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Droplet microfluidics offers a versatile platform for analyzing liquid samples. Despite its potential, there is a lack of techniques that allow to reliably probe individual circulating droplets. The prospect of combining droplet…

Quantitative Methods · Quantitative Biology 2024-03-08 Marc Sulliger , Jaime Ortega Arroyo , Romain Quidant

Microfluidics-based biochips are soon expected to revolutionize clinical diagnosis, DNA sequencing, and other laboratory procedures involving molecular biology. Most microfluidic biochips are based on the principle of continuous fluid flow…

Hardware Architecture · Computer Science 2011-11-09 Fei Su , Krishnendu Chakrabarty

To facilitate the use and portability of Lab on a chip technology, it is desirable to avoid the use of bulky electronic systems for flow control. Developed self-powered microsystems typically move only small volumes of fluid performing up…

Microfluidic mixing is a fundamental functionality in most lab on a chip (LOC) systems,whereas realization of efficient mixing is challenging in microfluidic channels due to the small Reynolds numbers. Here, we design and fabricate a…

Applied Physics · Physics 2020-01-10 Wenbo Li , Wei Chu , Peng Wang , Jia Qi , Zhe Wang , Jintian Lin , Min Wang , Ya Cheng

Advances in chip-scale photonic-electronic integration are enabling a new generation of foundry-manufacturable implantable silicon neural probes incorporating nanophotonic waveguides and microelectrodes for optogenetic stimulation and…

Droplet-based high throughput biomolecular screening and combinatorial synthesis entail a viable indexing strategy to be developed for the identification of each micro-reactor. Here, we propose a novel indexing scheme based on the…

Soft Condensed Matter · Physics 2018-11-29 Wenya Song , Gungun Lin , Jin Ge , Jurgen Fassbender , Denys Makarov

Integrated micro-nanochannel networks in fluidic devices are desirable in a number of applications ranging from self-healing/cooling materials to bioengineering. The conventional micro-manufacturing techniques are capable of either…

Materials Science · Physics 2017-04-10 Prasoon Kumar , Prasanna S Gandhi , Mainak Majumder

Given the ever-increasing advances of digital microfluidic biochips and their application in a wide range of areas including bio-chemistry experiments, diagnostics, and monitoring purposes like air and water quality control and etc.,…

Emerging Technologies · Computer Science 2020-01-01 Alireza Abdoli

Solid-state micro/nanopores play an important role in the sensing field because of their high stability and controllable size. Aiming at problems of complex processes and high costs in pore manufacturing, we propose a convenient and…

Chemical Physics · Physics 2024-04-04 Rui Liu , Zhe Liu , Jianfeng Li , Yinghua Qiu

In this work, we introduce the novel technique of in-chip drop on demand, which consists in dispensing picoliter to nanoliter drops on demand directly in the liquid-filled channels of a polymer microfluidic chip, at frequencies up to 2.5…

Quantitative Methods · Quantitative Biology 2009-12-16 Jie Xu , Daniel Attinger

The paper describes a novel concept for a low cost microfluidic platform utilizing materials and processes used in low cost thermal inkjet printing. The concept re-purposes the jetting elements to create pumps, mixers, and valves all…

Fluid Dynamics · Physics 2016-10-28 Alexander N. Govyadinov , Erik Torniainen , Pavel Kornilovitch , David Markel

Microfluidics involves the manipulation of flows at the microscale, typically requiring external power sources to generate pressure gradients. Alternatively, harnessing flows from active fluids, which are usually chaotic, has been proposed…

Microfluidics has revolutionized control over small volumes through the use of physical barriers. However, the rigidity of these barriers limits flexibility in applications. We present an optofluidic toolbox that leverages structured light…

Acoustic manipulation in microfluidic devices enables contactless handling of biological cells for Lab-on-Chip applications. This paper analyzes the controllability of multi-particle systems in a one-dimensional acoustic standing wave…

Systems and Control · Electrical Eng. & Systems 2025-04-07 Dongjun Wu , Guilherme Perticarari , Thierry Baasch

Today, the area of point-of-care diagnostics is synonymous with paper microfluidics where cheap, disposable, and on-the-spot detection toolkits are being developed for a variety of chemical tests. In this work, we present a novel…

Image and Video Processing · Electrical Eng. & Systems 2022-06-24 Zach Njus , Taejoon Kong , Upender Kalwa , Christopher Legner , Matthew Weinstein , Shawn Flanigan , Jenifer Saldanha , Santosh Pandey

The efficient mixing of fluid samples in miniaturized total analysis systems is essential for numerous applications including biological screening assays, chemical extraction, polymerization, cell analysis, and protein folding. Miniaturized…

Fluid Dynamics · Physics 2022-10-25 S. A. Iqrar , J. Park , M. Afzal , H. J. Sung

As the demand for more efficient and adaptive computing grows, nature-inspired architectures offer promising alternatives to conventional electronic designs. Microfluidic platforms, drawing on biological forms and fluid dynamics, present a…

Neural and Evolutionary Computing · Computer Science 2025-08-18 Jacob Clouse , Thomas Ramsey , Samitha Somathilaka , Nicholas Kleinsasser , Sangjin Ryu , Sasitharan Balasubramaniam

Molecular Communications (MC), transferring information via chemical signals, holds promise for transformative healthcare applications within the Internet of Bio-Nano Things (IoBNT) framework. Despite promising advances toward practical MC…

Emerging Technologies · Computer Science 2025-02-03 Maide Miray Albay , Eren Akyol , Fariborz Mirlou , Levent Beker , Murat Kuscu

Digital microfluidic biochips (DMFBs) are revolutionary biomedical devices towards diagnostics and point-of-care applications; the chips provide the capability of performing wide ranges of biochemistry and laboratory procedures, offering…

Emerging Technologies · Computer Science 2020-09-01 Alireza Abdoli , Sedigheh Farhadtoosky , Ali Jahanian

Microfluidics is an established multidisciplinary research domain with widespread applications in the fields of medicine, biotechnology and engineering. Conventional production methods of microfluidic chips have been limited to planar…