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Partially inspired by features of computation in visual cortex, deep neural networks compute hierarchical representations of their inputs. While these networks have been highly successful in machine learning, it remains unclear to what…
The active inference framework (AIF) is a promising new computational framework grounded in contemporary neuroscience that can produce human-like behavior through reward-based learning. In this study, we test the ability for the AIF to…
Predicting disease progression from longitudinal imaging is useful for clinical decision making and trial design. Recent methods have moved toward increasing generative complexity, but the conditions under which this complexity is necessary…
Quantum optical neurons (QONs) are emerging as promising computational units that leverage photonic interference to perform neural operations in an energy-efficient and physically grounded manner. Building on recent theoretical proposals,…
Artificial intelligence, trained via machine learning or computational statistics algorithms, holds much promise for the improvement of small molecule drug discovery. However, structure-activity data are high dimensional with low…
To detect and segment objects in images based on their content is one of the most active topics in the field of computer vision. Nowadays, this problem can be addressed using Deep Learning architectures such as Faster R-CNN or YOLO, among…
Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) play essential roles in animal reproduction. They exert their function through binding to their cognate receptors, which belong to the large family of G protein-coupled…
A general-purpose computational homogenization framework is proposed for the nonlinear dynamic analysis of membranes exhibiting complex microscale and/or mesoscale heterogeneity characterized by in-plane periodicity that cannot be…
The meteoric rise in the adoption of deep neural networks as computational models of vision has inspired efforts to "align" these models with humans. One dimension of interest for alignment includes behavioral choices, but moving beyond…
While generative models have recently become ubiquitous in many scientific areas, less attention has been paid to their evaluation. For molecular generative models, the state-of-the-art examines their output in isolation or in relation to…
Large vision foundation models have been widely adopted for retinal disease classification without systematic evidence justifying their parameter requirements. In the present work we address two critical questions: First, are large…
The traditional methods of the biology, based on illustrative descriptions and linear logic explanations, are discussed. This work aims to improve this approach by introducing alternative tools to describe and represent complex biological…
Deep learning models generating structural brain MRIs have the potential to significantly accelerate discovery of neuroscience studies. However, their use has been limited in part by the way their quality is evaluated. Most evaluations of…
Although we have seen a proliferation of algorithms for recommending visualizations, these algorithms are rarely compared with one another, making it difficult to ascertain which algorithm is best for a given visual analysis scenario.…
Human action recognition from skeletal data is a hot research topic and important in many open domain applications of computer vision, thanks to recently introduced 3D sensors. In the literature, naive methods simply transfer off-the-shelf…
Neuroscience and artificial intelligence (AI) both face the challenge of interpreting high-dimensional neural data, where the comparative analysis of such data is crucial for revealing shared mechanisms and differences between these complex…
Computational modeling helps neuroscientists to integrate and explain experimental data obtained through neurophysiological and anatomical studies, thus providing a mechanism by which we can better understand and predict the principles of…
The design of activation functions is a growing research area in the field of neural networks. In particular, instead of using fixed point-wise functions (e.g., the rectified linear unit), several authors have proposed ways of learning…
Accurate predictions of reactive mixing are critical for many Earth and environmental science problems. To investigate mixing dynamics over time under different scenarios, a high-fidelity, finite-element-based numerical model is built to…
The concept of a cell$'$s receptive field is a bedrock in systems neuroscience, and the classical static description of the receptive field has had enormous success in explaining the fundamental mechanisms underlying visual processing.…