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We propose a new theoretical method for the calculation of the interaction energy between macromolecular systems at large distances. The method provides a linear scaling of the computing time with the system size and is considered as an…

Biological Physics · Physics 2009-11-13 Ilia A. Solov'yov , Alexander V. Yakubovich , Andrey V. Solov'yov , Walter Greiner

The Fast Multipole Method (FMM) reduces the computation of pairwise two-body interactions among $N$-particles to order $N$, whose computation cost should be of order $N^2$ by brute force. However, its implementation is somewhat complicated…

Computational Physics · Physics 2020-09-03 Yasuhiro Kajima

The molecular dipole moment ($\boldsymbol{\mu}$) is a central quantity in chemistry. It is essential in predicting infrared and sum-frequency generation spectra, as well as induction and long-range electrostatic interactions. Furthermore,…

Chemical Physics · Physics 2020-10-14 Max Veit , David M. Wilkins , Yang Yang , Robert A. DiStasio , Michele Ceriotti

Simulating charged many-body systems has been a computational demanding task due to the long-range nature of electrostatic interaction. For the multi-scale model of electrolytes which combines the strengths of atomistic/continuum…

Computational Physics · Physics 2022-07-22 Jing Fu , Zecheng Gan

The fast multipole method (FMM) has had great success in reducing the computational complexity of solving the boundary integral form of the Helmholtz equation. We present a formulation of the Helmholtz FMM that uses Fourier basis functions…

Numerical Analysis · Mathematics 2014-03-20 Cris Cecka , Eric Darve

Kinetic Monte Carlo (KMC) is an important computational tool in physics and chemistry. In contrast to standard Monte Carlo, KMC permits the description of time dependent dynamical processes and is not restricted to systems in equilibrium.…

Computational Physics · Physics 2020-04-22 William Robert Saunders , James Grant , Eike Hermann Müller , Ian Thompson

The structural dynamics of biological macromolecules, such as proteins, DNA/RNA, or their complexes, are strongly influenced by protonation changes of their typically many titratable groups, which explains their pH sensitivity. In turn,…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-06 Bartosz Kohnke , Eliane Briand , Carsten Kutzner , Helmut Grubmüller

The off-resonant hyperpolarizability is calculated using the dipole-free sum-over-stats expression from a randomly chosen set of energies and transition dipole moments that are forced to be consistent with the sum rules. The process is…

Optics · Physics 2009-11-13 Mark C. Kuzyk , Mark G. Kuzyk

While fast multipole methods (FMMs) are in widespread use for the rapid evaluation of potential fields governed by the Laplace, Helmholtz, Maxwell or Stokes equations, their coupling to high-order quadratures for evaluating layer potentials…

Numerical Analysis · Mathematics 2021-04-26 Leslie Greengard , Michael O'Neil , Manas Rachh , Felipe Vico

Molecular dynamics simulations of biomolecules have been widely adopted in biomedical studies. As classical point-charge models continue to be used in routine biomolecular applications, there have been growing demands on developing…

Computational Physics · Physics 2020-10-28 Haixin Wei , Ruxi Qi , Junmei Wang , Piotr Cieplak , Yong Duan , Ray Luo

We develop a computational method for modeling electrostatic interactions of arbitrarily-shaped, polarizable objects on colloidal length scales, including colloids/nanoparticles, polymers, and surfactants, dispersed in explicit ion…

Soft Condensed Matter · Physics 2024-06-18 Emily Krucker-Velasquez , James W. Swan , Zachary Sherman

I describe a modification to the original Fast Multipole Method (FMM) of Greengard & Rokhlin that approximates the gravitation field of an FMM cell as a small uniform grid (a "gridlet") of effective masses. The effective masses on a gridlet…

Computational Physics · Physics 2019-07-31 Nickolay Y. Gnedin

Long-range electrostatics and polarization remain central obstacles to extending machine learning interatomic potentials (MLIPs) to ionic, polar, and interfacial systems. Here, we introduce a semi-local framework for learning electrostatics…

Materials Science · Physics 2026-05-08 Dongjin Kim , Daniel S. King , Yoonjae Park , Roya Savoj , Sebastien Hamel , Xiaoyu Wang , Bingqing Cheng

Accurate representation of the molecular electrostatic potential, which is often expanded in distributed multipole moments, is crucial for an efficient evaluation of intermolecular interactions. Here we introduce a machine learning model…

Chemical Physics · Physics 2017-10-09 Tristan Bereau , Denis Andrienko , O. Anatole von Lilienfeld

We apply relativistic many-body methods to compute static differential polarizabilities for transitions inside the ground-state hyperfine manifolds of monovalent atoms and ions. Knowing this transition polarizability is required in a number…

Atomic Physics · Physics 2011-07-13 V. A. Dzuba , V. V. Flambaum , K. Beloy , A. Derevianko

The quality of biomolecular simulations critically depends on the accuracy of the force field used to calculate the potential energy of the molecular configurations. Currently, most simulations employ non-polarisable force fields, which…

Biological Physics · Physics 2020-02-11 V. S. Sandeep Inakollu , Daan P. Geerke , Christopher N. Rowley , Haibo Yu

We study a simple model consisting of an atomic ion and a polar molecule trapped in a single setup, taking into consideration their electrostatic interaction. We determine analytically their collective modes of excitation as a function of…

Atomic Physics · Physics 2016-08-11 Jordi Mur-Petit , Juan José García-Ripoll

Fast Multipole Methods (FMMs) based on the oscillatory Helmholtz kernel can reduce the cost of solving N-body problems arising from Boundary Integral Equations (BIEs) in acoustic or electromagnetics. However, their cost strongly increases…

Numerical Analysis · Mathematics 2022-02-11 Igor Chollet , Xavier Claeys , Pierre Fortin , Laura Grigori

Describing long-ranged electrostatics using short-ranged pair potentials is appealing since the computational complexity scales linearly with the number of particles. The foundation of this approach is to mimic the long-ranged medium…

Statistical Mechanics · Physics 2020-05-13 Björn Stenqvist , Vidar Aspelin , Mikael Lund

We present an efficient integral equation approach to solve the heat equation, $u_t (\x) - \Delta u(\x) = F(\x,t)$, in a two-dimensional, multiply connected domain, and with Dirichlet boundary conditions. Instead of using integral equations…

Numerical Analysis · Mathematics 2010-08-02 Mary-Catherine Kropinski , Bryan Quaife