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Frequent tree mining asks us to enumerate tree patterns that occur frequently in a database of rooted trees. This problem is motivated by tree-structured data in bioinformatics, such as glycans and pseudoknot-free RNA secondary structures.…

Data Structures and Algorithms · Computer Science 2026-05-21 Kenta Komoto , Kazuhiro Kurita , Hirotaka Ono

In recent decades, phylogenetic networks have become a standard tool in modeling evolutionary processes. Nevertheless, basic combinatorial questions about them are still largely open. For instance, even the asymptotic counting problem for…

Combinatorics · Mathematics 2018-11-13 Michael Fuchs , Bernhard Gittenberger , Marefatollah Mansouri

Arboreal networks are multi-rooted phylogenetic networks whose underlying graph is a tree. We give an encoding of stack-free arboreal networks in terms of triplets and the novel concept of a duet. This yields a polynomial time algorithm to…

Discrete Mathematics · Computer Science 2026-05-05 Katharina T. Huber , Katherine St. John

A normal (phylogenetic) network with $k$ reticulations displays $2^k$ phylogenetic trees. In this paper, we establish an analogous result for tree-child (phylogenetic) networks with no underlying $3$-cycles. In particular, we show that a…

Combinatorics · Mathematics 2025-08-20 Charles Semple , Kristina Wicke

Orchard and tree-child networks share an important property with phylogenetic trees: they can be completely reduced to a single node by iteratively deleting cherries and reticulated cherries. As it is the case with phylogenetic trees, the…

Populations and Evolution · Quantitative Biology 2024-03-22 Tomás M. Coronado , Joan Carles Pons , Gabriel Riera

The minimal number of rooted subtree prune and regraft (rSPR) operations needed to transform one phylogenetic tree into another one induces a metric on phylogenetic trees - the rSPR-distance. The rSPR-distance between two phylogenetic trees…

Combinatorics · Mathematics 2023-06-22 Jonathan Klawitter

Phylogenetic networks are used to display the relationship of different species whose evolution is not treelike, which is the case, for instance, in the presence of hybridization events or horizontal gene transfers. Tree inference methods…

Populations and Evolution · Quantitative Biology 2014-05-02 Mareike Fischer , Leo van Iersel , Steven Kelk , Celine Scornavacca

The Tree of Life is the graphical structure that represents the evolutionary process from single-cell organisms at the origin of life to the vast biodiversity we see today. Reconstructing this tree from genomic sequences is challenging due…

Populations and Evolution · Quantitative Biology 2020-10-06 Claudia Solis-Lemus , Arrigo Coen , Cecile Ane

Tree containment problem is a fundamental problem in phylogenetic study, as it is used to verify a network model. It asks whether a given network contain a subtree that resembles a binary tree. The problem is NP-complete in general, even in…

Populations and Evolution · Quantitative Biology 2017-02-15 Andreas Gunawan

We introduce a notion of finite sampling consistency for phylogenetic trees and show that the set of finitely sampling consistent and exchangeable distributions on n leaf phylogenetic trees is a polytope. We use this polytope to show that…

Combinatorics · Mathematics 2019-03-06 Ben Hollering , Seth Sullivant

In this paper we investigate an extremal problem on binary phylogenetic trees. Given two such trees $T_1$ and $T_2$, both with leaf-set ${1,2,...,n}$, we are interested in the size of the largest subset $S \subseteq {1,2,...,n}$ of leaves…

Combinatorics · Mathematics 2013-02-21 Daniel M. Martin , Bhalchandra D. Thatte

A multi-labeled tree, or MUL-tree, is a phylogenetic tree where two or more leaves share a label, e.g., a species name. A MUL-tree can imply multiple conflicting phylogenetic relationships for the same set of taxa, but can also contain…

Data Structures and Algorithms · Computer Science 2012-06-29 Akshay Deepak , David Fernández-Baca , Michelle M. McMahon

In evolutionary biology, phylogenetic trees are commonly inferred from a set of characters (partitions) of a collection of biological entities (e.g., species or individuals in a population). Such characters naturally arise from molecular…

Populations and Evolution · Quantitative Biology 2023-11-17 Katharina T. Huber , Simone Linz , Vincent Moulton , Charles Semple

Euclidean Steiner trees are relevant to model minimal networks in real-world applications ubiquitously. In this paper, we study the feasibility of a hierarchical approach embedded with bundling operations to compute multiple and mutually…

Artificial Intelligence · Computer Science 2024-12-03 Victor Parque

Phylogenetic networks are graphs that are used to represent evolutionary relationships between different taxa. They generalize phylogenetic trees since for example, unlike trees, they permit lineages to combine. Recently, there has been…

Populations and Evolution · Quantitative Biology 2025-08-05 Katharina T. Huber , Leo van Iersel , Mark Jones , Vincent Moulton , Leonie Veenema - Nipius

The multispecies coalescent process models the genealogical relationships of genes sampled from several species, enabling useful predictions about phenomena such as the discordance between the gene tree and the species phylogeny due to…

Populations and Evolution · Quantitative Biology 2020-12-11 Jakub Truszkowski , Celine Scornavacca , Fabio Pardi

It is known that any two trees on the same $n$ leaves can be displayed by a network with $n-2$ reticulations, and there are two trees that cannot be displayed by a network with fewer reticulations. But how many reticulations are needed to…

Combinatorics · Mathematics 2026-03-11 Mathias Weller , Norbert Zeh

Phylogenetic networks are used to represent evolutionary scenarios in biology and linguistics. To find the most probable scenario, it may be necessary to compare candidate networks, to distinguish different networks, and to see when one…

Combinatorics · Mathematics 2020-04-10 Remie Janssen , Yukihiro Murakami

Invariants for complicated objects such as those arising in phylogenetics, whether they are invariants as matrices, polynomials, or other mathematical structures, are important tools for distinguishing and working with such objects. In this…

Populations and Evolution · Quantitative Biology 2022-04-06 Joan Carles Pons , Tomás M. Coronado , Michael Hendriksen , Andrew Francis

Tree-based networks are a class of phylogenetic networks that attempt to formally capture what is meant by "tree-like" evolution. A given non-tree-based phylogenetic network, however, might appear to be very close to being tree-based, or…

Populations and Evolution · Quantitative Biology 2020-01-17 Mareike Fischer , Andrew Francis