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Adverse Drug Reactions (ADRs) from psychiatric medications are the leading cause of hospitalizations among mental health patients. With healthcare systems and online communities facing limitations in resolving ADR-related issues, Large…

Deep neural networks are increasingly being used to detect and diagnose medical conditions using medical imaging. Despite their utility, these models are highly vulnerable to adversarial attacks and distribution shifts, which can affect…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Josué Martínez-Martínez , Olivia Brown , Mostafa Karami , Sheida Nabavi

The large amount of time clinicians spend sifting through patient notes and documenting in electronic health records (EHRs) is a leading cause of clinician burnout. By proactively and dynamically retrieving relevant notes during the…

Information Retrieval · Computer Science 2023-08-17 Sharon Jiang , Shannon Shen , Monica Agrawal , Barbara Lam , Nicholas Kurtzman , Steven Horng , David Karger , David Sontag

Traditional drug discovery processes are both time-consuming and require extensive professional expertise. With the accumulation of drug-target interaction (DTI) data from experimental studies, leveraging modern machine-learning techniques…

Quantitative Methods · Quantitative Biology 2024-12-12 Shuqi Li , Shufang Xie , Hongda Sun , Yuhan Chen , Tao Qin , Tianjun Ke , Rui Yan

Early recognition of clinical deterioration is one of the main steps for reducing inpatient morbidity and mortality. The challenging task of clinical deterioration identification in hospitals lies in the intense daily routines of healthcare…

In recent years, the development of Artificial Intelligence (AI) has offered the possibility to tackle many interdisciplinary problems, and the field of chemistry is not an exception. Drug analysis is crucial in drug discovery, playing an…

Biomolecules · Quantitative Biology 2023-11-17 Huynh Quoc Anh Bui , Trong Hop Do , Thanh Binh Nguyen

Objective: Patient notes in electronic health records (EHRs) may contain critical information for medical investigations. However, the vast majority of medical investigators can only access de-identified notes, in order to protect the…

Computation and Language · Computer Science 2016-06-14 Franck Dernoncourt , Ji Young Lee , Ozlem Uzuner , Peter Szolovits

Many diagnostic errors occur because clinicians cannot easily access relevant information in patient Electronic Health Records (EHRs). In this work we propose a method to use LLMs to identify pieces of evidence in patient EHR data that…

We present a graphical, knowledge-based method for reviewing treatment-emergent adverse events (AEs) in clinical trials. The approach enhances MedDRA by adding a hidden medical knowledge layer (Safeterm) that captures semantic relationships…

Computation and Language · Computer Science 2025-11-25 Francois Vandenhende , Anna Georgiou , Michalis Georgiou , Theodoros Psaras , Ellie Karekla , Elena Hadjicosta

In recent years, the focus is on improving the diagnosis of diabetic retinopathy (DR) using machine learning and deep learning technologies. Researchers have explored various approaches, including the use of high-definition medical imaging,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Saideep Kilaru , Kothamasu Jayachandra , Tanishka Yagneshwar , Suchi Kumari

The growing availability of observational databases like electronic health records (EHR) provides unprecedented opportunities for secondary use of such data in biomedical research. However, these data can be error-prone and need to be…

Methodology · Statistics 2024-05-28 Sarah C. Lotspeich , Gustavo G. C. Amorim , Pamela A. Shaw , Ran Tao , Bryan E. Shepherd

The surging availability of electronic medical records (EHR) leads to increased research interests in medical predictive modeling. Recently many deep learning based predicted models are also developed for EHR data and demonstrated…

Machine Learning · Computer Science 2018-02-15 Mengying Sun , Fengyi Tang , Jinfeng Yi , Fei Wang , Jiayu Zhou

A dynamic treatment regimen (DTR) is a pre-specified sequence of decision rules which maps baseline or time-varying measurements on an individual to a recommended intervention or set of interventions. Sequential multiple assignment…

Methodology · Statistics 2019-10-23 Brook Luers , Min Qian , Inbal Nahum-Shani , Connie Kasari , Daniel Almirall

Augmentation of disease diagnosis and decision-making in healthcare with machine learning algorithms is gaining much impetus in recent years. In particular, in the current epidemiological situation caused by COVID-19 pandemic, swift and…

Computers and Society · Computer Science 2021-02-23 Leopold Franz , Yash Raj Shrestha , Bibek Paudel

Generative Adversarial Networks (GANs) represent a promising class of generative networks that combine neural networks with game theory. From generating realistic images and videos to assisting musical creation, GANs are transforming many…

Machine Learning · Computer Science 2017-12-04 Alexandre Yahi , Rami Vanguri , Noémie Elhadad , Nicholas P. Tatonetti

Recent studies have shown that Dense Retrieval (DR) techniques can significantly improve the performance of first-stage retrieval in IR systems. Despite its empirical effectiveness, the application of DR is still limited. In contrast to…

Information Retrieval · Computer Science 2023-04-27 Haitao Li , Qingyao Ai , Jingtao Zhan , Jiaxin Mao , Yiqun Liu , Zheng Liu , Zhao Cao

Recommending medications for patients using electronic health records (EHRs) is a crucial data mining task for an intelligent healthcare system. It can assist doctors in making clinical decisions more efficiently. However, the inherent…

Artificial Intelligence · Computer Science 2022-04-22 Yang An , Liang Zhang , Mao You , Xueqing Tian , Bo Jin , Xiaopeng Wei

Health conditions among patients in intensive care units (ICUs) are monitored via electronic health records (EHRs), composed of numerical time series and lengthy clinical note sequences, both taken at irregular time intervals. Dealing with…

Machine Learning · Computer Science 2023-06-07 Xinlu Zhang , Shiyang Li , Zhiyu Chen , Xifeng Yan , Linda Petzold

Human digital twins (HDTs) are dynamic, data-driven virtual representations of individuals, continuously updated with multimodal data to simulate, monitor, and predict health trajectories. By integrating clinical, physiological, behavioral,…

Human-Computer Interaction · Computer Science 2025-08-19 Rong Pan , Hongyue Sun , Xiaoyu Chen , Giulia Pedrielli , Jiapeng Huang

Background: Clinical diagnosis is typically reached by following a series of steps recommended by guidelines authored by colleges of experts. Accordingly, guidelines play a crucial role in rationalizing clinical decisions but suffer from…

Machine Learning · Computer Science 2024-04-10 Lillian Muyama , Antoine Neuraz , Adrien Coulet
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