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Major depressive disorder persistently stands as a major public health problem. While some progress has been made toward effective treatments, the neural mechanisms that give rise to the disorder remain poorly understood. In this…

Aging is thought to be a consequence of intrinsic breakdowns in how genetic information is processed. But mounting experimental evidence suggests that aging can be slowed. To help resolve this mystery, I derive a mortality equation which…

More than one million people commit suicide every year worldwide. The costs of daily cares, social stigma and treatment issues are still hard barriers to overcome in mental health. Most symptoms of mental disorders are related to the…

A recent contribution to research on age and well-being (Blanchflower 2021) found that the impact of age on happiness is "u-shaped" virtually everywhere: happiness declines towards middle age and subsequently rises, in almost all countries.…

Background: Suicide issue is of great concern in China. Social media provides an active approach to understanding suicide individuals in terms of their behavior and language use. Aims: This study investigates how suicide Microblog users in…

We propose a probabilistic mortality forecasting model that can be applied to derive forecasts for populations with regular and irregular mortality developments. Our model (1) uses rates of mortality improvement to model dynamic age…

In the light of increasing clues on social media impact on self-harm and suicide risks, there is still no evidence on who are and how factually engaged in suicide-related online behaviors. This study reports new findings of high-performance…

Alignment between subjective sense of time and chronological time can become skewed as a result of pharmacological interventions, neurodegenerative diseases (such as Parkinson's disease), or even in the moments preceding brain death.…

Recently we developed a new framework in Hirz et al (2015) to model stochastic mortality using extended CreditRisk$^+$ methodology which is very different from traditional time series methods used for mortality modelling previously. In this…

Suicide is the tenth leading cause of death in the United States, yet evidence on medication-related risk or protection remains limited. Most post-marketing studies examine one drug class at a time or rely on empirical-Bayes shrinkage with…

Disparity in suicide rates between urban and suburban/rural areas is growing, with rural areas typically witnessing higher suicide rates in the U.S. However, previous studies often ignored the effect of socio-environmental factors on the…

Smoking of tobacco is predicted to cause approximately six million deaths worldwide in 2014. Responding effectively to this epidemic requires a thorough understanding of how smoking behaviour is transmitted and modified. Here, we present a…

Urban scaling theory posits that urban indicators follow power-law relations with population, yet the evolution of these patterns - and the role of regional differences in settings marked by social inequalities and unplanned urbanization -…

Time perception is crucial for a coherent human experience. As life progresses, our perception of the passage of time becomes increasingly non-uniform, often feeling as though it accelerates with age. While various causes for this…

A new stochastic method for describing mortality is proposed and explored. It is based on differences of observed times series of the transform $\log(-\log x)$ of survival probabilities which seem to follow simple patterns over the years.…

Understanding and modeling mortality patterns, especially differences in mortality rates between populations, is vital for demographic analysis and public health planning. We compare three statistical models within the age-period framework…

Suicide is a critical issue in modern society. Early detection and prevention of suicide attempts should be addressed to save people's life. Current suicidal ideation detection methods include clinical methods based on the interaction…

The question of why we age is a fundamental one. It is about who we are, and it also might have critical practical aspects as we try to find ways to age slower. Or to not age at all. Different reasons point at distinct strategies for the…

The analysis of the demographic transition of the past century and a half, using both empirical data and mathematical models, has rendered a wealth of well-established facts, including the dramatic increases in life expectancy. Despite…

Suicide is an important but often misunderstood problem, one that researchers are now seeking to better understand through social media. Due in large part to the fuzzy nature of what constitutes suicidal risks, most supervised approaches…