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The adaptation of large asexual populations is hampered by the competition between independently arising beneficial mutations in different individuals, which is known as clonal interference. Fisher and Muller proposed that recombination…

Populations and Evolution · Quantitative Biology 2013-08-16 Su-Chan Park , Joachim Krug

In this paper, we consider a new kind of evolution multivalued quasi-variational inequalities with feedback effect and a nonlinear bifunction which contain several (evolution) quasi-variational/hemivariational inequalities as special cases.…

Functional Analysis · Mathematics 2024-05-29 Shengda Zeng , Vicenţiu D. Rădulescu

We analyze a replicator-mutator model arising in the context of directed evolution [23], where the selection term is modulated over time by the mean-fitness. We combine a Cumulant Generating Function approach [13] and a spatio-temporal…

Analysis of PDEs · Mathematics 2019-01-24 Matthieu Alfaro , Mario Veruete

Arguing about the equilibrium distribution of continuous-time Markov chains can be vital for showing properties about the underlying systems. For example in biological systems, bistability of a chemical reaction network can hint at its…

Probability · Mathematics 2010-07-20 Tugrul Dayar , Holger Hermanns , David Spieler , Verena Wolf

We study the probabilistic evolution of a birth and death continuous time measure-valued process with mutations and ecological interactions. The individuals are characterized by (phenotypic) traits that take values in a compact metric…

Probability · Mathematics 2009-04-23 Pierre Collet , Servet Martinez , Sylvie Méléard , Jaime San Martin

Using the Hamilton-Jacobi equation approach to study genomes of length $L$, we obtain 1/L corrections for the steady state population distributions and mean fitness functions for horizontal gene transfer model, as well as for the diploid…

Populations and Evolution · Quantitative Biology 2015-06-12 Zara Kirakosyan , David B. Saakian , Chin Kun Hu

We suggest a natural approach that leads to a modification of classical quasispecies models and incorporates the possibility of population extinction in addition to growth. The resulting modified models are called open. Their essential…

Populations and Evolution · Quantitative Biology 2019-03-25 Ivan Yegorov , Artem S. Novozhilov , Alexander S. Bratus

The Bak--Sneppen model is an abstract representation of a biological system that evolves according to the Darwinian principles of random mutation and selection. The species in the system are characterized by a numerical fitness value…

Probability · Mathematics 2015-06-23 Eckhard Schlemm

We consider the following frustrated optimization problem: given a prior probability distribution $q$, find the distribution $p$ minimizing the relative entropy with respect to $q$ such that $\textrm{mean}(p)$ is fixed and large. We show…

Statistical Mechanics · Physics 2016-12-06 Matteo Smerlak

This paper develops mathematical models describing the evolutionary dynamics of both asexually and sexually reproducing populations of diploid unicellular organisms. We consider two forms of genome organization. In one case, we assume that…

Populations and Evolution · Quantitative Biology 2009-07-17 Maya Kleiman , Emmanuel Tannenbaum

Standard neutral population genetics theory with a strictly fixed population size has important limitations. An alternative model that allows independently fluctuating population sizes and reproduces the standard neutral evolution is…

Populations and Evolution · Quantitative Biology 2017-03-08 Thiparat Chotibut , David R. Nelson

We study a variant of the Cucker-Smale system with distributed reaction delays. Using backward-forward and stability estimates on the quadratic velocity fluctuations we derive sufficient conditions for asymptotic flocking of the solutions.…

Dynamical Systems · Mathematics 2020-05-12 Jan Haskovec , Ioannis Markou

The long-term growth rate of populations in varying environments quantifies the evolutionary value of processing the information that biological individuals inherit from their ancestors and acquire from their environment. Previous models…

Populations and Evolution · Quantitative Biology 2021-06-30 Anton S Zadorin , Olivier Rivoire

An equation for the evolution of the distribution of wealth in a population of economic agents making binary transactions with a constant total amount of "money" has recently been proposed by one of us (RLR). This equation takes the form of…

Adaptation and Self-Organizing Systems · Physics 2014-07-29 Yves Pomeau , Ricardo Lopez-Ruiz

We discuss the possibility of deriving an H-theorem for the nonlinear discrete time evolution known as Ulam's redistribution of energy problem. In this model particles are paired at random and then their total energy is redistributed…

Statistical Mechanics · Physics 2013-06-06 S. M. Apenko

Kingman's model describes the evolution of a one-locus haploid population of infinite size and discrete generations under the competition of selection and mutation. A random generalisation has been made in a previous paper which assumes all…

Probability · Mathematics 2020-12-01 Linglong Yuan

A new approach to understanding evolution [Val09], namely viewing it through the lens of computation, has already started yielding new insights, e.g., natural selection under sexual reproduction can be interpreted as the Multiplicative…

Populations and Evolution · Quantitative Biology 2016-04-26 Ruta Mehta , Ioannis Panageas , Georgios Piliouras , Prasad Tetali , Vijay V. Vazirani

A punctuated equilibrium model of biological evolution with relative fitness between different species being the fundamental driving force of evolution is introduced. Mutation is modeled as a fitness updating cellular automaton process…

Condensed Matter · Physics 2015-06-25 H. F. Chau , L. Mak , P. K. Kwok

We revisit the classical population genetics model of a population evolving under multiplicative selection, mutation and drift. The number of beneficial alleles in a multi-locus system can be considered a trait under exponential selection.…

adap-org · Physics 2007-05-23 Magnus Rattray , Jonathan L. Shapiro

We consider a fitness-structured population model with competition and migration between nearest neighbors. Under a combination of large population and rare migration limits we are particularly interested in the asymptotic behavior of the…

Probability · Mathematics 2012-07-20 Anton Bovier , Shi-Dong Wang