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High-intensity focused ultrasound (HIFU) is a promising treatment modality for the non-invasive ablation of pathogenic tissue in many organs. Optimal treatment planning strategies based on high-performance computing methods are expected to…

Medical Physics · Physics 2019-10-03 S. R. Haqshenas , P. Gélat , E. van 't Wout , T. Betcke , N. Saffari

Kidney cancer is a severe disease which can be treated non-invasively using high-intensity focused ultrasound (HIFU) therapy. However, tissue in front of the transducer and the deep location of kidney can cause significant losses to the…

Medical Physics · Physics 2018-11-12 Visa Suomi , Jiri Jaros , Bradley Treeby , Robin Cleveland

Objective: High-intensity focused ultrasound (HIFU) therapy can be used for non-invasive treatment of kidney (renal) cancer, but the clinical outcomes have been variable. In this study, the efficacy of renal HIFU therapy was studied using…

Medical Physics · Physics 2018-11-12 Visa Suomi , Jiri Jaros , Bradley Treeby , Robin Cleveland

Quantitative ultrasound (QUS) analyzes the ultrasound backscattered data to find the properties of scatterers that correlate with the tissue microstructure. Statistics of the envelope of the backscattered radiofrequency (RF) data can be…

Signal Processing · Electrical Eng. & Systems 2024-01-23 Ali K. Z. Tehrani , Guy Cloutier , An Tang , Ivan M. Rosado-Mendez , Hassan Rivaz

Current interstitial techniques of tumor ablation face challenges that ultrasound technologies could meet. The ablation radius and directionality of the ultrasound beam could improve the efficiency and precision. Here, a 9gauge…

Classical Physics · Physics 2025-11-07 Thomas Biscaldi , Romain l'Huillier , Laurent Milot , W Apoutou N'Djin

High intensity focused ultrasound (HIFU) has many applications ranging from thermal ablation of cancer to hemostasis. Although focused ultrasound can seal a bleeding site, physical mechanisms of acoustic hemostasis are not fully understood…

Fluid Dynamics · Physics 2014-11-25 Maxim A. Solovchuk , Marc Thiriet , Tony W. H. Sheu

Heat enhancement at the target in a High Intensity Focused Ultrasound (HIFU) field is investigated by considering the effects of the injection of microbubbles in the vicinity of the tumor to be ablated. The interaction between the bubble…

Fluid Dynamics · Physics 2025-11-27 Aswin Gnanaskandan , Chao-Tsung Hsiao , Georges Chahine

The nonuniform fast Fourier transform (NUFFT) enables spectral methods for problems with irregularly spaced samples, with applications in medical imaging, molecular dynamics, and kinetic plasma simulations. Existing implementations are…

Computational Engineering, Finance, and Science · Computer Science 2026-05-12 Paul Fischill , Andreas Adelmann , Sriramkrishnan Muralikrishnan

High-Intensity Focused Ultrasound (HIFU) is a non-invasive therapy, yet its safety is often degraded by severe acoustic interference during continuous ultrasound guidance. Conventional HIFU interference suppression methods heavily rely on…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Dejia Cai , Ali Abdollahi , Xi Wang , Kun Yang , Zhaohui Guo , Xiaowei Zhou , Hao Chen

In various biomedical applications, precise focusing of nonlinear ultrasonic waves is crucial for efficiency and safety of the involved procedures. This work analyzes a class of shape optimization problems constrained by general…

Optimization and Control · Mathematics 2022-06-08 Mostafa Meliani , Vanja Nikolić

Transcranial ultrasound therapy uses focused acoustic energy to induce therapeutic bioeffects in the brain. Ultrasound must be transmitted through the skull, which is highly attenuating and heterogeneous, causing beam distortion, reducing…

Hyperspectral (HS) imaging presents itself as a non-contact, non-ionizing and non-invasive technique, proven to be suitable for medical diagnosis. However, the volume of information contained in these images makes difficult providing the…

MRI-guided High Intensity Focused Ultrasound (MRI-HIFU) is a promising method for the non-invasive ablation of pathological tissue in many organs, including mobile organs such as liver and kidney. The possibility to locally deposit thermal…

Medical Physics · Physics 2020-12-01 Baudouin Denis de Senneville , Chrit Moonen , Mario Ries

High Intensity Focused Ultrasound (HIFU) is a promising therapy for thermal ablation and hyperthermia, characterised by it noninvasiveness, high penetration depth. Effective HIFU thermo-therapy requires the ability to accurately predict…

Medical Physics · Physics 2020-07-14 Gajendra Singh , Anup Paul , Himanshu Shekhar , Abhijit Paul

The numerical simulation of weakly nonlinear ultrasound is important in treatment planning for focused ultrasound (FUS) therapies. However, the large domain sizes and generation of higher harmonics at the focus make these problems extremely…

Medical images such as 3D computerized tomography (CT) scans and pathology images, have hundreds of millions or billions of voxels/pixels. It is infeasible to train CNN models directly on such high resolution images, because neural…

Image and Video Processing · Electrical Eng. & Systems 2019-09-16 Le Hou , Youlong Cheng , Noam Shazeer , Niki Parmar , Yeqing Li , Panagiotis Korfiatis , Travis M. Drucker , Daniel J. Blezek , Xiaodan Song

Simulations of three dimensional ultrasound propagation in heterogeneous media are computationally intensive due to the constraints arising from the large size of the domain, which is on the order of hundreds of wavelengths, and the small…

Medical Physics · Physics 2020-03-17 Gianmarco Pinton

Developing efficient path integral (PI) methods for atomistic simulations of vibrational spectra in heterogeneous condensed phases and interfaces has long been a challenging task. Here, we present the h-CMD method, short for hybrid centroid…

Chemical Physics · Physics 2025-05-08 Dil K. Limbu , Nathan London , Md Omar Faruque , Mohammad R. Momeni

Both local details and global context are crucial in medical image segmentation, and effectively integrating them is essential for achieving high accuracy. However, existing mainstream methods based on CNN-Transformer hybrid architectures…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Dayu Tan , Zhenpeng Xu , Yansen Su , Xin Peng , Chunhou Zheng , Weimin Zhong

A radio interferometer indirectly measures the intensity distribution of the sky over the celestial sphere. Since measurements are made over an irregularly sampled Fourier plane, synthesising an intensity image from interferometric…

Instrumentation and Methods for Astrophysics · Physics 2014-03-18 Daniel Muscat
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