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Cone-beam breast computed tomography (CT) provides true 3D breast images with isotropic resolution and high-contrast information, detecting calcifications as small as a few hundred microns and revealing subtle tissue differences. However,…

Medical Physics · Physics 2019-12-18 Wenxiang Cong , Hongming Shan , Xiaohua Zhang , Shaohua Liu , Ruola Ning , Ge Wang

Purpose. - Radiotherapy is an important treatment for prostate cancer.During treatment sessions, bladder and rectal repletion is difficult to quantify and cannot be measured with a single and initial CT scan acquisition. Some methods, such…

Medical Physics · Physics 2011-04-06 Cyril Voyant , Katia Biffi , Leschi Delphine , Jerome Briancon , Celine Lantieri Marcovici

Two full rotating gantry with different nozzles (Multipurpose nozzle with MLC, Scanning Dedicated nozzle) with conventional cyclotron system is installed and under commissioning for various proton treatment options at Samsung Medical Center…

Background: Spectral shaping is a computed tomography (CT) dose optimization technique that adjusts source voltage and filtration to reduce patient radiation exposure without compromising image quality. Traditionally, radiation dose has…

Modern tomography involves gathering projection data from multiple directions and feeding them into a software algorithm for tomographic reconstruction. We focus our study on image reconstruction from Radon data in the setting of…

Numerical Analysis · Mathematics 2014-12-19 Maria Angela Narduzzo

We summarize recent results and ongoing activities in mathematical algorithms and computer science methods related to proton computed tomography (pCT) and intensity-modulated particle therapy (IMPT) treatment planning. Proton therapy…

Medical Physics · Physics 2021-08-24 Yair Censor , Keith E. Schubert , Reinhard W. Schulte

Particle physics simulations are the cornerstone of nuclear engineering applications. Among them radiotherapy (RT) is crucial for society, with 50% of cancer patients receiving radiation treatments. For the most precise targeting of tumors,…

Machine Learning · Computer Science 2021-09-10 Oscar Pastor-Serrano , Zoltán Perkó

The interplay between the beam delivery time structure and the patient motion makes 4D dose calculation (4DDC) important when treating moving tumors with intensity modulated proton therapy. 4DDC based on phase sorting of a 4DCT suffers from…

Medical Physics · Physics 2023-10-13 Ivar Bengtsson , Erik Engwall , Albin Fredriksson , Lars Glimelius

In dental cone-beam computed tomography (CBCT), compact and cost-effective system designs often use small detectors, resulting in a truncated field of view (FOV) that does not fully encompass the patient's head. In iterative reconstruction…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Hyoung Suk Park , Kiwan Jeon

A central problem in the field of radiation therapy (RT) is how to optimally deliver dose to a patient in a way that fully accounts for anatomical position changes over time. As current RT is a static process, where beam intensities are…

Medical Physics · Physics 2019-09-04 Rodney D. Wiersma , Xinmin Liu

Cone beam computed tomography (CBCT) is an important imaging technology widely used in medical scenarios, such as diagnosis and preoperative planning. Using fewer projection views to reconstruct CT, also known as sparse-view reconstruction,…

Image and Video Processing · Electrical Eng. & Systems 2024-06-07 Yiqun Lin , Jiewen Yang , Hualiang Wang , Xinpeng Ding , Wei Zhao , Xiaomeng Li

Modeling the absorbed dose during X-ray imaging is essential for optimizing radiation exposure. Monte Carlo simulations (MCS) are the gold standard for precise 3D dose estimation but require significant computation time. Deep learning…

Medical Physics · Physics 2025-02-14 Maxime Rousselot , Jing Zhang , Didier Benoit , Chi-Hieu Pham , Julien Bert

The International Electrotechnical Commission (IEC) has previously defined standard rotation operators for positive gantry, collimator and couch rotations for the radiotherapy DICOM coordinate system that is commonly used by treatment…

Medical Physics · Physics 2014-06-03 Richard M. Schmitz , Oliver Telfer , Reid W. Townson , Sergei Zavgorodni

Objective: Machine learning (ML) based radiation treatment (RT) planning addresses the iterative and time-consuming nature of conventional inverse planning. Given the rising importance of Magnetic resonance (MR) only treatment planning…

Medical Physics · Physics 2022-06-13 Aly Khalifa , Jeff Winter , Inmaculada Navarro , Chris McIntosh , Thomas G. Purdie

Cone-beam CT (CBCT) is widely used in clinical radiotherapy for image-guided treatment, improving setup accuracy, adaptive planning, and motion management. However, slow gantry rotation limits performance by introducing motion artifacts,…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Yuan Gao , Shaoyan Pan , Mingzhe Hu , Huiqiao Xie , Jill Remick , Chih-Wei Chang , Justin Roper , Zhen Tian , Xiaofeng Yang

Cone-beam computed tomography (CBCT) is routinely collected during image-guided radiation therapy (IGRT) to provide updated patient anatomy information for cancer treatments. However, CBCT images often suffer from streaking artifacts and…

Computer Vision and Pattern Recognition · Computer Science 2023-11-02 Jiarui Zhu , Werxing Chen , Hongfei Sun , Shaohua Zhi , Jing Qin , Jing Cai , Ge Ren

This research considers potential dose increase in target due to cisplatin (Pt) concentration and radiation type. Cisplatin concentrations from 0.003 to 120 mM were used. Monte-Carlo simulation of Linear accelerator (Elekta Synergy) and…

Medical Physics · Physics 2020-08-26 A. A. Baulin

Online dose calculations before radiation treatment have applications in dose delivery verification, plan adaptation, and treatment planning. We propose a novel CBCT imaging pipeline to enhance accuracy. Our approach aims to improve HU…

While compressed sensing (CS) based reconstructions have been developed for low-dose CBCT, a clear understanding on the relationship between the image quality and imaging dose at low dose levels is needed. In this paper, we qualitatively…

Medical Physics · Physics 2015-06-03 Hao Yan , Laura Cervino , Xun Jia , Steve B. Jiang

Four-dimensional Cone Beam Computed Tomography (4D-CBCT) has been developed to provide respiratory phase resolved volumetric imaging in image guided radiation therapy (IGRT). Inadequate number of projections in each phase bin results in low…

Medical Physics · Physics 2015-06-03 Xun Jia , Zhen Tian , Yifei Lou , Jan-Jakob Sonke , Steve B. Jiang
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