English
Related papers

Related papers: Signalling Paediatric Side Effects using an Ensemb…

200 papers

Comparative binary outcome data are of fundamental interest in statistics and are often pooled in meta-analyses. Here we examine the simplest case where for each study there are two patient groups and a binary event of interest, giving rise…

Methodology · Statistics 2018-06-12 Rose Baker , Dan Jackson

Models of physical systems are used to explain and predict experimental results and observations. When students encounter discrepancies between the actual and expected behavior of a system, they revise their models to include the newly…

Physics Education · Physics 2022-07-06 Laura Ríos , Benjamin Pollard , Dimitri R. Dounas-Frazer , H. J. Lewandowski

No man is an island, as individuals interact and influence one another daily in our society. When social influence takes place in experiments on a population of interconnected individuals, the treatment on a unit may affect the outcomes of…

Methodology · Statistics 2017-08-30 Edward K. Kao

In the context of individual-level causal inference, we study the problem of predicting whether someone will respond or not to a treatment based on their features and past examples of features, treatment indicator (e.g., drug/no drug), and…

Machine Learning · Statistics 2019-06-04 Nathan Kallus

In the past two decades, psychological science has experienced an unprecedented replicability crisis which uncovered several issues. Among others, statistical inference is too often viewed as an isolated procedure limited to the analysis of…

The test-negative design has become popular for evaluating the effectiveness of post-licensure vaccines using observational data. In addition to its logistical convenience on data collection, the design is also believed to control for the…

Methodology · Statistics 2026-05-15 Soumyabrata Kundu , Peng Ding , Jingshu Wang , Xinran Li

Post--marketing pharmacovigilance is essential for identifying adverse drug reactions (ADRs) that elude detection during pre--marketing clinical trials. This study explores a novel approach that integrates an adverse event (AE) ontology…

Treatment non-compliance, where individuals deviate from their assigned experimental conditions, frequently complicates the estimation of causal effects. To address this, we introduce a novel learning framework based on a mixture of experts…

Methodology · Statistics 2025-06-25 François Grolleau , Céline Béji , Raphaël Porcher , François Petit

This paper studies identification and estimation of average causal effects, such as average marginal or treatment effects, in fixed effects logit models with short panels. Relating the identified set of these effects to an extremal moment…

Econometrics · Economics 2024-12-20 Laurent Davezies , Xavier D'Haultfœuille , Louise Laage

Adverse drug reactions (ADRs) are unwanted or harmful effects experienced after the administration of a certain drug or a combination of drugs, presenting a challenge for drug development and drug administration. In this paper, we present a…

Computation and Language · Computer Science 2019-05-29 Maksim Belousov , Nikola Milosevic , William Dixon , Goran Nenadic

The case$^2$ study, also referred to as the case-case study design, is a valuable approach for conducting inference for treatment effects. Unlike traditional case-control studies, the case$^2$ design compares treatment in two types of cases…

Methodology · Statistics 2025-03-03 Kan Chen , Ting Ye , Dylan S. Small

There is increasing interest in combining information from experimental studies, including randomized and single-group trials, with information from external experimental or observational data sources. Such efforts are usually motivated by…

Methodology · Statistics 2026-04-23 Lawson Ung , Guanbo Wang , Sebastien Haneuse , Miguel A. Hernán , Issa J. Dahabreh

We investigate the use of sequence analysis for behavior modeling, emphasizing that sequential context often outweighs the value of aggregate features in understanding human behavior. We discuss framing common problems in fields like…

Machine Learning · Computer Science 2024-11-06 Maxime Kawawa-Beaudan , Srijan Sood , Soham Palande , Ganapathy Mani , Tucker Balch , Manuela Veloso

In clinical treatment, identifying potential adverse reactions of drugs can help assist doctors in making medication decisions. In response to the problems in previous studies that features are high-dimensional and sparse, independent…

Quantitative Methods · Quantitative Biology 2024-07-30 Yufeng Li , Wenchao Zhao , Bo Dang , Xu Yan , Weimin Wang , Min Gao , Mingxuan Xiao

Constraint-based learning reduces the burden of collecting labels by having users specify general properties of structured outputs, such as constraints imposed by physical laws. We propose a novel framework for simultaneously learning these…

Machine Learning · Computer Science 2018-06-01 Hongyu Ren , Russell Stewart , Jiaming Song , Volodymyr Kuleshov , Stefano Ermon

Incipient anomalies present milder symptoms compared to severe ones, and are more difficult to detect and diagnose due to their close resemblance to normal operating conditions. The lack of incipient anomaly examples in the training data…

Machine Learning · Computer Science 2020-08-21 Baihong Jin , Yingshui Tan , Albert Liu , Xiangyu Yue , Yuxin Chen , Alberto Sangiovanni Vincentelli

Partial multi-label learning and complementary multi-label learning are two popular weakly supervised multi-label classification paradigms that aim to alleviate the high annotation costs of collecting precisely annotated multi-label data.…

Machine Learning · Computer Science 2026-02-26 Wei Wang , Tianhao Ma , Ming-Kun Xie , Gang Niu , Masashi Sugiyama

Estimating varying treatment effects in randomized trials with noncompliance is inherently challenging since variation comes from two separate sources: variation in the impact itself and variation in the compliance rate. In this setting,…

Applications · Statistics 2024-08-28 Jared D. Fisher , David W. Puelz , Sameer K. Deshpande

Exposure mappings are widely used to model potential outcomes in the presence of interference, where each unit's outcome may depend not only on its own treatment, but also on the treatment of other units as well. However, in practice these…

Methodology · Statistics 2018-07-02 David Choi

Weakly supervised data are widespread and have attracted much attention. However, since label quality is often difficult to guarantee, sometimes the use of weakly supervised data will lead to unsatisfactory performance, i.e., performance…

Machine Learning · Computer Science 2019-04-23 Lan-Zhe Guo , Yu-Feng Li , Ming Li , Jin-Feng Yi , Bo-Wen Zhou , Zhi-Hua Zhou