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Objective: Mining the data contained within Electronic Health Records (EHRs) can potentially generate a greater understanding of medication effects in the real world, complementing what we know from Randomised control trials (RCTs). We…

During natural disasters, aircraft and satellites are used to survey the impacted regions. Usually human experts are needed to manually label the degrees of the building damage so that proper humanitarian assistance and disaster response…

Machine Learning · Computer Science 2025-08-05 Jie Wei , Zhigang Zhu , Erik Blasch , Bilal Abdulrahman , Billy Davila , Shuoxin Liu , Jed Magracia , Ling Fang

Synthetic digital twins based on medical data accelerate the acquisition, labelling and decision making procedure in digital healthcare. A core part of digital healthcare twins is model-based data synthesis, which permits the generation of…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Xiaodan Xing , Javier Del Ser , Yinzhe Wu , Yang Li , Jun Xia , Lei Xu , David Firmin , Peter Gatehouse , Guang Yang

We consider the problem of estimating the average treatment effect (ATE) in a semi-supervised learning setting, where a very small proportion of the entire set of observations are labeled with the true outcome but features predictive of the…

Methodology · Statistics 2020-10-27 David Cheng , Ashwin Ananthakrishnan , Tianxi Cai

Healthcare data are inherently multimodal, including electronic health records (EHR), medical images, and multi-omics data. Combining these multimodal data sources contributes to a better understanding of human health and provides optimal…

Machine Learning · Computer Science 2022-10-28 Farida Mohsen , Hazrat Ali , Nady El Hajj , Zubair Shah

The work for predicting drug and target affinity(DTA) is crucial for drug development and repurposing. In this work, we propose a novel method called GDGRU-DTA to predict the binding affinity between drugs and targets, which is based on…

Quantitative Methods · Quantitative Biology 2022-04-27 Lyu Zhijian , Jiang Shaohua , Liang Yigao , Gao Min

Monitoring the health status of patients in the Intensive Care Unit (ICU) is a critical aspect of providing superior care and treatment. The availability of large-scale electronic health records (EHR) provides machine learning models with…

Artificial Intelligence · Computer Science 2023-05-05 Jun Wu , Xuesong Ye , Chengjie Mou , Weinan Dai

Alzheimer's disease (AD) is an age-specific neurodegenerative disease that compromises cognitive functioning and impacts the quality of life of an individual. Pathologically, AD is characterised by abnormal accumulation of beta-amyloid…

Subcellular Processes · Quantitative Biology 2020-05-29 Alok Joshi , Da-Hui Wang , Steven Watterson , Paula L. McClean , Chandan K. Behera , Trevor Sharp , KongFatt Wong-Lin

Background: Electronic health records (EHRs) enable machine learning for diagnosis, prognosis, and clinical decision support. However, EHR standards vary by country and hospital, making records often incompatible. This limits large-scale…

Information Retrieval · Computer Science 2026-03-27 Jiawei Zhao , Md Shamim Ahmed , Nicolai Dinh Khang Truong , Verena Schuster , Rudolf Mayer , Richard Röttger

Improving the precision of heart diseases detection has been investigated by many researchers in the literature. Such improvement induced by the overwhelming health care expenditures and erroneous diagnosis. As a result, various…

Computers and Society · Computer Science 2018-03-29 Israa Ahmed Zriqat , Ahmad Mousa Altamimi , Mohammad Azzeh

Polypharmacy, most often defined as the simultaneous consumption of five or more drugs at once, is a prevalent phenomenon in the older population. Some of these polypharmacies, deemed inappropriate, may be associated with adverse health…

Machine Learning · Computer Science 2023-04-06 Alexandre Larouche , Audrey Durand , Richard Khoury , Caroline Sirois

The average treatment effect (ATE) is popularly used to assess the treatment effect. However, the ATE implicitly assumes a homogenous treatment effect even amongst individuals with different characteristics. In this paper, we mainly focus…

Methodology · Statistics 2016-03-10 Yunjian Yin , Lan Liu , Zhi Geng

Drugs are frequently prescribed to patients with the aim of improving each patient's medical state, but an unfortunate consequence of most prescription drugs is the occurrence of undesirable side effects. Side effects that occur in more…

Machine Learning · Computer Science 2016-11-15 Jenna Reps , Jonathan M. Garibaldi , Uwe Aickelin , Daniele Soria , Jack E. Gibson , Richard B. Hubbard

Drug Side-Effects (DSEs) have a high impact on public health, care system costs, and drug discovery processes. Predicting the probability of side-effects, before their occurrence, is fundamental to reduce this impact, in particular on drug…

Quantitative Methods · Quantitative Biology 2022-02-17 Pietro Bongini , Franco Scarselli , Monica Bianchini , Giovanna Maria Dimitri , Niccolò Pancino , Pietro Liò

Heart disease is the leading cause of death, and experts estimate that approximately half of all heart attacks and strokes occur in people who have not been flagged as "at risk." Thus, there is an urgent need to improve the accuracy of…

Machine Learning · Computer Science 2018-08-23 Nathalie-Sofia Tomov , Stanimire Tomov

Identification of drug-target interactions is an indispensable part of drug discovery. While conventional shallow machine learning and recent deep learning methods based on chemogenomic properties of drugs and target proteins have pushed…

Quantitative Methods · Quantitative Biology 2024-04-05 Yuanyuan Zhang , Yingdong Wang , Chaoyong Wu , Lingmin Zhana , Aoyi Wang , Caiping Cheng , Jinzhong Zhao , Wuxia Zhang , Jianxin Chen , Peng Li

This paper presents HURRA, a system that aims to reduce the time spent by human operators in the process of network troubleshooting. To do so, it comprises two modules that are plugged after any anomaly detection algorithm: (i) a first…

Artificial Intelligence · Computer Science 2021-07-26 Jose M. Navarro , Dario Rossi

Physics-informed neural networks (PINNs) are neural networks that embed the laws of dynamical systems modeled by differential equations into their loss function as constraints. In this work, we present a PINN framework applied to oncology.…

Machine Learning · Computer Science 2025-10-16 Kayode Olumoyin , Katarzyna Rejniak

Click-Through Rate (CTR) prediction is one of the main tasks of the recommendation system, which is conducted by a user for different items to give the recommendation results. Cross-domain CTR prediction models have been proposed to…

Information Retrieval · Computer Science 2023-05-23 Menglin Kong , Muzhou Hou , Shaojie Zhao , Feng Liu , Ri Su , Yinghao Chen

Social media is an useful platform to share health-related information due to its vast reach. This makes it a good candidate for public-health monitoring tasks, specifically for pharmacovigilance. We study the problem of extraction of…

Information Retrieval · Computer Science 2017-09-07 Shashank Gupta , Sachin Pawar , Nitin Ramrakhiyani , Girish Palshikar , Vasudeva Varma