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We consider the problem of assessing the importance of multiple variables or factors from a dataset when side information is available. In principle, using side information can allow the statistician to pay attention to variables with a…

Methodology · Statistics 2020-01-23 Zhimei Ren , Emmanuel Candès

Often in language and other areas of cognition, whether two components of an object are identical or not determines if it is well formed. We call such constraints identity effects. When developing a system to learn well-formedness from…

Machine Learning · Computer Science 2022-03-03 S. Brugiapaglia , M. Liu , P. Tupper

Learning tasks such as those involving genomic data often poses a serious challenge: the number of input features can be orders of magnitude larger than the number of training examples, making it difficult to avoid overfitting, even when…

The widespread adoption of deep-learning models in data-driven applications has drawn attention to the potential risks associated with biased datasets and models. Neglected or hidden biases within datasets and models can lead to unexpected…

Machine Learning · Computer Science 2026-01-27 Md Sahidullah , Hye-jin Shim , Rosa Gonzalez Hautamäki , Tomi H. Kinnunen

Many biological data analysis processes like Cytometry or Next Generation Sequencing (NGS) produce massive amounts of data which needs to be processed in batches for down-stream analysis. Such datasets are prone to technical variations due…

Machine Learning · Computer Science 2019-06-24 Uddeshya Upadhyay , Arjun Jain

As synthetic imagery is used more frequently in training deep models, it is important to understand how different synthesis techniques impact the performance of such models. In this work, we perform a thorough evaluation of the…

Computer Vision and Pattern Recognition · Computer Science 2019-09-05 Kristofer Schlachter , Connor DeFanti , Sebastian Herscher , Ken Perlin , Jonathan Tompson

Nigam et al. reported a genetic algorithm (GA) utilizing the SELFIES representation and also propose an adaptive, neural network-based penalty that is supposed to improve the diversity of the generated molecules. The main claims of the…

Machine Learning · Computer Science 2021-02-11 Kevin Maik Jablonka , Fergus Mcilwaine , Susana Garcia , Berend Smit , Brian Yoo

Multi-task learning has shown to significantly enhance the performance of multiple related learning tasks in a variety of situations. We present the fused logistic regression, a sparse multi-task learning approach for binary classification.…

Machine Learning · Statistics 2013-12-31 Venelin Mitov , Manfred Claassen

Generating a novel and optimized molecule with desired chemical properties is an essential part of the drug discovery process. Failure to meet one of the required properties can frequently lead to failure in a clinical test which is costly.…

Machine Learning · Computer Science 2020-10-28 Bonggun Shin , Sungsoo Park , JinYeong Bak , Joyce C. Ho

Drugs are frequently prescribed to patients with the aim of improving each patient's medical state, but an unfortunate consequence of most prescription drugs is the occurrence of undesirable side effects. Side effects that occur in more…

Machine Learning · Computer Science 2016-11-15 Jenna Reps , Jonathan M. Garibaldi , Uwe Aickelin , Daniele Soria , Jack E. Gibson , Richard B. Hubbard

Semi-supervised algorithms aim to learn prediction functions from a small set of labeled observations and a large set of unlabeled observations. Because this framework is relevant in many applications, they have received a lot of interest…

Machine Learning · Computer Science 2025-02-17 Massih-Reza Amini , Vasilii Feofanov , Loic Pauletto , Lies Hadjadj , Emilie Devijver , Yury Maximov

In recent years, with the development of microarray technique, discovery of useful knowledge from microarray data has become very important. Biclustering is a very useful data mining technique for discovering genes which have similar…

Computational Engineering, Finance, and Science · Computer Science 2009-09-09 Mohsen lashkargir , S. Amirhassan Monadjemi , Ahmad Baraani Dastjerdi

Gender classification algorithms have important applications in many domains today such as demographic research, law enforcement, as well as human-computer interaction. Recent research showed that algorithms trained on biased benchmark…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Wenying Wu , Pavlos Protopapas , Zheng Yang , Panagiotis Michalatos

The Machine Learning has various learning algorithms that are better in some or the other aspect when compared with each other but a common error that all algorithms will suffer from is training data with very high dimensional feature set.…

Machine Learning · Computer Science 2022-02-21 Sruthi Nair , Abhishek Gupta , Raunak Joshi , Vidya Chitre

Generative Adversarial Networks (GANs) can successfully approximate a probability distribution and produce realistic samples. However, open questions such as sufficient convergence conditions and mode collapse still persist. In this paper,…

Machine Learning · Computer Science 2019-03-13 Thang Doan , Joao Monteiro , Isabela Albuquerque , Bogdan Mazoure , Audrey Durand , Joelle Pineau , R Devon Hjelm

The paper presents the investigation and implementation of the relationship between diversity and the performance of multiple classifiers on classification accuracy. The study is critical as to build classifiers that are strong and can…

Artificial Intelligence · Computer Science 2008-10-22 R. Musehane , F. Netshiongolwe , F. V. Nelwamondo , L. Masisi , T. Marwala

The identification of predictive biomarkers from a large scale of covariates for subgroup analysis has attracted fundamental attention in medical research. In this article, we propose a generalized penalized regression method with a novel…

Methodology · Statistics 2019-04-29 Chong Ma , Wenxuan Deng , Shuangge Ma , Ray Liu , Kevin Galinsky

This paper considers an anomaly detection problem in which a detection algorithm assigns anomaly scores to multi-dimensional data points, such as cellular networks' Key Performance Indicators (KPIs). We propose an optimization framework to…

Information Theory · Computer Science 2023-09-01 Ali Maatouk , Fadhel Ayed , Wenjie Li , Yu Wang , Hong Zhu , Jiantao Ye

Interactions between genes and environmental factors may play a key role in the etiology of many common disorders. Several regularized generalized linear models (GLMs) have been proposed for hierarchical selection of gene by environment…

Methodology · Statistics 2023-12-22 Julien St-Pierre , Karim Oualkacha , Julien St-Pierre

This paper describes an innovative way to optimize a multivariate classifier, in particular a Support Vector Machine algorithm, on a problem characterized by a biased training sample. This is possible thanks to the feedback of a…

High Energy Physics - Experiment · Physics 2014-07-02 Federico Sforza , Vittorio Lippi