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The gradual accumulation of damage and dysregulation during the aging of living organisms can be quantified. Even so, the aging process is complex and has multiple interacting physiological scales -- from the molecular to cellular to whole…

Quantitative Methods · Quantitative Biology 2021-05-06 Spencer Farrell , Garrett Stubbings , Kenneth Rockwood , Arnold Mitnitski , Andrew Rutenberg

The nature of software re-engineering is to improve or transform existing software so it can be understood, controlled and reused as new software. Needs, the necessity of re-engineering software has greatly increased. The system software…

Software Engineering · Computer Science 2011-12-20 Phuc V. Nguyen

Software Engineering is a constantly evolving subject area that faces new challenges every day as it tries to automate newer business processes. One of the key challenges to the success of a software solution is attaining sustainability.…

Software Engineering · Computer Science 2019-10-15 Asif Imran , Tevfik Kosar

This paper presents the results of a research study related to software system failures, with the goal of understanding how we might better evolve, maintain and support software systems in production. We have qualitatively analyzed thirty…

Software Engineering · Computer Science 2020-08-26 Jonathan Sillito , Esdras Kutomi

Sustainability is an increasingly-studied topic in software engineering in general, and in software architecture in particular. There are already a number of secondary studies addressing sustainability in software engineering, but no such…

Software Engineering · Computer Science 2022-04-26 Vasilios Andrikopoulos , Rares-Dorian Boza , Carlos Perales , Patricia Lago

Many theories have been proposed to answer two questions on aging: "Why do we age?" and "How do we age?" Among them, evolutionary theories are proposed to interpret the evolutionary advantage of aging, and "saving resources for group…

Other Quantitative Biology · Quantitative Biology 2017-01-04 Jicun Wang-Michelitsch , Thomas Michelitsch

Software developers attempt to reproduce software bugs to understand their erroneous behaviours and to fix them. Unfortunately, they often fail to reproduce (or fix) them, which leads to faulty, unreliable software systems. However, to…

Software Engineering · Computer Science 2021-08-12 Mohammad Masudur Rahman , Foutse Khomh , Marco Castelluccio

Software-intensive systems constantly evolve. To prevent software changes from unintentionally introducing costly system defects, it is important to understand their impact to reduce risk. However, it is in practice nearly impossible to…

Software Engineering · Computer Science 2022-05-18 Dennis Hendriks , Arjan van der Meer , Wytse Oortwijn

It is now increasingly realized that the underlying mechanism which governs aging (ageing) is a complex interplay of genetic regulation and damage-accumulation. "Aging as a result of accumulation of 'faults' on cellular and molecular…

Tissues and Organs · Quantitative Biology 2011-03-31 Jicun Wang , Thomas Michelitsch , Arne Wunderlin , Ravi Mahadeva

The traditional methods of the biology, based on illustrative descriptions and linear logic explanations, are discussed. This work aims to improve this approach by introducing alternative tools to describe and represent complex biological…

Computational Engineering, Finance, and Science · Computer Science 2012-01-24 Alvaro Juan Ojeda Garcia

What is aging? Mechanistic answers to this question remain elusive despite decades of research. Here, we propose a mathematical model of cellular aging based on a model gene interaction network. Our network model is made of only non-aging…

Molecular Networks · Quantitative Biology 2023-09-12 Hong Qin

This chapter investigates the evolutionary ecology of software, focusing on the symbiotic relationship between software and innovation. An interplay between constraints, tinkering, and frequency-dependent selection drives the complex…

Software Engineering · Computer Science 2025-12-03 Sergi Valverde , Blai Vidiella , Salva Duran-Nebreda

Distributed systems in general and cloud systems in particular, are susceptible to failures that can lead to substantial economic and data losses, security breaches, and even potential threats to human safety. Software ageing is an example…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-04-26 Yevhen Yazvinskyi , Jasmin Bogatinovski , Jorge Cardoso , Odej Kao

The software is changing rapidly with the invention of advanced technologies and methodologies. The ability to rapidly and successfully upgrade software in response to changing business requirements is more vital than ever. For the…

Software Engineering · Computer Science 2022-09-22 Gokul Yenduri , Thippa Reddy Gadekallu

Neutral landscapes and mutational robustness are believed to be important enablers of evolvability in biology. We apply these concepts to software, defining mutational robustness to be the fraction of random mutations that leave a program's…

Software Engineering · Computer Science 2013-06-28 Eric Schulte , Zachary P. Fry , Ethan Fast , Westley Weimer , Stephanie Forrest

The continuous software engineering paradigm is gaining popularity in modern development practices, where the interleaving of design and runtime activities is induced by the continuous evolution of software systems. In this context,…

Software Engineering · Computer Science 2024-01-31 Romina Eramo , Michele Tucci , Daniele Di Pompeo , Vittorio Cortellessa , Antinisca Di Marco , Davide Taibi

Generative AI enables rapid ``vibe coding," where natural language prompts yield working software systems. While this lowers barriers to software creation, it also collapses the boundary between prototypes and engineered software, leading…

Software Engineering · Computer Science 2025-11-12 Jürgen Cito , Dominik Bork

Software systems endure many noteworthy changes throughout their life-cycle in order to follow the evolution of the problem domains. Generally, the software system architecture cannot follow the rapid evolution of a problem domain which…

Software Engineering · Computer Science 2011-11-30 Humaira Farid , Farooque Azam , M. Aqeel Iqbal

The capacity to adapt can greatly influence the success of systems that need to compensate for damaged parts, learn how to achieve robust performance in new environments, or exploit novel opportunities that originate from new technological…

Adaptation and Self-Organizing Systems · Physics 2011-12-15 James Whitacre , Axel Bender

Software reliability analysis is performed at various stages during the process of engineering software as an attempt to evaluate if the software reliability requirements have been (or might be) met. In this report, I present a summary of…

Software Engineering · Computer Science 2013-04-17 Ganesh J. Pai