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Genome-wide association studies (GWAS) have identified hundreds of loci at very stringent levels of statistical significance across many different human traits. However, it is now clear that very large samples (n~10^4-10^5) are needed to…

Genomics · Quantitative Biology 2013-08-20 Inti Pedroso

The paper by Leiva et al. (2010) introduced a skewed version of the sinh-normal distribution, discussed some of its properties and characterized an extension of the Birnbaum-Saunders distribution associated with this distribution. In this…

Methodology · Statistics 2011-11-22 Artur J. Lemonte

This paper introduces constrained mixtures for continuous distributions, characterized by a mixture of distributions where each distribution has a shape similar to the base distribution and disjoint domains. This new concept is used to…

Machine Learning · Statistics 2015-03-29 Conrado S. Miranda , Fernando J. Von Zuben

In the context of survival analysis, Marshall and Olkin (1997) introduced families of distributions by adding a scalar parameter to a given survival function, parameterized or not. In that paper, we generalize their approach. We show how it…

Methodology · Statistics 2011-07-21 Damien Bousquet , Jean-Pierre Daurès , Jean-Michel Marin

In this paper a new distribution is proposed. This new model provides more flexibility to modeling data with upside-down bathtub hazard rate function. A significant account of mathematical properties of the new distribution is presented.…

Statistics Theory · Mathematics 2017-11-28 Pedro L. Ramos , Francisco Louzada , Taciana K. O. Shimizu , Aline O. Luiz

We offer a new perspective on risk aggregation with FGM copulas. Along the way, we discover new results and revisit existing ones, providing simpler formulas than one can find in the existing literature. This paper builds on two novel…

Statistics Theory · Mathematics 2022-08-01 Christopher Blier-Wong , Hélène Cossette , Etienne Marceau

The recent paper by I. Weissman, "Sum of squares of uniform random variables",[Statist. Probab. Lett. 129 (2017), 147-154] is compared to earlier work of B. Tibken and D. Constales relating to the area of the intersection of a centred ball…

Probability · Mathematics 2022-10-17 Peter J. Forrester

Finite mixture of skew distributions have emerged as an effective tool in modelling heterogeneous data with asymmetric features. With various proposals appearing rapidly in the recent years, which are similar but not identical, the…

Methodology · Statistics 2013-05-29 Sharon X. Lee , Geoffrey J. McLachlan

The distribution of the sum of dependent risks is a crucial aspect in actuarial sciences, risk management and in many branches of applied probability. In this paper, we obtain analytic expressions for the probability density function (pdf)…

Methodology · Statistics 2017-05-02 José María Sarabia , Emilio Gómez-Déniz , Faustino Prieto , Vanesa Jordá

In this paper, a new class of distributions, called Odds xgamma-G (OXG-G) family of distribu- tions is proposed for modeling lifetime data. A comprehensive account of the mathematical proper- ties of the new class including estimation issue…

Statistics Theory · Mathematics 2018-05-11 Sudhansu S. Maiti , Sukanta Pramanik

The family of multivariate skew-normal distributions has many interesting properties. It is shown here that these hold for a general class of skew-elliptical distributions. For this class, several stochastic representations are established…

Statistics Theory · Mathematics 2023-09-18 Chuancun Yin , Narayanaswamy Balakrishnan

A generalization of the generalized inverse Weibull distribution so-called transmuted generalized inverse Weibull dis- tribution is proposed and studied. We will use the quadratic rank transmutation map (QRTM) in order to generate a…

Methodology · Statistics 2013-09-16 Faton Merovci , Ibrahim Elbatal , Alaa Ahmed

Discussion paper on "Fast Approximate Inference for Arbitrarily Large Semiparametric Regression Models via Message Passing" by Wand [arXiv:1602.07412].

Computation · Statistics 2016-09-20 Dustin Tran , David M. Blei

Rejoinder to ``Analysis of variance--why it is more important than ever'' by A. Gelman [math.ST/0504499]

Statistics Theory · Mathematics 2007-06-13 Andrew Gelman

Random-effects models are central to meta-analysis, yet the between-study variance is often underestimated when the number of studies is small. In such settings, confidence intervals become unduly narrow and fail to attain the nominal…

Methodology · Statistics 2025-11-18 Keisuke Hanada , Tomoyuki Sugimoto

Genetic Gaussian network of multiple phenotypes constructed through the genetic correlation matrix is informative for understanding their biological dependencies. However, its interpretation may be challenging because the estimated genetic…

Methodology · Statistics 2024-12-31 Yihe Yang , Noah Lorincz-Comi , Xiaofeng Zhu

Consider bivariate observations $(X_1,Y_1), \ldots, (X_n,Y_n) \in \mathbb{R}\times \mathbb{R}$ with unknown conditional distributions $Q_x$ of $Y$, given that $X = x$. The goal is to estimate these distributions under the sole assumption…

Statistics Theory · Mathematics 2025-01-31 Alexandre Mösching , Lutz Duembgen

This article aims to introduced a new distribution named as extended xgamma (EXg) distribution. This generalization is derived from xgamma distribution (Xg), a special finite mixture of exponential and gamma distributions [see, Sen et al.…

Statistics Theory · Mathematics 2019-09-04 Mahendra Saha , Abhimanyu Singh Yadav , Arvind Pandey , Shivanshi Shukla , Sudhansu S Maiti

Mendelian randomization (MR) is an epidemiological method that can be used to strengthen causal inference regarding the relationship between a modifiable environmental exposure and a medically relevant trait and to estimate the magnitude of…

Quantitative Methods · Quantitative Biology 2023-08-30 David M Evans , George Davey Smith , Gunn-Helen Moen

In randomized clinical trials, adjusting for baseline covariates can improve credibility and efficiency for demonstrating and quantifying treatment effects. This article studies the augmented inverse propensity weighted (AIPW) estimator,…

Methodology · Statistics 2024-03-27 Marlena S. Bannick , Jun Shao , Jingyi Liu , Yu Du , Yanyao Yi , Ting Ye
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