , N. Shikazono , C-M. Ma

The field of particle therapy is quickly growing and yet it's more widespread adoption is limited by size, cost and adaptation to the more conformal treatment techniques. In order to realize the benefits of this modality the equipment used…

Medical Physics · Physics 2018-04-25 Jay Flanz

Recent developments for the delivery of proton and ion beam therapy have been significant, and a number of technological solutions now exist for the creation and utilisation of these particles for the treatment of cancer. In this paper we…

Accelerator Physics · Physics 2015-06-17 Hywel Owen , David Holder , Jose Alonso , Ranald MacKay

With the continued evolution of modern radiation therapy towards high precision delivery of high therapeutic doses to the tumour while optimally sparing surrounding healthy tissue, imaging becomes a crucial component to identify the…

Medical Physics · Physics 2018-04-24 Katia Parodi

Radiation therapy is an effective and widely accepted form of treatment for many types of cancer that requires extensive computerized planning. Unfortunately, current treatment planning systems have limited or no visual aid that combines…

Graphics · Computer Science 2018-11-30 Felix G. Hamza-Lup , Ivan Sopin , Omar Zeidan

Boron Neutron Capture Therapy (BNCT) is a neutron radiotherapy used to treat tumours cells previously doping with Boron-10. This therapy requires an epithermal neutron beam for the treatment of deep tumours and a thermal beam for shallow…

Instrumentation and Detectors · Physics 2021-06-02 M. Macías , B. Fernández , J. Praena

Purpose: Proton therapy provides superior dose conformity compared to photon therapy, but its treatment planning is challenged by sensitivity to anatomical changes, setup/range uncertainties, and computational complexity. This review…

Neutron stars have long been regarded as extra-terrestrial laboratories from which we can learn about extreme energy density matter at low temperatures. In this article, I highlight some of the recent advances made in astrophysical…

Solar and Stellar Astrophysics · Physics 2023-07-19 Madappa Prakash

Proton therapy is a cancer treatment technique currently in growth worldwide. It offers advantages with respect to conventional X-ray and $\gamma$-ray radiotherapy, in particular, a better control of the dose deposition allowing to reach a…

In the past decades mathematical optimization has found its way into radiation therapy and has made profound practice changing impact. Today, virtually all advanced treatment delivery methods, such as IMRT, VMAT, tomotherapy, LDR/HDR…

Medical Physics · Physics 2018-10-31 Bram L. Gorissen , Jan Unkelbach , Thomas R. Bortfeld

To improve the quality of cancer treatment with protons, a translation of X-ray Computed Tomography (CT) images into a map of the proton stopping powers needs to be more accurate. Proton stopping powers determined from CT images have…

Stereotactic body radiation therapy (SBRT) refers to focusing high-energy rays in three-dimensional space on the tumor lesion area, reducing the dose received by surrounding normal tissues, which can effectively improve the local control…

Medical Physics · Physics 2024-02-27 Yanqi Zong , Zhengrong Cui , Luqi Lin , Sihao Wang , Yizhi Chen

It has long been known that radiation biology plays an important role and it is necessary for radiotherapy treatments. The radiation effects on normal and malignant tissues after exposure range from a femtosecond to months and years…

Medical Physics · Physics 2017-04-24 Cyril Voyant , Daniel Julian

Laser acceleration promises innovation in particle beam therapy of cancer where an ultra-compact accelerator system for cancer beam therapy can become affordable to a broad range of patients. This is not feasible without the introduction of…

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