Related papers: A New Proton CT Scanner

Accurate dose calculation is vitally important for proton therapy. Pencil beam (PB) model-based dose calculation is fast but inaccurate due to the approximation when dealing with inhomogeneities. Monte Carlo (MC) dose calculation is the…

A feasibility study of the megavoltage (MV) computed tomography (CT) for imaging large cargos has been performed. The MV cargo CT system has imaging field of view of 3.25m in diameter. The system design includes a compact x-ray source and…

Purpose: Radiotherapy commonly relies on CT, but there is growing interest in using hybrid PET/MR. Therefore, dedicated hardware setups have been proposed for PET/MR systems which enable imaging in radiotherapy treatment position. These…

Photon counting detection is a promising approach toward effectively reducing the radiation dose in x-ray computed tomography (CT). Full CT reconstruction from a fraction of the detected photons required by scintillation-based detectors has…

We have used an inexpensive 3D printer mounting an inexpensive pre-irradiated silicon diode to measure the 2D dose distribution of a small (approximately 10mm FWHM) proton beam. z was measured with high resolution whereas x was changed on a…

Radiation therapy plays a crucial role in cancer treatment, necessitating precise delivery of radiation to tumors while sparing healthy tissues over multiple days. Computed tomography (CT) is integral for treatment planning, offering…

Background: Upright proton therapy with compact delivery systems has the potential to reduce costs for treatments but could also lead to broadening of the beam penumbra due to energy selection close to the patient. Purpose: This study aims…

PET imaging is widely employed for observing biological metabolic activities within the human body. However, numerous benign conditions can cause increased uptake of radiopharmaceuticals, confounding differentiation from malignant tumors.…

Positron Emission Tomography (PET) and Computed Tomography (CT) are essential for diagnosing, staging, and monitoring various diseases, particularly cancer. Despite their importance, the use of PET/CT systems is limited by the necessity for…

Proton therapy offers superior organ-at-risk sparing but is highly sensitive to anatomical changes, making accurate deformable image registration (DIR) across longitudinal CT scans essential. Conventional DIR methods are often too slow for…

In this work we present a novel system for PET estimation using CT scans. We explore the use of fully convolutional networks (FCN) and conditional generative adversarial networks (GAN) to export PET data from CT data. Our dataset includes…

This work is concerned with applying iterative image reconstruction, based on constrained total-variation minimization, to low-intensity X-ray CT systems that have a high sampling rate. Such systems pose a challenge for iterative image…

We propose an oAPT workflow that incorporates all these functionalities and validate its clinical implementation feasibility with prostate patients. AI-based auto-segmentation tool AccuContourTM (Manteia, Xiamen, China) was seamlessly…

Stereotactic body radiation therapy (SBRT) refers to focusing high-energy rays in three-dimensional space on the tumor lesion area, reducing the dose received by surrounding normal tissues, which can effectively improve the local control…

Due to its wide field of view, cone-beam computed tomography (CBCT) is plagued by large amounts of scatter, where attenuated photons hit the detector, and corrupt the linear models used for reconstruction. Given that one can generate a good…

Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…

We previously demonstrated near-field speckle scanning based x-ray imaging to be an easy-to-implement phase sensing method capable of providing both high sensitivity and high resolution. Yet, this performance combination could only be…

Compared with conventional single-energy computed tomography (CT), dual-energy CT (DECT) provides better material differentiation but most DECT imaging systems require dual full-angle projection data at different X-ray spectra. Relaxing the…

Range uncertainties in proton therapy hamper treatment precision. Prompt gamma-rays were suggested 16 years ago for real-time range verification, and have already shown promising results in clinical studies with collimated cameras.…

Purpose: The purpose of this work was to provide a flexible platform for FLASH research with protons by adapting a former clinical pencil beam scanning gantry to irradiations with ultrahigh dose rates. Methods: PSI Gantry 1 treated patients…